| Microenvironmental regulation of tumor progression and metastasis DF Quail, JA Joyce Nature medicine 19 (11), 1423-1437, 2013 | 7405 | 2013 |
| Microenvironmental regulation of metastasis JA Joyce, JW Pollard Nature reviews cancer 9 (4), 239-252, 2009 | 4382 | 2009 |
| CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2208 | 2013 |
| T cell exclusion, immune privilege, and the tumor microenvironment JA Joyce, DT Fearon Science 348 (6230), 74-80, 2015 | 2099 | 2015 |
| The microenvironmental landscape of brain tumors DF Quail, JA Joyce Cancer cell 31 (3), 326-341, 2017 | 1382 | 2017 |
| IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion V Gocheva, HW Wang, BB Gadea, T Shree, KE Hunter, AL Garfall, ... Genes & development 24 (3), 241-255, 2010 | 874 | 2010 |
| Therapeutic targeting of the tumor microenvironment L Bejarano, MJC Jordāo, JA Joyce Cancer discovery 11 (4), 933-959, 2021 | 808 | 2021 |
| Non-cell-autonomous tumor suppression by p53 A Lujambio, L Akkari, J Simon, D Grace, DF Tschaharganeh, JE Bolden, ... Cell 153 (2), 449-460, 2013 | 770 | 2013 |
| Microenvironmental regulation of therapeutic response in cancer F Klemm, JA Joyce Trends in cell biology 25 (4), 198-213, 2015 | 761 | 2015 |
| Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis JA Joyce, A Baruch, K Chehade, N Meyer-Morse, E Giraudo, FY Tsai, ... Cancer cell 5 (5), 443-453, 2004 | 738 | 2004 |
| Therapeutic targeting of the tumor microenvironment JA Joyce Cancer cell 7 (6), 513-520, 2005 | 703 | 2005 |
| Challenges to curing primary brain tumours K Aldape, KM Brindle, L Chesler, R Chopra, A Gajjar, MR Gilbert, ... Nature reviews Clinical oncology 16 (8), 509-520, 2019 | 693 | 2019 |
| Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ... Cell 181 (7), 1643-1660. e17, 2020 | 648 | 2020 |
| Distinct roles for cysteine cathepsin genes in multistage tumorigenesis V Gocheva, W Zeng, D Ke, D Klimstra, T Reinheckel, C Peters, ... Genes & development 20 (5), 543-556, 2006 | 641 | 2006 |
| Proteolytic networks in cancer SD Mason, JA Joyce Trends in cell biology 21 (4), 228-237, 2011 | 620 | 2011 |
| Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response OC Olson, JA Joyce Nature Reviews Cancer 15 (12), 712-729, 2015 | 608 | 2015 |
| The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas DF Quail, RL Bowman, L Akkari, ML Quick, AJ Schuhmacher, JT Huse, ... Science 352 (6288), aad3018, 2016 | 592 | 2016 |
| Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer T Shree, OC Olson, BT Elie, JC Kester, AL Garfall, K Simpson, ... Genes & development 25 (23), 2465-2479, 2011 | 591 | 2011 |
| Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies RL Bowman, F Klemm, L Akkari, SM Pyonteck, L Sevenich, DF Quail, ... Cell reports 17 (9), 2445-2459, 2016 | 550 | 2016 |
| The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth KE de Visser, JA Joyce Cancer Cell 41 (3), 374-403, 2023 | 549 | 2023 |
