PRC2 mediated H3K27 methylations in cellular identity and cancer E Conway, E Healy, AP Bracken Current opinion in cell biology 37, 42-48, 2015 | 220 | 2015 |
PRC2. 1 and PRC2. 2 synergize to coordinate H3K27 trimethylation E Healy, M Mucha, E Glancy, DJ Fitzpatrick, E Conway, HK Neikes, ... Molecular cell 76 (3), 437-452. e6, 2019 | 156 | 2019 |
A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018 | 133 | 2018 |
MutSβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells AMM Gannon, A Frizzell, E Healy, RS Lahue Nucleic acids research 40 (20), 10324-10333, 2012 | 68 | 2012 |
A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence GL Brien, E Healy, E Jerman, E Conway, E Fadda, D O'Donovan, ... Genes & development 29 (21), 2231-2243, 2015 | 41 | 2015 |
Simultaneous disruption of PRC2 and enhancer function underlies histone H3. 3-K27M oncogenic activity in human hindbrain neural stem cells GL Brien, RB Bressan, C Monger, D Gannon, E Lagan, AM Doherty, ... Nature Genetics 53 (8), 1221-1232, 2021 | 38 | 2021 |
PRC2. 1-and PRC2. 2-specific accessory proteins drive recruitment of different forms of canonical PRC1 E Glancy, C Wang, E Tuck, E Healy, S Amato, HK Neikes, A Mariani, ... Molecular cell 83 (9), 1393-1411. e7, 2023 | 14 | 2023 |
The apparent loss of PRC2 chromatin occupancy as an artifact of RNA depletion E Healy, Q Zhang, EH Gail, SC Agius, G Sun, M Bullen, V Pandey, ... Cell Reports 43 (3), 2024 | 7 | 2024 |
If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of VPRC1 and CPRC1 E Healy, AP Bracken Molecular Cell 77 (4), 685-687, 2020 | 4 | 2020 |
EZH1-PRC2 Identifies a Potential Reservoir for Disease Relapse in Quiescent Cancer Cells Refractory to EZH2 Enzymatic Inhibition E Healy, R McCole, C Monger, J Nolan, E Conway, G Brien, C Wang, ... Blood 140 (Supplement 1), 3049-3050, 2022 | | 2022 |
Understanding the Diverse Roles of Polycomb-like Proteins in the Regulation of Chromatin and Transcriptional Landscapes E Healy Trinity College Dublin, 2019 | | 2019 |
Canonical PRC1 Recruitment Is Promoted by EZH1-PRC2 Independent of H3K27me3 in Quiescent Cells E Healy, R McCole, C Monger, G Brien, C Wang, HK Neikes, F Potjewyd, ... Available at SSRN 4089979, 0 | | |