| Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain JD Osteen, V Herzig, J Gilchrist, JJ Emrick, C Zhang, X Wang, J Castro, ... Nature 534 (7608), 494-499, 2016 | 276 | 2016 |
| Visceral pain L Grundy, A Erickson, SM Brierley Annual review of physiology 81, 261-284, 2019 | 195 | 2019 |
| Pain in endometriosis J Maddern, L Grundy, J Castro, SM Brierley Frontiers in cellular neuroscience 14, 590823, 2020 | 157 | 2020 |
| Mechanisms underlying overactive bladder and interstitial cystitis/painful bladder syndrome L Grundy, A Caldwell, SM Brierley Frontiers in neuroscience 12, 424031, 2018 | 109 | 2018 |
| α-Conotoxin Vc1. 1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors J Castro, AM Harrington, S Garcia-Caraballo, J Maddern, L Grundy, ... Gut 66 (6), 1083-1094, 2017 | 91 | 2017 |
| Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1 MC Inserra, MR Israel, A Caldwell, J Castro, JR Deuis, AM Harrington, ... Scientific reports 7 (1), 42810, 2017 | 83 | 2017 |
| Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), 2019 | 67 | 2019 |
| Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction L Grundy, AM Harrington, J Castro, S Garcia-Caraballo, A Deiteren, ... JCI insight 3 (19), 2018 | 65 | 2018 |
| Cross-organ sensitization between the colon and bladder: to pee or not to pee? L Grundy, SM Brierley American Journal of Physiology-Gastrointestinal and Liver Physiology 314 (3 …, 2018 | 63 | 2018 |
| Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1 L Grundy, A Caldwell, SG Caraballo, A Erickson, G Schober, J Castro, ... American Journal of Physiology-Renal Physiology, 2020 | 55 | 2020 |
| Contribution of membrane receptor signalling to chronic visceral pain M Sadeghi, A Erickson, J Castro, A Deiteren, AM Harrington, L Grundy, ... The international journal of biochemistry & cell biology 98, 10-23, 2018 | 44 | 2018 |
| Voltage‐gated sodium channels: (NaV)igating the field to determine their contribution to visceral nociception A Erickson, A Deiteren, AM Harrington, S Garcia‐Caraballo, J Castro, ... The Journal of physiology 596 (5), 785-807, 2018 | 43 | 2018 |
| NaV1. 1 inhibition can reduce visceral hypersensitivity J Salvatierra, J Castro, A Erickson, Q Li, J Braz, J Gilchrist, L Grundy, ... JCI insight 3 (11), 2018 | 41 | 2018 |
| Cyclic analogues of α‐conotoxin Vc1. 1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain J Castro, L Grundy, A Deiteren, AM Harrington, T O'Donnell, J Maddern, ... British journal of pharmacology 175 (12), 2384-2398, 2018 | 39 | 2018 |
| TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder L Grundy, DM Daly, C Chapple, D Grundy, R Chess-Williams Scientific reports 8 (1), 197, 2018 | 39 | 2018 |
| Identifying unique subtypes of spinal afferent nerve endings within the urinary bladder of mice NJ Spencer, S Greenheigh, M Kyloh, TJ Hibberd, H Sharma, L Grundy, ... Journal of Comparative Neurology 526 (4), 707-720, 2018 | 37 | 2018 |
| Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord AM Harrington, SG Caraballo, JE Maddern, L Grundy, J Castro, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 317 (3 …, 2019 | 33 | 2019 |
| A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome FC Cardoso, J Castro, L Grundy, G Schober, S Garcia-Caraballo, T Zhao, ... Pain 162 (2), 569-581, 2021 | 32 | 2021 |
| Tetrodotoxin-sensitive voltage-gated sodium channels regulate bladder afferent responses to distension L Grundy, A Erickson, A Caldwell, S Garcia-Caraballo, G Rychkov, ... Pain 159 (12), 2573-2584, 2018 | 32 | 2018 |
| Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk P Ge, J Ren, AM Harrington, L Grundy, J Castro, SM Brierley, G Hannig Pain 160 (11), 2566-2579, 2019 | 29 | 2019 |
Stuart M. BrierleyDirector, Visceral Pain Group & Hopwood Centre for Neurobiology. Co-leader Lifelong Health, SAHMRIVerified email at sahmri.com
