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Bruce Sullenger
Bruce Sullenger
Duke University
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Year
Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras
JO McNamara, ER Andrechek, Y Wang, KD Viles, RE Rempel, E Gilboa, ...
Nature biotechnology 24 (8), 1005-1015, 2006
13162006
Aptamers: an emerging class of therapeutics
SM Nimjee, CP Rusconi, BA Sullenger
Annu. Rev. Med. 56, 555-583, 2005
11962005
Notch promotes radioresistance of glioma stem cells
J Wang, TP Wakeman, JD Lathia, AB Hjelmeland, XF Wang, RR White, ...
Stem cells 28 (1), 17-28, 2010
7662010
In vivo activity of nuclease-resistant siRNAs
JM Layzer, AP McCaffrey, AK Tanner, ZAN Huang, MA Kay, BA Sullenger
Rna 10 (5), 766-771, 2004
7662004
RNA aptamers as reversible antagonists of coagulation factor IXa
CP Rusconi, E Scardino, J Layzer, GA Pitoc, TL Ortel, D Monroe, ...
Nature 419 (6902), 90-94, 2002
6702002
Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication
BA Sullenger, HF Gallardo, GE Ungers, E Gilboa
Cell 63 (3), 601-608, 1990
6071990
Emerging clinical applications of RNA
BA Sullenger, E Gilboa
Nature 418 (6894), 252-258, 2002
5682002
Aptamers as therapeutics
SM Nimjee, RR White, RC Becker, BA Sullenger
Annual review of pharmacology and toxicology 57, 61-79, 2017
4842017
Antidote-mediated control of an anticoagulant aptamer in vivo
CP Rusconi, JD Roberts, GA Pitoc, SM Nimjee, RR White, G Quick Jr, ...
Nature biotechnology 22 (11), 1423-1428, 2004
4532004
Developing aptamers into therapeutics
RR White, BA Sullenger, CP Rusconi
The Journal of clinical investigation 106 (8), 929-934, 2000
3892000
Generation of species cross-reactive aptamers using “toggle” SELEX
R White, C Rusconi, E Scardino, A Wolberg, J Lawson, M Hoffman, ...
Molecular Therapy 4 (6), 567-573, 2001
3772001
Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice
JO McNamara, D Kolonias, F Pastor, RS Mittler, L Chen, PH Giangrande, ...
The Journal of clinical investigation 118 (1), 376-386, 2008
3572008
Ribozyme-mediated repair of defective mRNA by targeted trans-splicing
BA Sullenger, TR Cech
Nature 371 (6498), 619-622, 1994
3541994
In vivo selection of tumor-targeting RNA motifs
J Mi, Y Liu, ZN Rabbani, Z Yang, JH Urban, BA Sullenger, BM Clary
Nature chemical biology 6 (1), 22-24, 2010
3332010
Gene therapy progress and prospects: RNA aptamers
NS Que-Gewirth, BA Sullenger
Gene therapy 14 (4), 283-291, 2007
2792007
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA
BA Sullenger, TR Cech
Science 262 (5139), 1566-1569, 1993
2771993
Ribozyme-mediated repair of sickle β-globin mRNAs in erythrocyte precursors
N Lan, RP Howrey, SW Lee, CA Smith, BA Sullenger
Science 280 (5369), 1593-1596, 1998
2761998
Group II introns designed to insert into therapeutically relevant DNA target sites in human cells
H Guo, M Karberg, M Long, JP Jones III, B Sullenger, AM Lambowitz
science 289 (5478), 452-457, 2000
2642000
Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity
S Santulli-Marotto, SK Nair, C Rusconi, B Sullenger, E Gilboa
Cancer research 63 (21), 7483-7489, 2003
2612003
Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
NJ Ganson, TJ Povsic, BA Sullenger, JH Alexander, SL Zelenkofske, ...
Journal of Allergy and Clinical Immunology 137 (5), 1610-1613. e7, 2016
2602016
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