Targeting a ceramide double bond improves insulin resistance and hepatic steatosis B Chaurasia, TS Tippetts, R Mayoral Monibas, J Liu, Y Li, L Wang, ... Science 365 (6451), 386-392, 2019 | 361 | 2019 |
Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis WL Holland, JY Xia, JA Johnson, K Sun, MJ Pearson, AX Sharma, ... Molecular metabolism 6 (3), 267-275, 2017 | 174 | 2017 |
Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle ME Smith, TS Tippetts, ES Brassfield, BJ Tucker, A Ockey, AC Swensen, ... Biochemical Journal 456 (3), 427-439, 2013 | 88 | 2013 |
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis V Panic, S Pearson, J Banks, TS Tippetts, JN Velasco-Silva, S Lee, ... Elife 9, e52558, 2020 | 48 | 2020 |
The ceramide ratio: a predictor of cardiometabolic risk1 TS Tippetts, WL Holland, SA Summers Journal of lipid research 59 (9), 1549-1550, 2018 | 46 | 2018 |
Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration TS Tippetts, DR Winden, AC Swensen, MB Nelson, MO Thatcher, ... BMC cardiovascular disorders 14, 1-9, 2014 | 46 | 2014 |
Ceramides mediate cigarette smoke-induced metabolic disruption in mice MO Thatcher, TS Tippetts, MB Nelson, AC Swensen, DR Winden, ... American Journal of Physiology-Endocrinology and Metabolism 307 (10), E919-E927, 2014 | 40 | 2014 |
Cholesterol–the devil you know; ceramide–the devil you don’t TS Tippetts, WL Holland, SA Summers Trends in pharmacological sciences 42 (12), 1082-1095, 2021 | 39 | 2021 |
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency ARP Verkerke, PJ Ferrara, CT Lin, JM Johnson, TE Ryan, JA Maschek, ... Nature metabolism 1 (9), 876-885, 2019 | 37 | 2019 |
Lipopolysaccharide disrupts mitochondrial physiology in skeletal muscle via disparate effects on sphingolipid metabolism ME Hansen, KJ Simmons, TS Tippetts, MO Thatcher, RR Saito, ... Shock 44 (6), 585-592, 2015 | 33 | 2015 |
Nampt potentiates antioxidant defense in diabetic cardiomyopathy S Oka, J Byun, C Huang, N Imai, G Ralda, P Zhai, X Xu, S Kashyap, ... Circulation research 129 (1), 114-130, 2021 | 30 | 2021 |
Insulin increases ceramide synthesis in skeletal muscle ME Hansen, TS Tippetts, MC Anderson, ZE Holub, ER Moulton, ... Journal of diabetes research 2014, 2014 | 29 | 2014 |
Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice BW Dallon, BA Parker, AE Hodson, TS Tippetts, ME Harrison, ... Biochemical Journal 475 (3), 561-569, 2018 | 24 | 2018 |
Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function AE Hodson, TS Tippetts, BT Bikman Cardiovascular diabetology 14, 1-11, 2015 | 21 | 2015 |
Pharmacological inhibition of TLR4 ameliorates muscle and liver ceramide content after disuse in previously physically active mice AI McKenzie, PT Reidy, DS Nelson, JL Mulvey, NM Yonemura, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2020 | 17 | 2020 |
Ceramide dependent lipotoxicity in metabolic diseases L Ying, TS Tippetts, B Chaurasia Nutrition and healthy aging 5 (1), 1-12, 2019 | 16 | 2019 |
High-mobility group box 1 disrupts metabolic function with cigarette smoke exposure in a ceramide-dependent manner OJ Taylor, MO Thatcher, ST Carr, JL Gibbs, AM Trumbull, ME Harrison, ... International journal of molecular sciences 18 (5), 1099, 2017 | 13 | 2017 |
Structural basis for gating mechanism of the human sodium-potassium pump PT Nguyen, C Deisl, M Fine, TS Tippetts, E Uchikawa, X Bai, B Levine Nature communications 13 (1), 5293, 2022 | 12 | 2022 |
Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis. Mol Metab. 2017; 6 (3): 267–75 WL Holland, JY Xia, JA Johnson, K Sun, MJ Pearson, AX Sharma, ... Epub 2017/03/09. https://doi. org/10.1016/j. molmet. 2017.01. 002 PMID: 28271033, 0 | 10 | |
FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection S Karanth, B Chaurasia, FM Bowman, TS Tippetts, WL Holland, ... Physiological reports 7 (18), e14238, 2019 | 9 | 2019 |