Chemically defined antibody–and small molecule–drug conjugates for in vivo tumor targeting applications: a comparative analysis S Cazzamalli, A Dal Corso, F Widmayer, D Neri Journal of the American Chemical Society 140 (5), 1617-1621, 2018 | 132 | 2018 |
Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold Y Li, R De Luca, S Cazzamalli, F Pretto, D Bajic, J Scheuermann, D Neri Nature chemistry 10 (4), 441-448, 2018 | 116 | 2018 |
Protease-cleavable linkers modulate the anticancer activity of noninternalizing antibody–drug conjugates A Dal Corso, S Cazzamalli, R Gébleux, M Mattarella, D Neri Bioconjugate chemistry 28 (7), 1826-1833, 2017 | 85 | 2017 |
Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma S Cazzamalli, A Dal Corso, D Neri Journal of Controlled Release 246, 39-45, 2017 | 76 | 2017 |
Enhanced therapeutic activity of non-internalizing small-molecule-drug conjugates targeting carbonic anhydrase IX in combination with targeted interleukin-2 S Cazzamalli, B Ziffels, F Widmayer, P Murer, G Pellegrini, F Pretto, ... Clinical Cancer Research 24 (15), 3656-3667, 2018 | 68 | 2018 |
Acetazolamide serves as selective delivery vehicle for dipeptide-linked drugs to renal cell carcinoma S Cazzamalli, A Dal Corso, D Neri Molecular cancer therapeutics 15 (12), 2926-2935, 2016 | 61 | 2016 |
An ultra-high-affinity small organic ligand of fibroblast activation protein for tumor-targeting applications J Millul, G Bassi, J Mock, A Elsayed, C Pellegrino, A Zana, S Dakhel Plaza, ... Proceedings of the National Academy of Sciences 118 (16), e2101852118, 2021 | 59 | 2021 |
An efficient continuous flow process for the synthesis of a non-conventional mixture of fructooligosaccharides P Zambelli, L Tamborini, S Cazzamalli, A Pinto, S Arioli, S Balzaretti, ... Food Chemistry 190, 607-613, 2016 | 52 | 2016 |
The antibody‐based delivery of interleukin‐12 to solid tumors boosts NK and CD8+ T cell activity and synergizes with immune checkpoint inhibitors E Puca, P Probst, M Stringhini, P Murer, G Pellegrini, S Cazzamalli, ... International journal of cancer 146 (9), 2518-2530, 2020 | 46 | 2020 |
Stereo-and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications N Favalli, G Bassi, C Pellegrino, J Millul, R De Luca, S Cazzamalli, ... Nature chemistry 13 (6), 540-548, 2021 | 39 | 2021 |
Translational imaging of the fibroblast activation protein (FAP) using the new ligand [68Ga]Ga-OncoFAP-DOTAGA P Backhaus, F Gierse, MC Burg, F Büther, I Asmus, P Dorten, J Cufe, ... European Journal of Nuclear Medicine and Molecular Imaging, 1-11, 2022 | 34 | 2022 |
Impact of a central scaffold on the binding affinity of fragment pairs isolated from DNA‐encoded self‐assembling chemical libraries M Bigatti, A Dal Corso, S Vanetti, S Cazzamalli, U Rieder, J Scheuermann, ... ChemMedChem 12 (21), 1748-1752, 2017 | 30 | 2017 |
In vivo antitumor activity of a novel acetazolamide–cryptophycin conjugate for the treatment of renal cell carcinomas S Cazzamalli, E Figueras, L Pethő, A Borbély, C Steinkühler, D Neri, ... ACS omega 3 (11), 14726-14731, 2018 | 29 | 2018 |
A microdosing study with 99mTc-PHC-102 for the SPECT/CT imaging of primary and metastatic lesions in renal cell carcinoma patients OC Kulterer, S Pfaff, W Wadsak, N Garstka, M Remzi, C Vraka, L Nics, ... Journal of Nuclear Medicine 62 (3), 360-365, 2021 | 26 | 2021 |
A novel anti-cancer L19-interleukin-12 fusion protein with an optimized peptide linker efficiently localizes in vivo at the site of tumors T Ongaro, M Matasci, S Cazzamalli, B Gouyou, R De Luca, D Neri, A Villa Journal of biotechnology 291, 17-25, 2019 | 26 | 2019 |
Targeted delivery of cytotoxic drugs: Challenges, opportunities and new developments S Cazzamalli, A Dal Corso, D Neri Chimia 71 (10), 712, 2017 | 20 | 2017 |
A dimeric FAP-targeting small-molecule radioconjugate with high and prolonged tumor uptake A Galbiati, A Zana, M Bocci, J Millul, A Elsayed, J Mock, D Neri, ... Journal of Nuclear Medicine 63 (12), 1852-1858, 2022 | 19 | 2022 |
Impact of ligand size and conjugation chemistry on the performance of universal chimeric antigen receptor T-cells for tumor killing C Pellegrino, N Favalli, M Sandholzer, L Volta, G Bassi, J Millul, ... Bioconjugate chemistry 31 (7), 1775-1783, 2020 | 18 | 2020 |
Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics L Lucaroni, T Georgiev, E Prodi, S Puglioli, C Pellegrino, N Favalli, L Prati, ... European Journal of Nuclear Medicine and Molecular Imaging 50 (3), 957-961, 2023 | 17 | 2023 |
Immunotherapy with immunocytokines and PD-1 blockade enhances the anticancer activity of small molecule-drug conjugates targeting carbonic anhydrase IX J Millul, C Krudewig, A Zana, S Dakhel Plaza, E Puca, A Villa, D Neri, ... Molecular Cancer Therapeutics 20 (3), 512-522, 2021 | 11 | 2021 |