The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature chemical biology 11 (8), 536-541, 2015 | 839 | 2015 |
Ruthenium‐catalyzed reactions—a treasure trove of atom‐economic transformations BM Trost, MU Frederiksen, MT Rudd Angewandte Chemie International Edition 44 (41), 6630-6666, 2005 | 584 | 2005 |
Palladium‐Catalyzed Asymmetric Allylation of Prochiral Nucleophiles: Synthesis of 3‐Allyl‐3‐Aryl Oxindoles BM Trost, MU Frederiksen Angewandte Chemie International Edition 44 (2), 308-310, 2005 | 239 | 2005 |
High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions D Hoepfner, SB Helliwell, H Sadlish, S Schuierer, I Filipuzzi, S Brachat, ... Microbiological research 169 (2-3), 107-120, 2014 | 164 | 2014 |
Dinuclear asymmetric Zn aldol additions: formal asymmetric synthesis of fostriecin BM Trost, MU Frederiksen, JPN Papillon, PE Harrington, S Shin, ... Journal of the American Chemical Society 127 (11), 3666-3667, 2005 | 164 | 2005 |
Glycale in der organischen Synthese: die Entwicklung umfassender Strategien zum Aufbau von Oligosacchariden und Glycokonjugaten mit biologischer Bedeutung SJ Danishefsky, MT Bilodeau Angewandte Chemie 108 (13‐14), 1482-1522, 1996 | 153 | 1996 |
Progress towards a public chemogenomic set for protein kinases and a call for contributions DH Drewry, CI Wells, DM Andrews, R Angell, H Al-Ali, AD Axtman, ... PloS one 12 (8), e0181585, 2017 | 152 | 2017 |
Ruthenium‐katalysierte Reaktionen–eine Schatzkiste für atomökonomische Umwandlungen BM Trost, MU Frederiksen, MT Rudd Angewandte Chemie 117 (41), 6788-6825, 2005 | 115 | 2005 |
The kinase chemogenomic set (KCGS): an open science resource for kinase vulnerability identification CI Wells, H Al-Ali, DM Andrews, CRM Asquith, AD Axtman, I Dikic, ... International journal of molecular sciences 22 (2), 566, 2021 | 80 | 2021 |
Gamma-lactams—A novel scaffold for highly potent and selective α7 nicotinic acetylcholine receptor agonists A Enz, D Feuerbach, MU Frederiksen, C Gentsch, K Hurth, W Müller, ... Bioorganic & Medicinal Chemistry Letters 19 (5), 1287-1291, 2009 | 52 | 2009 |
Asymmetric Carbon–Carbon Bond‐Forming Reactions: Asymmetric Allylic Alkylation Reactions BM Trost, C Lee Catalytic asymmetric synthesis, 593-649, 2000 | 51 | 2000 |
Systematic chemogenetic library assembly SM Canham, Y Wang, A Cornett, DS Auld, DK Baeschlin, M Patoor, ... Cell chemical biology 27 (9), 1124-1129, 2020 | 43 | 2020 |
Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization E Surdziel, I Clay, F Nigsch, A Thiemeyer, C Allard, G Hoffman, ... PLoS One 12 (8), e0183679, 2017 | 41 | 2017 |
Structure–activity relationships for selected sulfur-rich antifungal compounds FJ Baerlocher, RF Langler, MU Frederiksen, NM Georges, RD Witherell Australian journal of chemistry 52 (3), 167-172, 1999 | 33 | 1999 |
An integrated approach for identification and target validation of antifungal compounds active against Erg11p D Hoepfner, S Karkare, SB Helliwell, M Pfeifer, M Trunzer, ... Antimicrobial agents and chemotherapy 56 (8), 4233-4240, 2012 | 31 | 2012 |
IRF2 is a master regulator of human keratinocyte stem cell fate N Mercado, G Schutzius, C Kolter, D Estoppey, S Bergling, G Roma, ... Nature communications 10 (1), 4676, 2019 | 29 | 2019 |
Oxazine derivatives and their use in the treatment of neurological disorders P Holzer, R Machauer, M Tintelnot-Blomley US Patent 8,207,164, 2012 | 27* | 2012 |
Detecting S-adenosyl-L-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay Y Lin, H Fan, M Frederiksen, K Zhao, L Jiang, Z Wang, S Zhou, W Guo, ... Analytical biochemistry 423 (1), 171-177, 2012 | 25 | 2012 |
OBF1 and Oct factors control the germinal center transcriptional program S Song, C Cao, MA Choukrallah, F Tang, G Christofori, H Kohler, F Wu, ... Blood, The Journal of the American Society of Hematology 137 (21), 2920-2934, 2021 | 24 | 2021 |
1-aza-bicyclo [3.3. 1] nonanes D Feuerbach, W Müller, BL Roy, TJ Troxler, K Hurth, M Frederiksen US Patent 8,933,090, 2015 | 23 | 2015 |