Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects AM Florea, D Büsselberg Cancers 3 (1), 1351-1371, 2011 | 1866 | 2011 |
Occurrence, use and potential toxic effects of metals and metal compounds AM Florea, D Büsselberg Biometals 19, 419-427, 2006 | 441 | 2006 |
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs) R Rathore, JE McCallum, E Varghese, AM Florea, D Büsselberg Apoptosis 22 (7), 898-919, 2017 | 257 | 2017 |
Uptake of inorganic and organic derivatives of arsenic associated with induced cytotoxic and genotoxic effects in Chinese hamster ovary (CHO) cells E Dopp, LM Hartmann, AM Florea, U Von Recklinghausen, R Pieper, ... Toxicology and applied pharmacology 201 (2), 156-165, 2004 | 234 | 2004 |
Environmental distribution, analysis, and toxicity of organometal (loid) compounds E Dopp, LM Hartmann, AM Florea, AW Rettenmeier, AV Hirner Critical reviews in toxicology 34 (3), 301-333, 2004 | 200 | 2004 |
Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells C Happold, P Roth, W Wick, N Schmidt, AM Florea, M Silginer, ... Journal of neurochemistry 122 (2), 444-455, 2012 | 158 | 2012 |
Anti-cancer drugs interfere with intracellular calcium signaling AM Florea, D Büsselberg Neurotoxicology 30 (5), 803-810, 2009 | 112 | 2009 |
Forced uptake of trivalent and pentavalent methylated and inorganic arsenic and its cyto-/genotoxicity in fibroblasts and hepatoma cells E Dopp, LM Hartmann, U von Recklinghausen, AM Florea, S Rabieh, ... Toxicological Sciences 87 (1), 46-56, 2005 | 103 | 2005 |
Intracellular calcium disturbances induced by arsenic and its methylated derivatives in relation to genomic damage and apoptosis induction AM Florea, EN Yamoah, E Dopp Environmental health perspectives 113 (6), 659-664, 2005 | 103 | 2005 |
Arsenic trioxide (As2O3) induced calcium signals and cytotoxicity in two human cell lines: SY-5Y neuroblastoma and 293 embryonic kidney (HEK) AM Florea, F Splettstoesser, D Büsselberg Toxicology and Applied Pharmacology 220 (3), 292-301, 2007 | 101 | 2007 |
IP3 receptor antagonist, 2‐APB, attenuates cisplatin induced Ca2+‐influx in HeLa‐S3 cells and prevents activation of calpain and induction of apoptosis F Splettstoesser, AM Florea, D Büsselberg British journal of pharmacology 151 (8), 1176-1186, 2007 | 97 | 2007 |
Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts DM Waldera-Lupa, F Kalfalah, AM Florea, S Sass, F Kruse, V Rieder, ... Aging (Albany NY) 6 (10), 856, 2014 | 84 | 2014 |
miR-23a-3p causes cellular senescence by targeting hyaluronan synthase 2: possible implication for skin aging K Röck, J Tigges, S Sass, A Schütze, AM Florea, AC Fender, FJ Theis, ... Journal of Investigative Dermatology 135 (2), 369-377, 2015 | 80 | 2015 |
Metals and breast cancer: risk factors or healing agents? AM Florea, D Büsselberg Journal of toxicology 2011, 2011 | 68 | 2011 |
Targeting Intracellular Calcium Signaling ([Ca2+]i) to Overcome Acquired Multidrug Resistance of Cancer Cells: A Mini-Overview D Büsselberg, AM Florea Cancers 9 (5), 48, 2017 | 60 | 2017 |
MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM N Stojcheva, G Schechtmann, S Sass, P Roth, AM Florea, A Stefanski, ... Oncotarget 7 (11), 12937, 2016 | 60 | 2016 |
Thymosin beta 4 gene silencing decreases stemness and invasiveness in glioblastoma HG Wirsching, S Krishnan, AM Florea, K Frei, N Krayenbühl, ... Brain 137 (2), 433-448, 2014 | 53 | 2014 |
Co-application of arsenic trioxide (As2O3) and cisplatin (CDDP) on human SY-5Y neuroblastoma cells has differential effects on the intracellular calcium concentration ([Ca2+] i … DA Günes, AM Florea, F Splettstoesser, D Büsselberg Neurotoxicology 30 (2), 194-202, 2009 | 53 | 2009 |
Interferon-β induces loss of spherogenicity and overcomes therapy resistance of glioblastoma stem cells C Happold, P Roth, M Silginer, AM Florea, K Lamszus, K Frei, R Deenen, ... Molecular cancer therapeutics 13 (4), 948-961, 2014 | 52 | 2014 |
Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca2+] i) homeostasis N Al-Taweel, E Varghese, AM Florea, D Büsselberg The Journal of Toxicological Sciences 39 (5), 765-774, 2014 | 51 | 2014 |