| Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart. GS Liu, J Thornton, DM Van Winkle, AW Stanley, RA Olsson, JM Downey Circulation 84 (1), 350-356, 1991 | 1795 | 1991 |
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| Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways XM Yang, JB Proctor, L Cui, T Krieg, JM Downey, MV Cohen Journal of the American College of Cardiology 44 (5), 1103-1110, 2004 | 934 | 2004 |
| Opening of Mitochondrial KATP Channels Triggers the Preconditioned State by Generating Free Radicals T Pain, XM Yang, SD Critz, Y Yue, A Nakano, GS Liu, G Heusch, ... Circulation research 87 (6), 460-466, 2000 | 922 | 2000 |
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| Preconditioning protects ischemic rabbit heart by protein kinase C activation K Ytrehus, Y Liu, JM Downey American Journal of Physiology-Heart and Circulatory Physiology 266 (3 …, 1994 | 885 | 1994 |
| Ischemic Preconditioning: From Adenosine Receptor to KATP Channel MV Cohen, CP Baines, JM Downey Annual review of physiology 62 (1), 79-109, 2000 | 707 | 2000 |
| Role of bradykinin in protection of ischemic preconditioning in rabbit hearts M Goto, Y Liu, XM Yang, JL Ardell, MV Cohen, JM Downey Circulation research 77 (3), 611-621, 1995 | 695 | 1995 |
| Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium CP Baines, M Goto, JM Downey Journal of molecular and cellular cardiology 29 (1), 207-216, 1997 | 647 | 1997 |
| Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. JD Thornton, GS Liu, RA Olsson, JM Downey Circulation 85 (2), 659-665, 1992 | 608 | 1992 |
| The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis MV Cohen, XM Yang, JM Downey Circulation 115 (14), 1895-1903, 2007 | 551* | 2007 |
| Ischemic preconditioning protects against infarction in rat heart Y Liu, JM Downey American Journal of Physiology-Heart and Circulatory Physiology 263 (4 …, 1992 | 536 | 1992 |
| Signaling pathways in ischemic preconditioning JM Downey, AM Davis, MV Cohen Heart failure reviews 12, 181-188, 2007 | 485 | 2007 |
| Preconditioning: state of the art myocardial protection CS Lawson, JM Downey Cardiovascular research 27 (4), 542-550, 1993 | 477 | 1993 |
| Inhibition of coronary blood flow by a vascular waterfall mechanism. JM Downey, ES Kirk Circulation research 36 (6), 753-760, 1975 | 466 | 1975 |
| Volatile anesthetics protect the ischemic rabbit myocardium from infarction DK Cope, KW Impastato, MV Cohen, JM Downey The Journal of the American Society of Anesthesiologists 86 (3), 699-709, 1997 | 465 | 1997 |
| Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits. MV Cohen, GS Liu, JM Downey Circulation 84 (1), 341-349, 1991 | 452 | 1991 |
| Signal transduction of ischemic preconditioning R Schulz, MV Cohen, M Behrends, JM Downey, G Heusch Cardiovascular research 52 (2), 181-198, 2001 | 421 | 2001 |
| Postconditioning’s protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3–kinase and guanylyl cyclase activation XM Yang, S Philipp, JM Downey, MV Cohen Basic research in cardiology 100, 57-63, 2005 | 419 | 2005 |
| Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial KATP channels MV Cohen, XM Yang, GS Liu, G Heusch, JM Downey Circulation research 89 (3), 273-278, 2001 | 419 | 2001 |
