Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics JY Li, B Chassaing, AM Tyagi, C Vaccaro, T Luo, J Adams, TM Darby, ... The Journal of clinical investigation 126 (6), 2049-2063, 2016 | 520 | 2016 |
The microbial metabolite butyrate stimulates bone formation via T regulatory cell-mediated regulation of WNT10B expression AM Tyagi, M Yu, TM Darby, C Vaccaro, JY Li, JA Owens, E Hsu, J Adams, ... Immunity 49 (6), 1116-1131. e7, 2018 | 335 | 2018 |
Lactobacilli modulate epithelial cytoprotection through the Nrf2 pathway RM Jones, C Desai, TM Darby, L Luo, AA Wolfarth, CD Scharer, CS Ardita, ... Cell reports 12 (8), 1217-1225, 2015 | 201 | 2015 |
Gut-resident lactobacilli activate hepatic Nrf2 and protect against oxidative liver injury BJ Saeedi, KH Liu, JA Owens, S Hunter-Chang, MC Camacho, RU Eboka, ... Cell metabolism 31 (5), 956-968. e5, 2020 | 176 | 2020 |
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis S Yang, B Wang, F Humphries, R Jackson, ME Healy, R Bergin, G Aviello, ... Nature immunology 14 (9), 927-936, 2013 | 110 | 2013 |
Characterization of pro-inflammatory flagellin proteins produced by Lactobacillus ruminis and related motile lactobacilli BA Neville, BM Forde, MJ Claesson, T Darby, A Coghlan, K Nally, ... PLoS One 7 (7), e40592, 2012 | 95 | 2012 |
Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk MR Kudelka, BH Hinrichs, T Darby, CS Moreno, H Nishio, CE Cutler, ... Proceedings of the National Academy of Sciences 113 (51), 14787-14792, 2016 | 81 | 2016 |
Differential expression of key regulators of Toll-like receptors in ulcerative colitis and Crohn's disease: a role for Tollip and peroxisome proliferator-activated receptor gamma? P Fernandes, J MacSharry, T Darby, A Fanning, F Shanahan, A Houston, ... Clinical & Experimental Immunology 183 (3), 358-368, 2016 | 78 | 2016 |
The complex role of inflammasomes in the pathogenesis of inflammatory bowel diseases–lessons learned from experimental models M Aguilera, T Darby, S Melgar Cytokine & growth factor reviews 25 (6), 715-730, 2014 | 73 | 2014 |
Lactococcus lactis subspecies cremoris elicits protection against metabolic changes induced by a western-style diet CR Naudin, K Maner-Smith, JA Owens, GM Wynn, BS Robinson, ... Gastroenterology 159 (2), 639-651. e5, 2020 | 63 | 2020 |
Lactobacillus rhamnosus GG orchestrates an antitumor immune response JA Owens, BJ Saeedi, CR Naudin, S Hunter-Chang, ME Barbian, ... Cellular and Molecular Gastroenterology and Hepatology 12 (4), 1311-1327, 2021 | 52 | 2021 |
A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes HP McLaughlin, Q Xiao, RB Rea, H Pi, PG Casey, T Darby, A Charbit, ... PloS one 7 (2), e30928, 2012 | 41 | 2012 |
Lactococcus Lactis Subsp. cremoris is an efficacious beneficial bacterium that limits tissue injury in the intestine TM Darby, JA Owens, BJ Saeedi, L Luo, JD Matthews, BS Robinson, ... Iscience 12, 356-367, 2019 | 40 | 2019 |
Microbial metabolite delta-valerobetaine is a diet-dependent obesogen KH Liu, JA Owens, B Saeedi, CE Cohen, MP Bellissimo, C Naudin, ... Nature metabolism 3 (12), 1694-1705, 2021 | 36 | 2021 |
The gut microbiota is a transmissible determinant of skeletal maturation AM Tyagi, TM Darby, E Hsu, M Yu, S Pal, H Dar, JY Li, J Adams, ... Elife 10, e64237, 2021 | 29 | 2021 |
Bifidobacterium adolescentis supplementation attenuates fracture-induced systemic sequelae JL Roberts, G Liu, TM Darby, LM Fernandes, ME Diaz-Hernandez, ... Biomedicine & Pharmacotherapy 132, 110831, 2020 | 29 | 2020 |
Lactobacillus rhamnosus GG–induced expression of leptin in the intestine orchestrates epithelial cell proliferation TM Darby, CR Naudin, L Luo, RM Jones Cellular and molecular gastroenterology and hepatology 9 (4), 627-639, 2020 | 28 | 2020 |
Proteomic analysis of microbial induced redox-dependent intestinal signaling JD Matthews, AR Reedy, H Wu, BH Hinrichs, TM Darby, C Addis, ... Redox Biology 20, 526-532, 2019 | 22 | 2019 |
Beneficial influences of Lactobacillus plantarum on human health and disease TM Darby, RM Jones The microbiota in gastrointestinal pathophysiology, 109-117, 2017 | 20 | 2017 |
Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50 M Canavan, C McCarthy, NB Larbi, JK Dowling, L Collins, F O’Sullivan, ... Innate immunity 20 (7), 675-687, 2014 | 18 | 2014 |