| Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair J Lafrance-Vanasse, GJ Williams, JA Tainer Progress in biophysics and molecular biology 117 (2-3), 182-193, 2015 | 134 | 2015 |
| The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once SE Tsutakawa, J Lafrance-Vanasse, JA Tainer DNA repair 19, 95-107, 2014 | 110 | 2014 |
| Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development A L'Honoré, V Coulon, A Marcil, M Lebel, J Lafrance-Vanasse, P Gage, ... Developmental biology 307 (2), 421-433, 2007 | 96 | 2007 |
| High resolution reaction intermediates of rabbit muscle fructose-1, 6-bisphosphate aldolase: substrate cleavage and induced fit M St-Jean, J Lafrance-Vanasse, B Liotard, J Sygusch Journal of Biological Chemistry 280 (29), 27262-27270, 2005 | 78 | 2005 |
| Crystal structures of the organomercurial lyase MerB in its free and mercury-bound forms: insights into the mechanism of methylmercury degradation J Lafrance-Vanasse, M Lefebvre, P Di Lello, J Sygusch, JG Omichinski Journal of Biological Chemistry 284 (2), 938-944, 2009 | 74 | 2009 |
| Structural and functional characterization of an atypical activation domain in erythroid Krüppel-like factor (EKLF) C Mas, M Lussier-Price, S Soni, T Morse, G Arseneault, P Di Lello, ... Proceedings of the National Academy of Sciences 108 (26), 10484-10489, 2011 | 64 | 2011 |
| Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease G Ayalon, SH Lee, O Adolfsson, C Foo-Atkins, JK Atwal, M Blendstrup, ... Science Translational Medicine 13 (593), eabb2639, 2021 | 58 | 2021 |
| The Rad50 hook domain regulates DNA damage signaling and tumorigenesis R Roset, A Inagaki, M Hohl, F Brenet, J Lafrance-Vanasse, J Lange, ... Genes & development 28 (5), 451-462, 2014 | 57 | 2014 |
| Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu (I) center to initiate O2 activation MJ Appel, KK Meier, J Lafrance-Vanasse, H Lim, CL Tsai, B Hedman, ... Proceedings of the National Academy of Sciences 116 (12), 5370-5375, 2019 | 47 | 2019 |
| Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression HH Chen, P Liu, P Auger, SH Lee, O Adolfsson, L Rey-Bellet, ... Scientific reports 8 (1), 16725, 2018 | 47 | 2018 |
| An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans S Chung, V Nguyen, YL Lin, J Lafrance-Vanasse, SJ Scales, K Lin, ... MAbs 11 (5), 942-955, 2019 | 46 | 2019 |
| Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER J Lafrance-Vanasse, G Arseneault, L Cappadocia, P Legault, ... Nucleic acids research 41 (4), 2736-2745, 2013 | 43 | 2013 |
| Structural and functional characterization of interactions involving the Tfb1 subunit of TFIIH and the NER factor Rad2 J Lafrance-Vanasse, G Arseneault, L Cappadocia, HT Chen, P Legault, ... Nucleic acids research 40 (12), 5739-5750, 2012 | 31 | 2012 |
| Development, optimization, and structural characterization of an efficient peptide-based photoaffinity cross-linking reaction for generation of homogeneous conjugates from wild … N Vance, N Zacharias, M Ultsch, G Li, A Fourie, P Liu, ... Bioconjugate Chemistry 30 (1), 148-160, 2018 | 24 | 2018 |
| Structural and biochemical characterization of a copper-binding mutant of the Organomercurial Lyase MerB: insight into the key role of the active site aspartic acid in Hg … HM Wahba, L Lecoq, M Stevenson, A Mansour, L Cappadocia, ... Biochemistry 55 (7), 1070-1081, 2016 | 22 | 2016 |
| Translational approaches for brain delivery of biologics via cerebrospinal fluid SS Sadekar, M Bowen, H Cai, S Jamalian, H Rafidi, W Shatz‐Binder, ... Clinical Pharmacology & Therapeutics 111 (4), 826-834, 2022 | 19 | 2022 |
| Structure-based design of a potent artificial transactivation domain based on p53 C Langlois, A Del Gatto, G Arseneault, J Lafrance-Vanasse, M De Simone, ... Journal of the American Chemical Society 134 (3), 1715-1723, 2012 | 12 | 2012 |
| Carboxy-Terminus Recruitment Induced by Substrate Binding in Eukaryotic Fructose Bis-phosphate Aldolases, J Lafrance-Vanasse, J Sygusch Biochemistry 46 (33), 9533-9540, 2007 | 12 | 2007 |
| Structural characterization of a noncovalent complex between ubiquitin and the transactivation domain of the erythroid-specific factor EKLF L Raiola, M Lussier-Price, D Gagnon, J Lafrance-Vanasse, X Mascle, ... Structure 21 (11), 2014-2024, 2013 | 9 | 2013 |
| The Organomercurial lyase Mer B PD Lello, J Lafrance‐Vanasse, JG Omichinski Handbook of metalloproteins, 2006 | 6 | 2006 |
