| SLC transporters: structure, function, and drug discovery C Colas, PMU Ung, A Schlessinger Medchemcomm 7 (6), 1069-1081, 2016 | 189 | 2016 |
| Ligand discovery for the alanine-serine-cysteine transporter (ASCT2, SLC1A5) from homology modeling and virtual screening C Colas, C Grewer, NJ Otte, A Gameiro, T Albers, K Singh, H Shere, ... PLoS computational biology 11 (10), e1004477, 2015 | 77 | 2015 |
| Reevaluating the substrate specificity of the L-type amino acid transporter (LAT1) HC Chien, C Colas, K Finke, S Springer, L Stoner, AA Zur, B Venteicher, ... Journal of medicinal chemistry 61 (16), 7358-7373, 2018 | 72 | 2018 |
| The RESOLUTE consortium: unlocking SLC transporters for drug discovery G Superti-Furga, D Lackner, T Wiedmer, A Ingles-Prieto, B Barbosa, ... Nature reviews Drug discovery 19 (7), 429-430, 2020 | 71 | 2020 |
| Mutations in the Na+/Citrate Cotransporter NaCT (SLC13A5) in Pediatric Patients with Epilepsy and Developmental Delay J Klotz, BE Porter, C Colas, A Schlessinger, AM Pajor Molecular Medicine 22 (1), 310-321, 2016 | 64 | 2016 |
| LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs E Augustyn, K Finke, AA Zur, L Hansen, N Heeren, HC Chien, L Lin, ... Bioorganic & medicinal chemistry letters 26 (11), 2616-2621, 2016 | 48 | 2016 |
| LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates AA Zur, HC Chien, E Augustyn, A Flint, N Heeren, K Finke, C Hernandez, ... Bioorganic & medicinal chemistry letters 26 (20), 5000-5006, 2016 | 43 | 2016 |
| Structure activity relationships of benzylproline-derived inhibitors of the glutamine transporter ASCT2 K Singh, R Tanui, A Gameiro, G Eisenberg, C Colas, A Schlessinger, ... Bioorganic & medicinal chemistry letters 27 (3), 398-402, 2017 | 34 | 2017 |
| Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC MS Prevost, S Delarue-Cochin, J Marteaux, C Colas, C Van Renterghem, ... Journal of medicinal chemistry 56 (11), 4619-4630, 2013 | 32 | 2013 |
| Structure-Based Identification of Inhibitors for the SLC13 Family of Na+/Dicarboxylate Cotransporters C Colas, AM Pajor, A Schlessinger Biochemistry 54 (31), 4900-4908, 2015 | 31 | 2015 |
| From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins S Desrat, C Remeur, C Geny, G Riviere, C Colas, V Dumontet, N Birlirakis, ... Chemical Communications 50 (62), 8593-8596, 2014 | 31 | 2014 |
| Homology modeling informs ligand discovery for the glutamine transporter ASCT2 RAA Garibsingh, NJ Otte, E Ndaru, C Colas, C Grewer, J Holst, ... Frontiers in chemistry 6, 279, 2018 | 28 | 2018 |
| Determinants of substrate and cation transport in the human Na+/dicarboxylate cotransporter NaDC3 A Schlessinger, NN Sun, C Colas, AM Pajor Journal of Biological Chemistry 289 (24), 16998-17008, 2014 | 28 | 2014 |
| ATP modulates SLC7A5 (LAT1) synergistically with cholesterol J Cosco, M Scalise, C Colas, M Galluccio, R Martini, F Rovella, T Mazza, ... Scientific Reports 10 (1), 1-15, 2020 | 23 | 2020 |
| Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures A Taly, C Colas, T Malliavin, A Blondel, M Nilges, PJ Corringer, D Joseph Journal of Molecular Graphics and Modelling 30, 100-109, 2011 | 20 | 2011 |
| Chemical modulation of the human oligopeptide transporter 1, hPepT1 C Colas, M Masuda, K Sugio, S Miyauchi, Y Hu, DE Smith, A Schlessinger Molecular pharmaceutics 14 (12), 4685-4693, 2017 | 19 | 2017 |
| Studies of structural determinants of substrate binding in the creatine Transporter (CreaT, SLC6A8) using molecular models C Colas, G Banci, R Martini, GF Ecker Scientific Reports 10 (1), 1-10, 2020 | 18 | 2020 |
| Effects of mutations and ligands on the thermostability of the L-arginine/agmatine antiporter AdiC and deduced insights into ligand-binding of human L-type amino acid transporters H Ilgü, JM Jeckelmann, C Colas, Z Ucurum, A Schlessinger, D Fotiadis International journal of molecular sciences 19 (3), 918, 2018 | 17 | 2018 |
| Virtual screening of the SAMPL4 blinded HIV integrase inhibitors dataset C Colas, BI Iorga Journal of computer-aided molecular design 28 (4), 455-462, 2014 | 17 | 2014 |
| Identification of mitochondrial toxicants by combined in silico and in vitro studies–A structure-based view on the adverse outcome pathway F Troger, J Delp, M Funke, W van der Stel, C Colas, M Leist, ... Computational Toxicology 14, 100123, 2020 | 15 | 2020 |
