| Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis M Cinar, FS Hamedani, Z Mo, B Cinar, HM Amin, S Alkan Leukemia Research 37 (10), 1271-1277, 2013 | 163 | 2013 |
| Cholesterol sensitivity of endogenous and myristoylated Akt RM Adam, NK Mukhopadhyay, J Kim, D Di Vizio, B Cinar, K Boucher, ... Cancer Research 67 (13), 6238-6246, 2007 | 155 | 2007 |
| The pro‐apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1 B Cinar, PK Fang, M Lutchman, D Di Vizio, RM Adam, N Pavlova, ... The EMBO Journal 26 (21), 4523-4534, 2007 | 151 | 2007 |
| Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer MR Freeman, B Cinar, ML Lu Trends in Endocrinology & Metabolism 16 (6), 273-279, 2005 | 116 | 2005 |
| YAP1 and AR interactions contribute to the switch from androgen-dependent to castration-resistant growth in prostate cancer G Kuser-Abali, A Alptekin, M Lewis, IP Garraway, B Cinar Nature communications 6 (1), 8126, 2015 | 105 | 2015 |
| Phosphoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdomains B Cinar, NK Mukhopadhyay, G Meng, MR Freeman Journal of Biological Chemistry 282 (40), 29584-29593, 2007 | 104 | 2007 |
| Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells HS Soifer, N Souleimanian, S Wu, AM Voskresenskiy, FK Collak, B Cinar, ... Journal of Biological Chemistry 287 (6), 3777-3787, 2012 | 98 | 2012 |
| Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin B Cinar, A De Benedetti, MR Freeman Cancer Research 65 (7), 2547-2553, 2005 | 80 | 2005 |
| Androgen receptor mediates the reduced tumor growth, enhanced androgen responsiveness, and selected target gene transactivation in a human prostate cancer cell line B Cinar, KS Koeneman, M Edlund, GS Prins, HE Zhau, LWK Chung Cancer Research 61 (19), 7310-7317, 2001 | 78 | 2001 |
| Transit of hormonal and EGF receptor-dependent signals through cholesterol-rich membranes MR Freeman, B Cinar, J Kim, NK Mukhopadhyay, D Di Vizio, RM Adam, ... Steroids 72 (2), 210-217, 2007 | 74 | 2007 |
| The zinc finger protein ras-responsive element binding protein-1 is a coregulator of the androgen receptor: implications for the role of the Ras pathway in enhancing androgenic … NK Mukhopadhyay, B Cinar, L Mukhopadhyay, M Lutchman, ... Molecular Endocrinology 21 (9), 2056-2070, 2007 | 66 | 2007 |
| Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation NK Mukhopadhyay, J Kim, B Cinar, A Ramachandran, MH Hager, ... Cancer Research 69 (6), 2210-2218, 2009 | 65 | 2009 |
| Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile … FK Collak, K Yagiz, DJ Luthringer, B Erkaya, B Cinar Journal of Biological Chemistry 287 (28), 23698-23709, 2012 | 61 | 2012 |
| Identification of a negative regulatory cis-element in the enhancer core region of the prostate-specific antigen promoter: implications for intersection of androgen receptor … B Cinar, F Yeung, H Konaka, MW Mayo, MR Freeman, HE Zhau, ... Biochemical Journal 379 (2), 421-431, 2004 | 51 | 2004 |
| STAT3 and STAT5A are potential therapeutic targets in castration-resistant prostate cancer SK Mohanty, K Yagiz, D Pradhan, DJ Luthringer, MB Amin, S Alkan, ... Oncotarget 8 (49), 85997, 2017 | 48 | 2017 |
| Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor NK Mukhopadhyay, AS Ferdinand, L Mukhopadhyay, B Cinar, ... Experimental Cell Research 312 (19), 3782-3795, 2006 | 47 | 2006 |
| Identification and characterization of estrogen receptor variants in prostate cancer cell lines Q Ye, LWK Chung, B Cinar, S Li, HE Zhau The Journal of Steroid Biochemistry and Molecular Biology 75 (1), 21-31, 2000 | 46 | 2000 |
| MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling B Cinar, FK Collak, D Lopez, S Akgul, NK Mukhopadhyay, M Kilicarslan, ... Cancer Research 71 (12), 4303-4313, 2011 | 42 | 2011 |
| Overexpression of MYC and EZH2 cooperates to epigenetically silence MST1 expression. G Kuser-Abali, A Alptekin, B Cinar Epigenetics 9 (4), 634 - 643, 2014 | 41 | 2014 |
| Concurrent inhibition of MYC and BCL2 is a potentially effective treatment strategy for double hit and triple hit B-cell lymphomas M Cinar, F Rosenfelt, S Rokhsar, J Lopategui, R Pillai, M Cervania, A Pao, ... Leukemia research 39 (7), 730-738, 2015 | 35 | 2015 |
Michael R. FreemanProfessor, Cancer Biology, Cedars-Sinai Medical CenterVerified email at cshs.org
