| Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia N Chen, Y Cai, Q Chen, R Li, K Wang, Y Huang, S Hu, S Huang, H Zhang, ... Nature Communications 9 (1), 2337, 2018 | 279 | 2018 |
| Correction of the Marfan syndrome pathogenic FBN1 mutation by base editing in human cells and heterozygous embryos Y Zeng, J Li, G Li, S Huang, W Yu, Y Zhang, D Chen, J Chen, J Liu, ... Molecular therapy 26 (11), 2631-2637, 2018 | 158 | 2018 |
| Efficient generation of mouse models of human diseases via ABE-and BE-mediated base editing Z Liu, Z Lu, G Yang, S Huang, G Li, S Feng, Y Liu, J Li, W Yu, Y Zhang, ... Nature communications 9 (1), 2338, 2018 | 151 | 2018 |
| BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity W Jiang, S Feng, S Huang, W Yu, G Li, G Yang, Y Liu, Y Zhang, L Zhang, ... Cell Research 28 (8), 855-861, 2018 | 142 | 2018 |
| The origin of domestication genes in goats Z Zheng, X Wang, M Li, Y Li, Z Yang, X Wang, X Pan, M Gong, Y Zhang, ... Science Advances 6 (21), eaaz5216, 2020 | 112 | 2020 |
| Enhancement of prime editing via xrRNA motif-joined pegRNA G Zhang, Y Liu, S Huang, S Qu, D Cheng, Y Yao, Q Ji, X Wang, X Huang, ... Nature communications 13 (1), 1856, 2022 | 62 | 2022 |
| Efficient gene silencing by adenine base editor-mediated start codon mutation X Wang, Z Liu, GL Li, L Dang, S Huang, L He, C Li, M Liu, G Yang, ... Molecular Therapy 28 (2), 431-440, 2020 | 53 | 2020 |
| A Cas-embedding strategy for minimizing off-target effects of DNA base editors Y Liu, C Zhou, S Huang, L Dang, Y Wei, J He, Y Zhou, S Mao, W Tao, ... Nature communications 11 (1), 6073, 2020 | 51 | 2020 |
| Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity J Li, W Yu, S Huang, S Wu, L Li, J Zhou, Y Cao, X Huang, Y Qiao Nature Communications 12 (1), 2287, 2021 | 48 | 2021 |
| Highly efficient and precise base editing by engineered dCas9-guide tRNA adenosine deaminase in rats Y Ma, L Yu, X Zhang, C Xin, S Huang, L Bai, W Chen, R Gao, J Li, S Pan, ... Cell Discovery 4 (1), 39, 2018 | 47 | 2018 |
| Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice Z Lu, Z Liu, W Mao, X Wang, X Zheng, S Chen, B Cao, S Huang, X Zhang, ... Cell Death & Disease 11 (2), 85, 2020 | 36 | 2020 |
| Enhancing prime editing efficiency by modified pegRNA with RNA G-quadruplexes X Li, X Wang, W Sun, S Huang, M Zhong, Y Yao, Q Ji, X Huang Journal of molecular cell biology 14 (4), mjac022, 2022 | 35 | 2022 |
| Base-editing-mediated R17H substitution in histone H3 reveals methylation-dependent regulation of Yap signaling and early mouse embryo development G Yang, C Zhou, R Wang, S Huang, Y Wei, X Yang, Y Liu, J Li, Z Lu, ... Cell Reports 26 (2), 302-312. e4, 2019 | 30 | 2019 |
| Developing ABEmax-NG with precise targeting and expanded editing scope to model pathogenic splice site mutations in vivo S Huang, Z Liao, X Li, Z Liu, G Li, J Li, Z Lu, Y Zhang, X Li, X Ma, Q Sun, ... Iscience 15, 640-648, 2019 | 26 | 2019 |
| REPAIR x, a specific yet highly efficient programmable A> I RNA base editor Y Liu, S Mao, S Huang, Y Li, Y Chen, M Di, X Huang, J Lv, X Wang, J Ge, ... The EMBO Journal 39 (22), e104748, 2020 | 23 | 2020 |
| High-resolution annotation of the mouse preimplantation embryo transcriptome using long-read sequencing Y Qiao, C Ren, S Huang, J Yuan, X Liu, J Fan, J Lin, S Wu, Q Chen, X Bo, ... Nature Communications 11 (1), 2653, 2020 | 23 | 2020 |
| Modeling a cataract disorder in mice with prime editing J Lin, X Liu, Z Lu, S Huang, S Wu, W Yu, Y Liu, X Zheng, X Huang, Q Sun, ... Molecular Therapy-Nucleic Acids 25, 494-501, 2021 | 21 | 2021 |
| Efficient generation of pathogenic A-to-G mutations in human tripronuclear embryos via ABE-mediated base editing G Li, X Liu, S Huang, Y Zeng, G Yang, Z Lu, Y Zhang, X Ma, L Wang, ... Molecular Therapy-Nucleic Acids 17, 289-296, 2019 | 19 | 2019 |
| PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction M Zhong, K Chen, W Sun, X Li, S Huang, Q Meng, B Sun, X Huang, ... Biosensors and Bioelectronics 214, 114497, 2022 | 18 | 2022 |
| Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome J Li, Z Liu, S Huang, X Wang, G Li, Y Xu, W Yu, S Chen, Y Zhang, H Ma, ... Cell Research 29 (2), 174-176, 2019 | 17 | 2019 |
