Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression GM Kapler, CM Coburn, SM Beverley Molecular and cellular biology, 1990 | 488 | 1990 |
The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor. DD Moore, AR Marks, DI Buckley, G Kapler, F Payvar, HM Goodman Proceedings of the National Academy of Sciences 82 (3), 699-702, 1985 | 275 | 1985 |
Functional genomics: the coming of age for Tetrahymena thermophila AP Turkewitz, E Orias, G Kapler Trends in genetics 18 (1), 35-40, 2002 | 144 | 2002 |
Impaired replication elongation in Tetrahymena mutants deficient in histone H3 Lys 27 monomethylation S Gao, J Xiong, C Zhang, BR Berquist, R Yang, M Zhao, AJ Molascon, ... Genes & development 27 (15), 1662-1679, 2013 | 73 | 2013 |
Tetrahymena ORC contains a ribosomal RNA fragment that participates in rDNA origin recognition MM Mohammad, TR Donti, J Sebastian Yakisich, AG Smith, GM Kapler The EMBO Journal 26 (24), 5048-5060, 2007 | 59 | 2007 |
Transient and stable DNA transformation of Tetrahymena thermophila by electroporation J Gaertig, G Kapler Methods in cell biology 62, 485-500, 1999 | 57 | 1999 |
Developmentally regulated processing and replication of the Tetrahymena rDNA minichromosome. GM Kapler Current opinion in genetics & development 3 (5), 730-735, 1993 | 56 | 1993 |
Transcriptional mapping of the amplified region encoding the dihydrofolate reductase-thymidylate synthase of Leishmania major reveals a high density of transcripts, including … GM Kapler, SM Beverley Molecular and cellular biology, 1989 | 56 | 1989 |
A germline-limited piggyBac transposase gene is required for precise excision in Tetrahymena genome rearrangement L Feng, G Wang, EP Hamilton, J Xiong, G Yan, K Chen, X Chen, W Dui, ... Nucleic Acids Research 45 (16), 9481-9502, 2017 | 50 | 2017 |
Developmental Regulation of DNA Replication: Replication Fork Barriers and Programmed Gene Amplification in Tetrahymena thermophila Z Zhang, DM Macalpine, DM Kapler Molecular and cellular biology 17 (10), 6147-6156, 1997 | 50 | 1997 |
Nuclease mapping and DNA sequence analysis of transcripts from the dihydrofolate reductase-thymidylate synthase (R) region of Leishmania major GM Kapler, K Zhang, SM Beverley Nucleic acids research 18 (21), 6399-6408, 1990 | 49 | 1990 |
A weak germ-line excision mutation blocks developmentally controlled amplification of the rDNA minichromosome of Tetrahymena thermophila. GM Kapler, EH Blackburn Genes & development 8 (1), 84-95, 1994 | 38 | 1994 |
A β-Tubulin Mutation Selectively Uncouples Nuclear Division and Cytokinesis in Tetrahymena thermophila JJ Smith, JS Yakisich, GM Kapler, ES Cole, DP Romero Eukaryotic Cell 3 (5), 1217-1226, 2004 | 36 | 2004 |
Type I elements mediate replication fork pausing at conserved upstream sites in the Tetrahymena thermophila ribosomal DNA minichromosome DM MacAlpine, Z Zhang, GM Kapler Molecular and cellular biology, 1997 | 36 | 1997 |
Sequence and S1 nuclease mapping of the 5′ region of the dihydrofolate reductase—thymidylate synthase gene of Leishmania major GM Kapler, K Zhang, SM Beverley Nucleic acids research 15 (8), 3369-3383, 1987 | 33 | 1987 |
The effect of phosphoinositide 3-kinase inhibitors on programmed nuclear degradation in Tetrahymena and fate of surviving nuclei JS Yakisich, GM Kapler Cell Death & Differentiation 11 (10), 1146-1149, 2004 | 27 | 2004 |
Transient activation of the Hedgehog-Gli pathway rescues radiotherapy-induced dry mouth via recovering salivary gland resident macrophages Q Zhao, L Zhang, B Hai, J Wang, CL Baetge, MA Deveau, GM Kapler, ... Cancer research 80 (24), 5531-5542, 2020 | 26 | 2020 |
Differential targeting of Tetrahymena ORC to ribosomal DNA and non‐rDNA replication origins TR Donti, S Datta, PY Sandoval, GM Kapler The EMBO Journal 28 (3), 223-233, 2009 | 24 | 2009 |
TIF1 Activates the Intra-S-Phase Checkpoint Response in the Diploid Micronucleus and Amitotic Polyploid Macronucleus of Tetrahymena JS Yakisich, PY Sandoval, TL Morrison, GM Kapler Molecular biology of the cell 17 (12), 5185-5197, 2006 | 23 | 2006 |
TIF1 Represses rDNA Replication Initiation, but Promotes Normal S Phase Progression and Chromosome Transmission in Tetrahymena TL Morrison, JS Yakisich, D Cassidy-Hanley, GM Kapler Molecular biology of the cell 16 (6), 2624-2635, 2005 | 23 | 2005 |