| GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures I Shimada, T Ueda, Y Kofuku, MT Eddy, K Wüthrich Nature Reviews Drug Discovery, 2018 | 222 | 2018 |
| Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor MT Eddy, MY Lee, ZG Gao, KL White, T Didenko, R Horst, M Audet, ... Cell, 2017 | 200 | 2017 |
| Intermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR MJ Bayro, GT Debelouchina, MT Eddy, NR Birkett, CE MacPhee, M Rosay, ... Journal of the American Chemical Society 133 (35), 13967-13974, 2011 | 185 | 2011 |
| Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling KL White, MT Eddy, ZG Gao, GW Han, T Lian, A Deary, N Patel, ... Structure, 2018 | 148 | 2018 |
| Structure and Mechanism of the Influenza A M218–60 Dimer of Dimers LB Andreas, M Reese, MT Eddy, V Gelev, QZ Ni, EA Miller, L Emsley, ... Journal of the American Chemical Society 137 (47), 14877-14886, 2015 | 121 | 2015 |
| A2A adenosine receptor functional states characterized by 19F-NMR L Sušac, MT Eddy, T Didenko, RC Stevens, K Wüthrich Proceedings of the National Academy of Sciences, 201813649, 2018 | 103 | 2018 |
| Spectroscopy by integration of frequency and time domain information for fast acquisition of high-resolution dark spectra Y Matsuki, MT Eddy, J Herzfeld Journal of the American Chemical Society 131 (13), 4648-4656, 2009 | 103 | 2009 |
| Magic angle spinning NMR investigation of influenza A M218− 60: support for an allosteric mechanism of inhibition LB Andreas, MT Eddy, RM Pielak, J Chou, RG Griffin Journal of the American Chemical Society 132 (32), 10958-10960, 2010 | 94 | 2010 |
| Lipid Dynamics and Protein–Lipid Interactions in 2D Crystals Formed with the β-Barrel Integral Membrane Protein VDAC1 MT Eddy, TC Ong, L Clark, O Teijido, PCA van der Wel, R Garces, ... Journal of the American Chemical Society 134 (14), 6375-6387, 2012 | 82 | 2012 |
| Proton Assisted Recoupling at High Spinning Frequencies JR Lewandowski, G De Paëpe, MT Eddy, J Struppe, W Maas, RG Griffin The Journal of Physical Chemistry B 113 (27), 9062-9069, 2009 | 70 | 2009 |
| Radio frequency-driven recoupling at high magic-angle spinning frequencies: homonuclear recoupling sans heteronuclear decoupling MJ Bayro, R Ramachandran, MA Caporini, MT Eddy, RG Griffin The Journal of chemical physics 128 (5), 052321, 2008 | 68 | 2008 |
| Adenosine A 2A receptor antagonists: From caffeine to selective non-xanthines KA Jacobson, ZG Gao, P Matricon, MT Eddy, J Carlsson British journal of pharmacology, 2020 | 66 | 2020 |
| Magic-angle-spinning NMR of the drug resistant S31N M2 proton transporter from influenza A LB Andreas, MT Eddy, JJ Chou, RG Griffin Journal of the American Chemical Society 134 (17), 7215-7218, 2012 | 65 | 2012 |
| 15N− 15N proton assisted recoupling in magic angle spinning NMR JR Lewandowski, GD Paëpe, MT Eddy, RG Griffin Journal of the American Chemical Society 131 (16), 5769-5776, 2009 | 60 | 2009 |
| Heteronuclear proton assisted recoupling GD Paëpe, JR Lewandowski, A Loquet, M Eddy, S Megy, A Böckmann, ... The Journal of chemical physics 134 (9), 03B601, 2011 | 57 | 2011 |
| β2-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop MT Eddy, T Didenko, RC Stevens, K Wüthrich Structure 24 (12), 2190-2197, 2016 | 54 | 2016 |
| Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor MT Eddy, ZG Gao, P Mannes, N Patel, KA Jacobson, V Katritch, ... Journal of the American Chemical Society, 2018 | 49 | 2018 |
| Structure of the alanine dipeptide in condensed phases determined by 13C NMR MA Mehta, EA Fry, MT Eddy, MT Dedeo, AE Anagnost, JR Long The Journal of Physical Chemistry B 108 (9), 2777-2780, 2004 | 48 | 2004 |
| Secondary Structure in the Core of Amyloid Fibrils Formed from Human β2m and its Truncated Variant ΔN6 Y Su, CJ Sarell, MT Eddy, GT Debelouchina, LB Andreas, CL Pashley, ... Journal of the American Chemical Society 136 (17), 6313-6325, 2014 | 46 | 2014 |
| Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR MT Eddy, Y Su, R Silvers, L Andreas, L Clark, G Wagner, G Pintacuda, ... Journal of biomolecular NMR 61 (3-4), 299-310, 2015 | 44 | 2015 |
Robert G. GriffinProfessor of Chemistry, MITVerified email at mit.edu
