| Varenicline: an α4β2 nicotinic receptor partial agonist for smoking cessation JW Coe, PR Brooks, MG Vetelino, MC Wirtz, EP Arnold, J Huang, ... Journal of medicinal chemistry 48 (10), 3474-3477, 2005 | 1159 | 2005 |
| Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid H Rollema, LK Chambers, JW Coe, J Glowa, RS Hurst, LA Lebel, Y Lu, ... Neuropharmacology 52 (3), 985-994, 2007 | 644 | 2007 |
| CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. DW Schulz, RS Mansbach, J Sprouse, JP Braselton, J Collins, M Corman, ... Proceedings of the National Academy of Sciences 93 (19), 10477-10482, 1996 | 422 | 1996 |
| Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia CJ Schmidt, DS Chapin, J Cianfrogna, ML Corman, M Hajos, JF Harms, ... Journal of Pharmacology and Experimental Therapeutics 325 (2), 681-690, 2008 | 326 | 2008 |
| Pre‐clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence H Rollema, A Shrikhande, KM Ward, FD Tingley Iii, JW Coe, BT O'Neill, ... British journal of pharmacology 160 (2), 334-345, 2010 | 181 | 2010 |
| 3, 5-Bicyclic aryl piperidines: A novel class of α4β2 neuronal nicotinic receptor partial agonists for smoking cessation JW Coe, PR Brooks, MC Wirtz, CG Bashore, KE Bianco, MG Vetelino, ... Bioorganic & Medicinal Chemistry Letters 15 (22), 4889-4897, 2005 | 116 | 2005 |
| In pursuit of α4β2 nicotinic receptor partial agonists for smoking cessation: Carbon analogs of (−)-cytisine JW Coe, MG Vetelino, CG Bashore, MC Wirtz, PR Brooks, EP Arnold, ... Bioorganic & medicinal chemistry letters 15 (12), 2974-2979, 2005 | 85 | 2005 |
| Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo RJ Kleiman, DS Chapin, C Christoffersen, J Freeman, KR Fonseca, ... Journal of Pharmacology and Experimental Therapeutics 341 (2), 396-409, 2012 | 81 | 2012 |
| 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists YL Chen, RS Obach, J Braselton, ML Corman, J Forman, J Freeman, ... Journal of medicinal chemistry 51 (5), 1385-1392, 2008 | 72 | 2008 |
| Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists YL Chen, J Braselton, J Forman, RJ Gallaschun, R Mansbach, ... Journal of medicinal chemistry 51 (5), 1377-1384, 2008 | 50 | 2008 |
| The discovery of a structurally novel class of inhibitors of the type 1 glycine transporter JA Lowe III, X Hou, C Schmidt, FD Tingley III, S McHardy, M Kalman, ... Bioorganic & medicinal chemistry letters 19 (11), 2974-2976, 2009 | 45 | 2009 |
| 1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of Psychosis L Zhang, MA Brodney, J Candler, AC Doran, AJ Duplantier, IV Efremov, ... Journal of medicinal chemistry 54 (6), 1724-1739, 2011 | 43 | 2011 |
| P-glycoprotein efflux at the blood-brain barrier mediates differences in brain disposition and pharmacodynamics between two structurally related neurokinin-1 receptor antagonists BJ Smith, AC Doran, S McLean, FD Tingley, BT O'Neill, SM Kajiji Journal of Pharmacology and Experimental Therapeutics 298 (3), 1252-1259, 2001 | 43 | 2001 |
| Modulation of NMDA receptor function by inhibition of D-amino acid oxidase in rodent brain CA Strick, C Li, L Scott, B Harvey, M Hajós, SJ Steyn, MA Piotrowski, ... Neuropharmacology 61 (5-6), 1001-1015, 2011 | 42 | 2011 |
| Development and validation of a sample stabilization strategy and a UPLC–MS/MS method for the simultaneous quantitation of acetylcholine (ACh), histamine (HA), and its … Y Zhang, FD Tingley III, E Tseng, M Tella, X Yang, E Groeber, J Liu, W Li, ... Journal of Chromatography B 879 (22), 2023-2033, 2011 | 41 | 2011 |
| Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension FD Tingley III, SP Arnerić Brain research 537 (1-2), 175-181, 1990 | 36 | 1990 |
| The neurokinin‐1 antagonist activity of maropitant, an antiemetic drug for dogs, in a gerbil model V de la Puente‐Redondo, FD TINGLEY III, RP Schneider, MA Hickman Journal of veterinary pharmacology and therapeutics 30 (4), 281-287, 2007 | 32 | 2007 |
| Application of neurophysiological biomarkers for Huntington's disease: evaluating a phosphodiesterase 9A inhibitor D Nagy, FD Tingley III, M Stoiljkovic, M Hajós Experimental Neurology 263, 122-131, 2015 | 21 | 2015 |
| An octahydro-cyclopenta [c] pyrrole series of inhibitors of the type 1 glycine transporter JA Lowe III, SL DeNinno, SE Drozda, CJ Schmidt, KM Ward, FD Tingley III, ... Bioorganic & medicinal chemistry letters 20 (3), 907-911, 2010 | 14 | 2010 |
| P2‐241: PDE9A‐mediated regulation of cGMP: Developing a biomarker for a novel therapy for Alzheimer's disease CJ Schmidt, JF Harms, FD Tingley, K Schmidt, WO Adamowicz, ... Alzheimer's & Dementia 5 (4S_Part_11), P331-P331, 2009 | 14 | 2009 |
Mihaly HajosProfessor Adjunct, Yale University School of MedicineVerified email at yale.edu
