| Coexisting liquid phases underlie nucleolar subcompartments M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ... Cell 165 (7), 1686-1697, 2016 | 1619 | 2016 |
| Phase separation in biology; functional organization of a higher order DM Mitrea, RW Kriwacki Cell Communication and Signaling 14, 1-20, 2016 | 671 | 2016 |
| C9orf72 dipeptide repeats impair the assembly, dynamics, and function of membrane-less organelles KH Lee, P Zhang, HJ Kim, DM Mitrea, M Sarkar, BD Freibaum, J Cika, ... Cell 167 (3), 774-788. e17, 2016 | 647 | 2016 |
| Composition-dependent thermodynamics of intracellular phase separation JA Riback, L Zhu, MC Ferrolino, M Tolbert, DM Mitrea, DW Sanders, ... Nature 581 (7807), 209-214, 2020 | 462 | 2020 |
| Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA DM Mitrea, JA Cika, CS Guy, D Ban, PR Banerjee, CB Stanley, A Nourse, ... elife 5, e13571, 2016 | 427 | 2016 |
| Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation DM Mitrea, JA Cika, CB Stanley, A Nourse, PL Onuchic, PR Banerjee, ... Nature communications 9 (1), 842, 2018 | 313 | 2018 |
| Cell cycle regulation by the intrinsically disordered proteins p21 and p27 MK Yoon, DM Mitrea, L Ou, RW Kriwacki Biochemical Society Transactions 40 (5), 981-988, 2012 | 247 | 2012 |
| Structural polymorphism in the N-terminal oligomerization domain of NPM1 DM Mitrea, CR Grace, M Buljan, MK Yun, NJ Pytel, J Satumba, A Nourse, ... Proceedings of the National Academy of Sciences 111 (12), 4466-4471, 2014 | 173 | 2014 |
| C9orf72 Poly (PR) dipeptide repeats disturb biomolecular phase separation and disrupt nucleolar function MR White, DM Mitrea, P Zhang, CB Stanley, DE Cassidy, A Nourse, ... Molecular cell 74 (4), 713-728. e6, 2019 | 148 | 2019 |
| Methods for physical characterization of phase-separated bodies and membrane-less organelles DM Mitrea, B Chandra, MC Ferrolino, EB Gibbs, M Tolbert, MR White, ... Journal of molecular biology 430 (23), 4773-4805, 2018 | 140 | 2018 |
| Modulating biomolecular condensates: a novel approach to drug discovery DM Mitrea, M Mittasch, BF Gomes, IA Klein, MA Murcko Nature Reviews Drug Discovery 21 (11), 841-862, 2022 | 110 | 2022 |
| Disorder-function relationships for the cell cycle regulatory proteins p21 and p27 DM Mitrea, MK Yoon, L Ou, RW Kriwacki Walter de Gruyter 393 (4), 259-274, 2012 | 110 | 2012 |
| Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid–CbpA peptide recombinant fusion protein B Mann, J Thornton, R Heath, KR Wade, RK Tweten, G Gao, K El Kasmi, ... The Journal of infectious diseases 209 (7), 1116-1125, 2014 | 91 | 2014 |
| Compositional adaptability in NPM1-SURF6 scaffolding networks enabled by dynamic switching of phase separation mechanisms MC Ferrolino, DM Mitrea, JR Michael, RW Kriwacki Nature communications 9 (1), 5064, 2018 | 82 | 2018 |
| Regulated unfolding of proteins in signaling DM Mitrea, RW Kriwacki FEBS letters 587 (8), 1081-1088, 2013 | 77 | 2013 |
| Phase separation mediates NUP98 fusion oncoprotein leukemic transformation B Chandra, NL Michmerhuizen, HK Shirnekhi, S Tripathi, BJ Pioso, ... Cancer discovery 12 (4), 1152-1169, 2022 | 72 | 2022 |
| LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation DAAV Clifford Guy, Diana M Mitrea, Po-Chien Chou, Jamshid Temirov, Kate M ... Nature Immunology 23 (5), 757-767, 2022 | 68 | 2022 |
| A Ca2+-Sensing Molecular Switch Based on Alternate Frame Protein Folding MM Stratton, DM Mitrea, SN Loh ACS chemical biology 3 (11), 723-732, 2008 | 60 | 2008 |
| Modular enzyme design: regulation by mutually exclusive protein folding JH Ha, JS Butler, DM Mitrea, SN Loh Journal of molecular biology 357 (4), 1058-1062, 2006 | 49 | 2006 |
| Engineering an artificial zymogen by alternate frame protein folding DM Mitrea, LS Parsons, SN Loh Proceedings of the National Academy of Sciences 107 (7), 2824-2829, 2010 | 41 | 2010 |
