A small-molecule inhibitor of Lin28 M Roos, U Pradère, RP Ngondo, A Behera, S Allegrini, G Civenni, ... ACS chemical biology 11 (10), 2773-2781, 2016 | 154 | 2016 |
Stereochemical bias introduced during RNA synthesis modulates the activity of phosphorothioate siRNAs H Jahns, M Roos, J Imig, F Baumann, Y Wang, R Gilmour, J Hall Nature communications 6 (1), 6317, 2015 | 105 | 2015 |
Activation of the Lin28/let-7 axis by loss of ESE3/EHF promotes a tumorigenic and stem-like phenotype in prostate cancer D Albino, G Civenni, C Dallavalle, M Roos, H Jahns, L Curti, S Rossi, ... Cancer research 76 (12), 3629-3643, 2016 | 89 | 2016 |
Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF-α B Guennewig, M Roos, AM Dogar, LFR Gebert, JA Zagalak, V Vongrad, ... Rna 20 (1), 61-75, 2014 | 61 | 2014 |
Chemical Synthesis of Mono‐and Bis‐Labeled Pre‐MicroRNAs U Pradère, A Brunschweiger, LFR Gebert, M Lucic, M Roos, J Hall Angewandte Chemie International Edition, 12028-12032, 2013 | 40 | 2013 |
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells M Roos, MAE Rebhan, M Lucic, D Pavlicek, U Pradere, H Towbin, ... Nucleic acids research 43 (2), e9-e9, 2015 | 32 | 2015 |
PTPσ inhibitors promote hematopoietic stem cell regeneration Y Zhang, M Roos, H Himburg, CM Termini, M Quarmyne, M Li, L Zhao, ... Nature communications 10 (1), 3667, 2019 | 31 | 2019 |
A small molecule screen to identify regulators of let-7 targets J Cinkornpumin, M Roos, L Nguyen, X Liu, X Gaeta, S Lin, DN Chan, ... Scientific reports 7 (1), 15973, 2017 | 23 | 2017 |
Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution CM Termini, A Pang, T Fang, M Roos, VY Chang, Y Zhang, NJ Setiawan, ... Nature Communications 12 (1), 6990, 2021 | 16 | 2021 |
Epidermal growth factor receptor–dependent DNA repair promotes murine and human hematopoietic regeneration T Fang, Y Zhang, VY Chang, M Roos, CM Termini, L Signaevskaia, ... Blood, The Journal of the American Society of Hematology 136 (4), 441-454, 2020 | 14 | 2020 |
Wild-type Kras expands and exhausts hematopoietic stem cells JP Sasine, HA Himburg, CM Termini, M Roos, E Tran, L Zhao, J Kan, M Li, ... JCI insight 3 (11), 2018 | 14 | 2018 |
Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling HA Himburg, M Roos, T Fang, Y Zhang, CM Termini, L Schlussel, M Kim, ... The Journal of clinical investigation 130 (1), 315-328, 2020 | 10 | 2020 |
Pharmacologic Targeting of LIN28/Let-7 in Acute Myeloid Leukemia MM Roos, M Li, P Amara, JP Chute Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 4 | 2018 |
Epidermal Growth Factor Receptor-Mediated DNA Repair Regulates Hematopoietic Stem Cell Regeneration T Fang, HA Himburg, MM Roos, Y Zhang, J Kan, L Zhao, JP Chute Blood 132, 638, 2018 | 2 | 2018 |
Inhibition of semaphorin 3A signaling promotes regeneration of hematopoietic stem cells and their bone marrow vascular niche JP Chute, C Termini, L Schlussel, MM Roos, J Kan, J Sasine, T Fang, ... Blood 132, 1292, 2018 | 1 | 2018 |
Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling HA Himburg, M Roos, T Fang J Clin Invest 129061, 2009 | 1 | 2009 |
Inhibitors of lin28 and methods of use thereof M Roos, ME Jung, HJ Gim US Patent App. 17/786,764, 2023 | | 2023 |
Inhibitors of lin28 and methods of use thereof M Roos, ME Jung, HJ Gim | | 2021 |
Compounds and methods for hematopoietic regeneration JP Chute, ME Jung, E Diers, HJ Gim, M Roos US Patent App. 16/767,919, 2021 | | 2021 |
Grb10 is a tumor suppressor in acute myeloid leukemia M Roos, W Chai-Ho, M Li, P Lin Experimental Hematology 76, S83, 2019 | | 2019 |