Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis N Verma, Y Vinik, A Saroha, NU Nair, E Ruppin, G Mills, T Karn, V Dubey, ... Science advances 6 (34), eaba8968, 2020 | 96 | 2020 |
Proteomic analysis of circulating extracellular vesicles identifies potential markers of breast cancer progression, recurrence, and response Y Vinik, FG Ortega, GB Mills, Y Lu, M Jurkowicz, S Halperin, M Aharoni, ... Science advances 6 (40), eaba5714, 2020 | 70 | 2020 |
The mammalian lectin galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice Y Vinik, H Shatz-Azoulay, A Vivanti, N Hever, Y Levy, R Karmona, ... Elife 4, e05914, 2015 | 58 | 2015 |
Prolonged insulin treatment sensitizes apoptosis pathways in pancreatic β cells E Bucris, A Beck, S Boura-Halfon, R Isaac, Y Vinik, T Rosenzweig, ... J Endocrinol 230 (3), 291-307, 2016 | 28 | 2016 |
The animal lectin galectin-8 promotes cytokine expression and metastatic tumor growth in mice H Shatz-Azoulay, Y Vinik, R Isaac, U Kohler, S Lev, Y Zick Scientific reports 10 (1), 7375, 2020 | 27 | 2020 |
Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets A Beck, Y Vinik, H Shatz-Azoulay, R Isaac, S Streim, G Jona, ... Diabetologia 56 (6), 1317-1326, 2013 | 26 | 2013 |
Differential cellular responses to adhesive interactions with galectin-8-and fibronectin-coated substrates W Li, A Sancho, WL Chung, Y Vinik, J Groll, Y Zick, O Medalia, ... Journal of Cell Science 134 (8), jcs252221, 2021 | 21 | 2021 |
Mouse modeling dissecting macrophage–breast cancer communication uncovered roles of PYK2 in macrophage recruitment and breast tumorigenesis A Müller, UA Köhler, S Trzebanski, Y Vinik, HM Raj, J Girault, ... Advanced Science 9 (9), 2105696, 2022 | 18 | 2022 |
Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists B Patel, C Kishor, TA Houston, H Shatz-Azoulay, Y Zick, Y Vinik, ... Journal of Medicinal Chemistry 63 (20), 11573-11584, 2020 | 18 | 2020 |
Ablation of the mammalian lectin galectin‐8 induces bone defects in mice Y Vinik, H Shatz‐Azoulay, S Hiram‐Bab, L Kandel, Y Gabet, G Rivkin, ... The FASEB Journal 32 (5), 2366-2380, 2018 | 18 | 2018 |
Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance F Lamballe, F Ahmad, Y Vinik, O Castellanet, F Daian, AK Müller, ... Advanced Science, 2003049, 2020 | 16 | 2020 |
Structure‐Based Design of a Monosaccharide Ligand Targeting Galectin‐8 MH Bohari, X Yu, C Kishor, B Patel, RM Go, HA Eslampanah Seyedi, ... ChemMedChem 13 (16), 1664-1672, 2018 | 16 | 2018 |
Molecular mechanisms underlying the role of galectin-8 as a regulator of cancer growth and metastasis Y Vinik, H Shatz-Azoulay, Y Zick Trends in Glycoscience and Glycotechnology 30 (172), SE119-SE128, 2018 | 16 | 2018 |
The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC L Khera, Y Vinik, F Maina, S Lev Life science alliance 4 (6), 2021 | 9 | 2021 |
BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators O Castellanet, F Ahmad, Y Vinik, GB Mills, B Habermann, JP Borg, S Lev, ... Theranostics 11 (19), 9180-9197, 2021 | 4 | 2021 |
Prolonged elimination of negative feedback control mechanisms along the insulin signaling pathway impairs β-cell function in vivo R Isaac, Y Vinik, S Boura-Halfon, L Farack, S Streim, E Elhanany, Z Kam, ... Diabetes 66 (7), 1879-1889, 2017 | 4 | 2017 |
Nedd4 family interacting protein 1 (Ndfip1) promotes death of pancreatic beta cells A Beck, H Shatz-Azoulay, Y Vinik, R Isaac, S Boura-Halfon, Y Zick Biochemical and Biophysical Research Communications 465 (4), 851-856, 2015 | 3 | 2015 |
A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing R Isaac, Y Vinik, M Mikl, S Nadav-Eliyahu, H Shatz-Azoulay, A Yaakobi, ... Iscience 25 (11), 2022 | 1 | 2022 |
Programming a Ferroptosis‐to‐Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy Y Vinik, A Maimon, V Dubey, H Raj, I Abramovitch, S Malitsky, M Itkin, ... Advanced Science, 2307263, 2024 | | 2024 |
Method of diagnosing breast cancer S Lev, Y Vinik, FG Ortega, M GUTMAN US Patent App. 18/128,260, 2023 | | 2023 |