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Taotao Sheng
Taotao Sheng
Duke-NUS Medical School
Verified email at duke-nus.edu.sg
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Year
AQP5 enriches for stem cells and cancer origins in the distal stomach
SH Tan, Y Swathi, S Tan, J Goh, R Seishima, K Murakami, M Oshima, ...
Nature 578 (7795), 437-443, 2020
1062020
A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers
A Fatehullah, Y Terakado, S Sagiraju, TL Tan, T Sheng, SH Tan, ...
Nature Cell Biology 23 (12), 1299-1313, 2021
412021
CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies
R Davies, L Liu, S Taotao, N Tuano, R Chaturvedi, KK Huang, C Itman, ...
Genome biology 22, 1-19, 2021
152021
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
M Xing, WF Ooi, J Tan, A Qamra, PH Lee, Z Li, C Xu, N Padmanabhan, ...
The Journal of clinical investigation 130 (6), 3005-3020, 2020
152020
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities
SWT Ho, T Sheng, M Xing, WF Ooi, C Xu, R Sundar, KK Huang, Z Li, ...
Gut 72 (2), 226-241, 2023
132023
Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression
KK Huang, H Ma, RHH Chong, T Uchihara, BSX Lian, F Zhu, T Sheng, ...
Cancer cell 41 (12), 2019-2037. e8, 2023
112023
Chromatin rewiring by mismatch repair protein MSH2 alters cell adhesion pathways and sensitivity to BET inhibition in gastric cancer
AM Nargund, C Xu, A Mandoli, A Okabe, GB Chen, KK Huang, T Sheng, ...
Cancer Research 82 (14), 2538-2551, 2022
82022
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer
T Sheng, SWT Ho, WF Ooi, C Xu, M Xing, N Padmanabhan, KK Huang, ...
Genome medicine 13, 1-25, 2021
82021
DEF: an automated dead-end filling approach based on quasi-endosymbiosis
L Liu, Z Zhang, T Sheng, M Chen
Bioinformatics 33 (3), 405-413, 2017
72017
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities
C Xu, KK Huang, JH Law, JS Chua, T Sheng, NM Flores, MP Pizzi, ...
Gut 72 (9), 1651-1663, 2023
62023
DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial
R Sundar, A Ng, H Zouridis, N Padmanabhan, T Sheng, S Zhang, MH Lee, ...
European Journal of Cancer 123, 48-57, 2019
52019
DNA methylation signature predictive of benefit from neoadjuvant chemotherapy in esophageal adenocarcinoma: Results from the MRC OEO2 phase III trial.
R Sundar, A Ng, H Zouridis, T Sheng, S Zhang, MH Lee, N Padmanabhan, ...
Journal of Clinical Oncology 37 (4_suppl), 43-43, 2019
22019
Author Correction: CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies
R Davies, L Liu, S Taotao, N Tuano, R Chaturvedi, KK Huang, C Itman, ...
Genome Biology 22, 1-2, 2021
12021
Abstract P28: Comprehensive Molecular Phenotyping of ARID1A-deficient Gastric Cancer Reveals Pervasive Epigenomic Reprogramming and Therapeutic …
C Xu, KK Huang, JH Law, JS Chua, T Sheng, NM Flores, MP Pizzi, ...
Cancer Research 84 (8_Supplement), P28-P28, 2024
2024
Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases
JJ Zhao, JCA Ong, S Srivastava, DKA Chia, H Ma, KK Huang, T Sheng, ...
bioRxiv, 2024.03. 21.585686, 2024
2024
Correction: Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer
AM Nargund, C Xu, A Mandoli, A Okabe, GB Chen, KK Huang, T Sheng, ...
Cancer Research 83 (5), 804-804, 2023
2023
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