Abhishek Bharadwaj Sharma

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Sherif El-KhamisyDirector of Research and InnovationVerified email at sheffield.ac.uk
Helen BlairNewcastle UniversityVerified email at ncl.ac.uk
Danny HuylebroeckErasmus University Medical Center and KULeuvenVerified email at erasmusmc.nl
Junko MuraiAssociate Professor, Ehime UniversityVerified email at ehime-u.ac.jp
Yves PommierChief, Developmental Therapeutics Branch & Laboratory of Molecular PharmacologyVerified email at nih.gov
Shih-Chieh ChiangPostdoctoral researcher, University of SheffieldVerified email at sheffield.ac.uk
Meryem AlagozSussex UniversityVerified email at sussex.ac.uk
Ali HamicheCNRSVerified email at igbmc.fr
BrittonIPBS CNRSVerified email at ipbs.fr
Josef VormoorSir James Spence Professor of Child Health, Newcastle UniversityVerified email at ncl.ac.uk
Chris M BaconSenior Lecturer in Haematopathology, Newcastle UniveristyVerified email at ncl.ac.uk
Nicola CurtinNewcastle UniversityVerified email at ncl.ac.uk
Jean-Yves MassonCHU de Québec-Université LavalVerified email at crchudequebec.ulaval.ca
Sabrina FRITAHLuxembourg Institute of HealthVerified email at lih.lu
Simone P. NiclouUniversity of LuxembourgVerified email at lih.lu
Petr V. NazarovLuxembourg Institute of HealthVerified email at lih.lu
Philippe PaseroInstitute of Human Genetics, Montpellier, FranceVerified email at igh.cnrs.fr
Thibaut PeterliniPhD, Chercheur en microbiologie appliquée et gestion intégrée de zones côtières, ValorēsVerified email at ulaval.ca
Michael L. NielsenNovo Nordisk Foundation Center for Protein ResearchVerified email at cpr.ku.dk
Sara C. Buch-LarsenNovo Nordisk Foundation, Center for Protein Research, University of CopenhagenVerified email at cpr.ku.dk

Abhishek Bharadwaj Sharma

University of Oxford

Verified email at bioch.ox.ac.uk - Homepage

DNA maintenance Cell cycle and Cancer DNA repair


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TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1 Z Zeng, AB Sharma, L Ju, J Murai, L Umans, L Vermeire, Y Pommier, ... Nucleic acids research 40 (17), 8371-8380, 2012	107	2012
ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells M Alagoz, SC Chiang, AB Sharma, SF El-Khamisy PloS one 8 (4), e58239, 2013	76	2013
Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks AB Sharma, S Dimitrov, A Hamiche, E Van Dyck Nucleic acids research 47 (3), 1051-1069, 2019	61	2019
Development of a preclinical orthotopic xenograft model of ewing sarcoma and other human malignant bone disease using advanced in vivo imaging B Vormoor, HK Knizia, MA Batey, GS Almeida, I Wilson, P Dildey, ... PloS one 9 (1), e85128, 2014	42	2014
Sensitizing Ewing sarcoma to chemo-and radiotherapy by inhibition of the DNA-repair enzymes DNA protein kinase (DNA-PK) and poly-ADP-ribose polymerase (PARP) 1/2 B Vormoor, YT Schlosser, H Blair, AB Sharma, S Wilkinson, DR Newell, ... Oncotarget 8 (69), 113418, 2017	30	2017
XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase AB Sharma, H Erasimus, L Pinto, MC Caron, D Gopaul, T Peterlini, ... Nucleic acids research 49 (17), 9906-9925, 2021	11	2021
Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3 F Richards, MJ Llorca-Cardenosa, J Langton, SC Buch-Larsen, ... Nature Communications 14 (1), 4310, 2023	3	2023
Abstract P22: C16orf72/HAPSTR1/TAPR1 Interacts with BRCA1 and Senataxin to Regulate R-loops at Stalled Replication Forks and Confer Resistance to PARP Disruption AB Sharma, MK Ramlee, J Kosmin, MR Higgs, A Wolstenholme, ... Cancer Research 84 (8_Supplement), P22-P22, 2024		2024
DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks LM Pinto, A Pailas, M Bondarchenko, AB Sharma, K Neumann, AJ Rizzo, ... Nucleic Acids Research 52 (3), 1136-1155, 2024		2024
C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption AB Sharma, MK Ramlee, J Kosmin, A Wolstenholme, G Ronson, D Jones, ... Nature Communications 14, 2023		2023
XAB2 prevents abortive recombinational repair of replication-associated DNA double-strand breaks and its loss is synthetic lethal with RAD52 inhibition AB Sharma, H Erasimus, L Pinto, MC Caron, K Neumann, PV Nazarov, ... bioRxiv, 2020.04. 10.035410, 2020		2020
Role of CHRAC14 and histone methyltransferase Su (var) 3-9 in facilitating ectopic loading of CENP-A AB Sharma Central for Molecular Biology Heidelberg (ZMBH), Heidelberg University, 2017		2017

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