| Secretion of active membrane type 1 matrix metalloproteinase (MMP‐14) into extracellular space in microvesicular exosomes J Hakulinen, L Sankkila, N Sugiyama, K Lehti, J Keski‐Oja Journal of cellular biochemistry 105 (5), 1211-1218, 2008 | 322 | 2008 |
| Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis A Jiang, K Lehti, X Wang, SJ Weiss, J Keski-Oja, D Pei Proceedings of the National Academy of Sciences 98 (24), 13693-13698, 2001 | 306 | 2001 |
| Expression of collagenases-1 and-3 and their inhibitors TIMP-1 and-3 correlates with the level of invasion in malignant melanomas K Airola, T Karonen, M Vaalamo, K Lehti, J Lohi, AL Kariniemi, ... British journal of cancer 80 (5), 733-743, 1999 | 296 | 1999 |
| Fibroblasts in the tumor microenvironment: shield or spear? T Alkasalias, L Moyano-Galceran, M Arsenian-Henriksson, K Lehti International journal of molecular sciences 19 (5), 1532, 2018 | 266 | 2018 |
| Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface K Lehti, J Lohi, H Valtanen, J Keski-Oja Biochemical Journal 334 (2), 345-353, 1998 | 261 | 1998 |
| Regulation of membrane‐type matrix metalloproteinase‐1 expression by growth factors and phorbol 12‐myristate 13‐acetate J Lohi, K Lehti, J Westermarck, VM Kähäri, J Keski‐Oja European journal of biochemistry 239 (2), 239-247, 1996 | 225 | 1996 |
| Epilysin (MMP-28) induces TGF-β mediated epithelial to mesenchymal transition in lung carcinoma cells SA Illman, K Lehti, J Keski-Oja, J Lohi Journal of cell science 119 (18), 3856-3865, 2006 | 211 | 2006 |
| Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain K Lehti, H Valtanen, S Wickström, J Lohi, J Keski-Oja Journal of Biological Chemistry 275 (20), 15006-15013, 2000 | 204 | 2000 |
| Plasmin activates pro‐matrix metalloproteinase‐2 with a membrane‐type 1 matrix metalloproteinase‐dependent mechanism S Monea, K Lehti, J Keski‐Oja, P Mignatti Journal of cellular physiology 192 (2), 160-170, 2002 | 194 | 2002 |
| Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene J Lohi, K Lehti, H Valtanen, WC Parks, J Keski-Oja Gene 242 (1-2), 75-86, 2000 | 179 | 2000 |
| MMP2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells N Théret, K Lehti, O Musso, B Clément Hepatology 30 (2), 462-468, 1999 | 178 | 1999 |
| MT1-MMP releases latent TGF-β1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1 O Tatti, P Vehviläinen, K Lehti, J Keski-Oja Experimental cell research 314 (13), 2501-2514, 2008 | 177 | 2008 |
| Oligomerization through hemopexin and cytoplasmic domains regulates the activity and turnover of membrane-type 1 matrix metalloproteinase K Lehti, J Lohi, MM Juntunen, D Pei, J Keski-Oja Journal of Biological Chemistry 277 (10), 8440-8448, 2002 | 158 | 2002 |
| Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor W Zheng, T Tammela, M Yamamoto, A Anisimov, T Holopainen, ... Blood, The Journal of the American Society of Hematology 118 (4), 1154-1162, 2011 | 138 | 2011 |
| Membrane-type matrix metalloproteases as diverse effectors of cancer progression SP Turunen, O Tatti-Bugaeva, K Lehti Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (11), 1974-1988, 2017 | 135 | 2017 |
| An MT1-MMP-PDGF receptor-β axis regulates mural cell investment of the microvasculature K Lehti, E Allen, H Birkedal-Hansen, K Holmbeck, Y Miyake, TH Chun, ... Genes & development 19 (8), 979-991, 2005 | 131 | 2005 |
| KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition F Cheng, P Pekkonen, S Laurinavicius, N Sugiyama, S Henderson, ... Cell host & microbe 10 (6), 577-590, 2011 | 129 | 2011 |
| Quantitative proteomics analysis of vitreous humor from diabetic retinopathy patients S Loukovaara, H Nurkkala, F Tamene, E Gucciardo, X Liu, P Repo, ... Journal of proteome research 14 (12), 5131-5143, 2015 | 120 | 2015 |
| EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion N Sugiyama, E Gucciardo, O Tatti, M Varjosalo, M Hyytiäinen, M Gstaiger, ... Journal of Cell Biology 201 (3), 467-484, 2013 | 115 | 2013 |
| Ang‐2 upregulation correlates with increased levels of MMP‐9, VEGF, EPO and TGFβ1 in diabetic eyes undergoing vitrectomy S Loukovaara, A Robciuc, JM Holopainen, K Lehti, T Pessi, J Liinamaa, ... Acta ophthalmologica 91 (6), 531-539, 2013 | 112 | 2013 |
ERIKA GUCCIARDOUniversity of HelsinkiVerified email at helsinki.fi
