Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor X Xu, Y Hou, X Yin, L Bao, A Tang, L Song, F Li, S Tsang, K Wu, H Wu, ... Cell 148 (5), 886-895, 2012 | 726 | 2012 |
Genomic and epigenomic profiling of high-risk intestinal metaplasia reveals molecular determinants of progression to gastric cancer KK Huang, K Ramnarayanan, F Zhu, S Srivastava, C Xu, ALK Tan, M Lee, ... Cancer cell 33 (1), 137-150. e5, 2018 | 188 | 2018 |
Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers YA Guo, MM Chang, W Huang, WF Ooi, M Xing, P Tan, AJ Skanderup Nature communications 9 (1), 1520, 2018 | 148 | 2018 |
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... Cancer discovery 7 (11), 1284-1305, 2017 | 131 | 2017 |
Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity WF Ooi, M Xing, C Xu, X Yao, MK Ramlee, MC Lim, F Cao, K Lim, D Babu, ... Nature communications 7 (1), 12983, 2016 | 129 | 2016 |
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements M Muratani, N Deng, WF Ooi, SJ Lin, M Xing, C Xu, A Qamra, ST Tay, ... Nature communications 5 (1), 4361, 2014 | 82 | 2014 |
Cross-species chromatin interactions drive transcriptional rewiring in Epstein–Barr virus–positive gastric adenocarcinoma A Okabe, KK Huang, K Matsusaka, M Fukuyo, M Xing, X Ong, T Hoshii, ... Nature Genetics 52 (9), 919-930, 2020 | 70 | 2020 |
Epigenomic promoter alterations amplify gene isoform and immunogenic diversity in gastric adenocarcinoma A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ... Cancer discovery 7 (6), 630-651, 2017 | 50 | 2017 |
HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis TD Yan, WF Ooi, A Qamra, A Cheung, DL Ma, GM Sundaram, C Xu, ... Nature communications 9 (1), 100, 2018 | 48 | 2018 |
Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma WF Ooi, AM Nargund, KJ Lim, S Zhang, M Xing, A Mandoli, JQ Lim, ... Gut 69 (6), 1039-1052, 2020 | 46 | 2020 |
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer C Xu, WF Ooi, A Qamra, J Tan, BYJ Chua, SWT Ho, K Das, ZFA Isa, Z Li, ... Gut 69 (2), 231-242, 2020 | 33 | 2020 |
Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition R Sundar, KK Huang, V Kumar, K Ramnarayanan, D Demircioglu, Z Her, ... Gut 71 (7), 1277-1288, 2022 | 25 | 2022 |
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer M Xing, WF Ooi, J Tan, A Qamra, PH Lee, Z Li, C Xu, N Padmanabhan, ... The Journal of clinical investigation 130 (6), 3005-3020, 2020 | 15 | 2020 |
Epigenomic promoter alterations amplify gene isoform and immunogenic diversity in gastric adenocarcinoma. Cancer Discov. 2017; 7: 630–651. doi: 10.1158/2159-8290 A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ... CD-16-1022.[Abstract][CrossRef][Google Scholar], 0 | 15 | |
Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation N Padmanabhan, HK Kyon, A Boot, K Lim, S Srivastava, S Chen, Z Wu, ... Genome biology 22, 1-29, 2021 | 14 | 2021 |
VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma. Cancer Discov. 2017; 7: 1284–1305. doi: 10.1158/2159-8290 X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... CD-17-0375.[Abstract][CrossRef][Google Scholar], 0 | 14 | |
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities SWT Ho, T Sheng, M Xing, WF Ooi, C Xu, R Sundar, KK Huang, Z Li, ... Gut 72 (2), 226-241, 2023 | 13 | 2023 |
Chromatin rewiring by mismatch repair protein MSH2 alters cell adhesion pathways and sensitivity to BET inhibition in gastric cancer AM Nargund, C Xu, A Mandoli, A Okabe, GB Chen, KK Huang, T Sheng, ... Cancer Research 82 (14), 2538-2551, 2022 | 8 | 2022 |
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer T Sheng, SWT Ho, WF Ooi, C Xu, M Xing, N Padmanabhan, KK Huang, ... Genome medicine 13, 1-25, 2021 | 8 | 2021 |
Epigenomic consequences of coding and noncoding driver mutations X Yao, M Xing, WF Ooi, P Tan, BT Teh Trends in Cancer 2 (10), 585-605, 2016 | 8 | 2016 |