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Kenneth K Chan
Kenneth K Chan
Emeritus Professor of Pharmaceutics and Internal Medicine, The Ohio State University, Columbus, Ohio
Verified email at osu.edu
Title
Cited by
Cited by
Year
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
M Fabbri, R Garzon, A Cimmino, Z Liu, N Zanesi, E Callegari, S Liu, ...
Proceedings of the National Academy of Sciences 104 (40), 15805-15810, 2007
20002007
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly …
R Garzon, S Liu, M Fabbri, Z Liu, CEA Heaphy, E Callegari, S Schwind, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6411-6418, 2009
9162009
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms
V Sandor, S Bakke, RW Robey, MH Kang, MV Blagosklonny, J Bender, ...
Clinical Cancer Research 8 (3), 718-728, 2002
6852002
Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine
W Blum, R Garzon, RB Klisovic, S Schwind, A Walker, S Geyer, S Liu, ...
Proceedings of the National Academy of Sciences 107 (16), 7473-7478, 2010
5892010
A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia
JC Byrd, G Marcucci, MR Parthun, JJ Xiao, RB Klisovic, M Moran, TS Lin, ...
Blood 105 (3), 959-967, 2005
4812005
Recent developments in the maytansinoid antitumor agents
JM Cassady, KK Chan, HG Floss, E Leistner
Chemical and Pharmaceutical Bulletin 52 (1), 1-26, 2004
4192004
Curcumin is a potent DNA hypomethylation agent
Z Liu, Z Xie, W Jones, RE Pavlovicz, S Liu, J Yu, P Li, J Lin, JR Fuchs, ...
Bioorganic & medicinal chemistry letters 19 (3), 706-709, 2009
3872009
Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia
W Blum, RB Klisovic, B Hackanson, Z Liu, S Liu, H Devine, ...
Journal of Clinical Oncology 25 (25), 3884-3891, 2007
3802007
Warfarin stereochemical aspects of its metabolism and the interaction with phenylbutazone
RJ Lewis, WF Trager, KK Chan, A Breckenridge, M Orme, M Roland, ...
The Journal of Clinical Investigation 53 (6), 1607-1617, 1974
3411974
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo
I Naasani, F Oh-Hashi, T Oh-Hara, WY Feng, J Johnston, K Chan, ...
Cancer research 63 (4), 824-830, 2003
3342003
Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia
G Marcucci, JC Byrd, G Dai, MI Klisovic, PJ Kourlas, DC Young, ...
Blood, The Journal of the American Society of Hematology 101 (2), 425-432, 2003
3162003
Sp1/NFκB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia
S Liu, LC Wu, J Pang, R Santhanam, S Schwind, YZ Wu, CJ Hickey, J Yu, ...
Cancer cell 17 (4), 333-347, 2010
2892010
Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors
MH Shah, P Binkley, K Chan, J Xiao, D Arbogast, M Collamore, Y Farra, ...
Clinical Cancer Research 12 (13), 3997-4003, 2006
2652006
Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation
A Mishra, S Liu, GH Sams, DP Curphey, R Santhanam, LJ Rush, ...
Cancer cell 22 (5), 645-655, 2012
2132012
Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia
X Huang, S Schwind, B Yu, R Santhanam, H Wang, P Hoellerbauer, ...
Clinical Cancer Research 19 (9), 2355-2367, 2013
2112013
Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice
L Zhongfa, M Chiu, J Wang, W Chen, W Yen, P Fan-Havard, LD Yee, ...
Cancer chemotherapy and pharmacology 69, 679-689, 2012
1912012
Acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in white, black, and Asian men in Los Angeles, California
MC Yu, PL Skipper, K Taghizadeh, SR Tannenbaum, KK Chan, ...
JNCI: Journal of the National Cancer Institute 86 (9), 712-716, 1994
1891994
Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics, and clinical activity
G Marcucci, W Stock, G Dai, RB Klisovic, S Liu, MI Klisovic, W Blum, ...
Journal of clinical oncology 23 (15), 3404-3411, 2005
1832005
Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive …
MI Klisovic, EA Maghraby, MR Parthun, M Guimond, AR Sklenar, ...
Leukemia 17 (2), 350-358, 2003
1812003
Arylamine exposures and bladder cancer risk
CY Mimi, PL Skipper, SR Tannenbaum, KK Chan, RK Ross
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 506, 21-28, 2002
1812002
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