| Genetic CD21 deficiency is associated with hypogammaglobulinemia J Thiel, L Kimmig, U Salzer, M Grudzien, D Lebrecht, T Hagena, ... Journal of allergy and clinical immunology 129 (3), 801-810. e6, 2012 | 226 | 2012 |
| USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis A Aichem, C Pelzer, S Lukasiak, B Kalveram, PW Sheppard, N Rani, ... Nature communications 1 (1), 13, 2010 | 101 | 2010 |
| FAT10ylation as a signal for proteasomal degradation G Schmidtke, A Aichem, M Groettrup Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (1), 97-102, 2014 | 99 | 2014 |
| The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation A Aichem, B Kalveram, V Spinnenhirn, K Kluge, N Catone, T Johansen, ... Journal of cell science 125 (19), 4576-4585, 2012 | 94 | 2012 |
| FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis N Rani, A Aichem, G Schmidtke, SG Kreft, M Groettrup Nature communications 3 (1), 749, 2012 | 81 | 2012 |
| The ubiquitin-like modifier FAT10 in cancer development A Aichem, M Groettrup The international journal of biochemistry & cell biology 79, 451-461, 2016 | 76 | 2016 |
| The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice V Spinnenhirn, H Farhan, M Basler, A Aichem, A Canaan, M Groettrup Journal of cell science 127 (22), 4883-4893, 2014 | 64 | 2014 |
| The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells A Dufner, A Kisser, S Niendorf, A Basters, S Reissig, A Schönle, A Aichem, ... Nature immunology 16 (9), 950-960, 2015 | 55 | 2015 |
| Ca2+/calmodulin-independent activation of calcineurin from Dictyostelium by unsaturated long chain fatty acids U Kessen, R Schaloske, A Aichem, R Mutzel Journal of Biological Chemistry 274 (53), 37821-37826, 1999 | 45 | 1999 |
| The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation A Aichem, S Anders, N Catone, P Rößler, S Stotz, A Berg, R Schwab, ... Nature communications 9 (1), 3321, 2018 | 38 | 2018 |
| Investigations into the auto‐FAT 10ylation of the bispecific E 2 conjugating enzyme UB A6‐specific E 2 enzyme 1 A Aichem, N Catone, M Groettrup The FEBS journal 281 (7), 1848-1859, 2014 | 37 | 2014 |
| Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation J Bialas, M Groettrup, A Aichem PloS one 10 (3), e0120329, 2015 | 34 | 2015 |
| The ubiquitin-like modifier FAT10 interferes with SUMO activation A Aichem, C Sailer, S Ryu, N Catone, N Stankovic-Valentin, G Schmidtke, ... Nature communications 10 (1), 4452, 2019 | 32 | 2019 |
| Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy ND Roverato, C Sailer, N Catone, A Aichem, F Stengel, M Groettrup Cell reports 34 (11), 2021 | 27 | 2021 |
| Redox regulation of CD21 shedding involves signaling via PKC and indicates the formation of a juxtamembrane stalk A Aichem, M Masilamani, H Illges Journal of cell science 119 (14), 2892-2902, 2006 | 27 | 2006 |
| The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6 A Sacristan-Reviriego, J Bellingham, C Prodromou, AN Boehm, A Aichem, ... Human molecular genetics 26 (22), 4465-4480, 2017 | 26 | 2017 |
| The ubiquitin-like modifier FAT10–much more than a proteasome-targeting signal A Aichem, M Groettrup Journal of cell science 133 (14), jcs246041, 2020 | 25 | 2020 |
| The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1 J Bialas, AN Boehm, N Catone, A Aichem, M Groettrup Journal of Biological Chemistry 294 (12), 4315-4330, 2019 | 24 | 2019 |
| Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum: the role of cAMP receptor subtypes and G protein subunits J Sonnemann, A Aichem, C Schlatterer FEBS letters 436 (2), 271-276, 1998 | 19 | 1998 |
| Newly translated proteins are substrates for ubiquitin, ISG15, and FAT10 V Spinnenhirn, A Bitzer, A Aichem, M Groettrup FEBS letters 591 (1), 186-195, 2017 | 15 | 2017 |
