| Effects of Membrane Lipids on the Activity and Processivity of Purified γ-Secretase O Holmes, S Paturi, W Ye, MS Wolfe, DJ Selkoe Biochemistry-Columbus 51 (17), 3565, 2012 | 140 | 2012 |
| Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains O Holmes, S Pillozzi, JA Deakin, F Carafoli, L Kemp, PJG Butler, M Lyon, ... Journal of molecular biology 367 (2), 395-408, 2007 | 118 | 2007 |
| Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions PV Borre, AB Schrock, PM Anderson, JC Morris, AM Heilmann, O Holmes, ... The Oncologist 22 (3), 255-263, 2017 | 69 | 2017 |
| Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist M Youles, O Holmes, MV Petoukhov, MA Nessen, S Stivala, DI Svergun, ... Journal of molecular biology 377 (3), 616-622, 2008 | 60 | 2008 |
| The stress response neuropeptide CRF increases amyloid‐β production by regulating γ‐secretase activity HJ Park, Y Ran, JI Jung, O Holmes, AR Price, L Smithson, ... The EMBO journal 34 (12), 1674-1686, 2015 | 54 | 2015 |
| BRCA2 Reversion Mutation Associated With Acquired Resistance to Olaparib in Estrogen Receptor-positive Breast Cancer Detected by Genomic Profiling of Tissue and Liquid Biopsy EL Gornstein, S Sandefur, JH Chung, LM Gay, O Holmes, RL Erlich, ... Clinical breast cancer 18 (2), 184-188, 2018 | 40 | 2018 |
| Pen-2 is essential for γ-secretase complex stability and trafficking but partially dispensable for endoproteolysis O Holmes, S Paturi, DJ Selkoe, MS Wolfe Biochemistry 53 (27), 4393-4406, 2014 | 37 | 2014 |
| Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion V Subbiah, O Holmes, K Gowen, D Spritz, B Amini, WL Wang, AB Schrock, ... Oncology 91 (6), 348-353, 2016 | 31 | 2016 |
| Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis R Sinha Roy, S Soni, R Harfouche, PR Vasudevan, O Holmes, ... Proceedings of the National Academy of Sciences 107 (31), 13608-13613, 2010 | 31 | 2010 |
| Biomarkers in breast cancer: An integrated analysis of comprehensive genomic profiling and Pd‐L1 immunohistochemistry biomarkers in 312 patients with breast cancer RSP Huang, X Li, J Haberberger, E Sokol, E Severson, DL Duncan, ... The oncologist 25 (11), 943-953, 2020 | 19 | 2020 |
| Landscape of biomarkers in non-small cell lung cancer using comprehensive genomic profiling and PD-L1 immunohistochemistry RSP Huang, E Severson, J Haberberger, DL Duncan, A Hemmerich, ... Pathology and Oncology Research 27, 592997, 2021 | 16 | 2021 |
| First results of the EORTC-SPECTA/Arcagen study exploring the genomics of rare cancers in collaboration with the European reference network EURACAN M Morfouace, A Stevovic, M Vinches, V Golfinopoulos, DX Jin, O Holmes, ... ESMO open 5 (6), e001075, 2020 | 16 | 2020 |
| Hidradenitis suppurativa: haploinsufficiency of gamma‐secretase components does not affect gamma‐secretase enzyme activity in vitro AE Pink, D Dafou, N Desai, O Holmes, C Hobbs, CH Smith, P Mortimer, ... British Journal of Dermatology 175 (3), 632-635, 2016 | 14 | 2016 |
| Clinicopathologic and genomic characterization of PD‐L1 positive urothelial carcinomas RSP Huang, J Haberberger, L Harries, E Severson, DL Duncan, ... The Oncologist 26 (5), 375-382, 2021 | 9 | 2021 |
| Functional analysis and purification of a Pen‐2 fusion protein for γ‐secretase structural studies O Holmes, S Paturi, MS Wolfe, DJ Selkoe Journal of neurochemistry 131 (1), 94-100, 2014 | 7 | 2014 |
| Hidradenitis suppurativa: Haploinsufficiency of the gamma-secretase components NCSTN and PSENEN does not affect gamma-secretase enzyme activity in vitro AE Pink, D Dafou, N Desai, O Holmes, C Smith, P Mortimer, MA Simpson, ... JOURNAL OF INVESTIGATIVE DERMATOLOGY 134, S54-S54, 2014 | 1 | 2014 |
| O2‐06‐03: CAN WE TARGET CORTICOTROPIN RELEASING FACTOR (CRF) FOR THERAPEUTIC BENEFIT IN AD? KM Felsenstein, HJ Park, Y Ran, JI Jung, O Holmes, L Smithson, ... Alzheimer's & Dementia 10, P175-P175, 2014 | | 2014 |
| Hidradenitis suppurativa: haploinsufficiency of gamma-secretase components does not affect gamma-secretase enzyme activity in vitro A Pink, D Dafou, N Desai, O Holmes, C Smith, P Mortimer, M Simpson, ... BRITISH JOURNAL OF DERMATOLOGY 170 (4), E36-E37, 2014 | | 2014 |
