β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression D Hofbauer, D Mougiakakos, L Broggini, M Zaiss, M Büttner-Herold, ... Immunity 54 (8), 1772-1787. e9, 2021 | 60 | 2021 |
Biochemical and biophysical comparison of human and mouse beta‐2 microglobulin reveals the molecular determinants of low amyloid propensity A Achour, L Broggini, X Han, R Sun, C Santambrogio, J Buratto, ... The FEBS Journal 287 (3), 546-560, 2020 | 12 | 2020 |
Glycosylation tunes neuroserpin physiological and pathological properties C Visentin, L Broggini, BM Sala, R Russo, A Barbiroli, C Santambrogio, ... International Journal of Molecular Sciences 21 (9), 3235, 2020 | 11 | 2020 |
Embelin as lead compound for new neuroserpin polymerization inhibitors C Visentin, L Musso, L Broggini, F Bonato, R Russo, C Moriconi, ... Life 10 (7), 111, 2020 | 10 | 2020 |
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution E Scalone, L Broggini, C Visentin, D Erba, F Bačić Toplek, K Peqini, ... Proceedings of the National Academy of Sciences 119 (26), e2203181119, 2022 | 7 | 2022 |
Investigating the molecular basis of the aggregation propensity of the pathological D76N mutant of beta-2 microglobulin: Role of the denatured state L Visconti, F Malagrinò, L Broggini, CMG De Luca, F Moda, S Gianni, ... International Journal of Molecular Sciences 20 (2), 396, 2019 | 6 | 2019 |
l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC … F Ballabio, L Broggini, C Paissoni, X Han, K Peqini, BM Sala, R Sun, ... ACS omega 7 (11), 9622-9635, 2022 | 1 | 2022 |
Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation L Broggini, MM Barzago, V Speranzini, T Schulte, F Sonzini, M Giono, ... Journal of Molecular Biology 435 (24), 168320, 2023 | | 2023 |
beta 2-microglobulin-a trigger for NLRP3 inflammasome activation in tumor-associated macrophages promoting multiple myeloma cell progression C Visentin, D Hofbauer, D Mougiakakos, L Broggini, M Zaiss, ... FEBS OPEN BIO 11, 177-177, 2021 | | 2021 |
MOLECULAR DETERMINANTS UNDERLYING PROTEIN MISFOLDING AND AGGREGATION L Broggini Università degli Studi di Milano, 2021 | | 2021 |
Main Manuscript for Multi-eGO: an in-silico lens to look into protein aggregation kinetics at atomic resolution E Scalone, L Broggini, C Visentin, D Erba, FB Toplek, K Peqini, ... | | |