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Martina  Roos
Martina Roos
Sardona Therapeutics
Verified email at sardonatx.com
Title
Cited by
Cited by
Year
A small-molecule inhibitor of Lin28
M Roos, U Pradère, RP Ngondo, A Behera, S Allegrini, G Civenni, ...
ACS chemical biology 11 (10), 2773-2781, 2016
1542016
Stereochemical bias introduced during RNA synthesis modulates the activity of phosphorothioate siRNAs
H Jahns, M Roos, J Imig, F Baumann, Y Wang, R Gilmour, J Hall
Nature communications 6 (1), 6317, 2015
1052015
Activation of the Lin28/let-7 axis by loss of ESE3/EHF promotes a tumorigenic and stem-like phenotype in prostate cancer
D Albino, G Civenni, C Dallavalle, M Roos, H Jahns, L Curti, S Rossi, ...
Cancer research 76 (12), 3629-3643, 2016
892016
Synthetic pre-microRNAs reveal dual-strand activity of miR-34a on TNF-α
B Guennewig, M Roos, AM Dogar, LFR Gebert, JA Zagalak, V Vongrad, ...
Rna 20 (1), 61-75, 2014
612014
Chemical Synthesis of Mono‐and Bis‐Labeled Pre‐MicroRNAs
U Pradère, A Brunschweiger, LFR Gebert, M Lucic, M Roos, J Hall
Angewandte Chemie International Edition, 12028-12032, 2013
402013
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells
M Roos, MAE Rebhan, M Lucic, D Pavlicek, U Pradere, H Towbin, ...
Nucleic acids research 43 (2), e9-e9, 2015
322015
PTPσ inhibitors promote hematopoietic stem cell regeneration
Y Zhang, M Roos, H Himburg, CM Termini, M Quarmyne, M Li, L Zhao, ...
Nature communications 10 (1), 3667, 2019
312019
A small molecule screen to identify regulators of let-7 targets
J Cinkornpumin, M Roos, L Nguyen, X Liu, X Gaeta, S Lin, DN Chan, ...
Scientific reports 7 (1), 15973, 2017
232017
Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution
CM Termini, A Pang, T Fang, M Roos, VY Chang, Y Zhang, NJ Setiawan, ...
Nature Communications 12 (1), 6990, 2021
162021
Epidermal growth factor receptor–dependent DNA repair promotes murine and human hematopoietic regeneration
T Fang, Y Zhang, VY Chang, M Roos, CM Termini, L Signaevskaia, ...
Blood, The Journal of the American Society of Hematology 136 (4), 441-454, 2020
142020
Wild-type Kras expands and exhausts hematopoietic stem cells
JP Sasine, HA Himburg, CM Termini, M Roos, E Tran, L Zhao, J Kan, M Li, ...
JCI insight 3 (11), 2018
142018
Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling
HA Himburg, M Roos, T Fang, Y Zhang, CM Termini, L Schlussel, M Kim, ...
The Journal of clinical investigation 130 (1), 315-328, 2020
102020
Pharmacologic Targeting of LIN28/Let-7 in Acute Myeloid Leukemia
MM Roos, M Li, P Amara, JP Chute
Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018
42018
Epidermal Growth Factor Receptor-Mediated DNA Repair Regulates Hematopoietic Stem Cell Regeneration
T Fang, HA Himburg, MM Roos, Y Zhang, J Kan, L Zhao, JP Chute
Blood 132, 638, 2018
22018
Inhibition of semaphorin 3A signaling promotes regeneration of hematopoietic stem cells and their bone marrow vascular niche
JP Chute, C Termini, L Schlussel, MM Roos, J Kan, J Sasine, T Fang, ...
Blood 132, 1292, 2018
12018
Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling
HA Himburg, M Roos, T Fang
J Clin Invest 129061, 2009
12009
Inhibitors of lin28 and methods of use thereof
M Roos, ME Jung, HJ Gim
US Patent App. 17/786,764, 2023
2023
Inhibitors of lin28 and methods of use thereof
M Roos, ME Jung, HJ Gim
2021
Compounds and methods for hematopoietic regeneration
JP Chute, ME Jung, E Diers, HJ Gim, M Roos
US Patent App. 16/767,919, 2021
2021
Grb10 is a tumor suppressor in acute myeloid leukemia
M Roos, W Chai-Ho, M Li, P Lin
Experimental Hematology 76, S83, 2019
2019
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