| A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ... Cancer research 69 (10), 4277, 2009 | 303 | 2009 |
| Quinoline derivatives for modulating DNA methylation P Phiasivongsa, SG Redkar, S Gamage, D Brooke, W Denny, DJ Bearss, ... US Patent 7,939,546, 2011 | 81 | 2011 |
| Quinoline derivatives for modulating DNA methylation P Phiasivongsa, SG Redkar, S Gamage, D Brooke, W Denny, DJ Bearss, ... US Patent 7,790,746, 2010 | 69 | 2010 |
| Quinoline derivatives for modulating dna methylation P Phiasivongsa, SG Redkar, S Gamage, D Brooke, W Denny, DJ Bearss, ... US Patent App. 13/047,635, 2011 | 57 | 2011 |
| Quinoline derivatives for modulating dna methylation P Phiasivongsa, S Redkar, S Gamage, D Brooke, W Denny, DJ Bearss, ... US Patent App. 11/871,762, 2008 | 55 | 2008 |
| Quinoline derivatives for modulating dna methylation P Phiasivongsa, SG Redkar, S Gamage, D Brooke, W Denny, DJ Bearss, ... US Patent App. 12/556,510, 2010 | 51 | 2010 |
| Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3) JU Flanagan, GJ Atwell, DM Heinrich, DG Brooke, S Silva, LJM Rigoreau, ... Bioorganic & Medicinal Chemistry 22 (3), 967-977, 2014 | 46 | 2014 |
| Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2, 6-bisphosphatase 3 (PFKFB3) DG Brooke, EM van Dam, CKW Watts, A Khoury, MA Dziadek, H Brooks, ... Bioorganic & medicinal chemistry 22 (3), 1029-1039, 2014 | 42 | 2014 |
| 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: Highly Potent and Selective Inhibitors of the Type 5 17-β-Hydroxysteroid Dehydrogenase AKR1C3 SMF Jamieson, DG Brooke, D Heinrich, GJ Atwell, S Silva, EJ Hamilton, ... Journal of medicinal chemistry 55 (17), 7746-7758, 2012 | 40 | 2012 |
| The activity of SN33638, an inhibitor of AKR1C3, on testosterone and 17β-estradiol production and function in castration-resistant prostate cancer and ER-positive breast cancer YD Yin, M Fu, DG Brooke, DM Heinrich, WA Denny, SMF Jamieson Frontiers in oncology 4, 159, 2014 | 33 | 2014 |
| Structure–activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1 SA Gamage, DG Brooke, S Redkar, J Datta, ST Jacob, WA Denny Bioorganic & medicinal chemistry 21 (11), 3147-3153, 2013 | 25 | 2013 |
| Synthesis and in vitro evaluation of analogues of avocado-produced toxin (+)-(R)-persin in human breast cancer cells DG Brooke, EJ Shelley, CG Roberts, WA Denny, RL Sutherland, AJ Butt Bioorganic & medicinal chemistry 19 (23), 7033-7043, 2011 | 24 | 2011 |
| Antifouling activity of portimine, select semisynthetic analogues, and other microalga-derived spirocyclic imines DG Brooke, G Cervin, O Champeau, DT Harwood, H Pavia, AI Selwood, ... Biofouling 34 (8), 950-961, 2018 | 17 | 2018 |
| Total synthesis of hydroxystrobilurin A via Stille coupling DG Brooke, JC Morris Tetrahedron Letters 49 (15), 2414-2417, 2008 | 15 | 2008 |
| Microtubule-stabilizing properties of the avocado-derived toxins (+)-(R)-persin and (+)-(R)-tetrahydropersin in cancer cells and activity of related synthetic analogs JJ Field, A Kanakkanthara, DG Brooke, S Sinha, SD Pillai, WA Denny, ... Investigational new drugs 34, 277-289, 2016 | 10 | 2016 |
| Synthesis and Microtubule‐Destabilizing Activity of N‐Cyclopropyl‐4‐((3,4‐dihydroquinolin‐1(2H)‐yl)sulfonyl)benzamide and its Analogs JJ Field, AJ Singh, S Sinha, MR Rowe, WA Denny, DG Brooke, JH Miller Chemistry–An Asian Journal 14 (8), 1151-1157, 2019 | 1 | 2019 |
| Quinoline derivatives for modulating dna methylation DJ Bearss, D Brooke, W Denny, S Gamage, P Phiasivongsa, S Redkar, ... CA Patent App. 002,664,631 A, 2008 | 1 | 2008 |
| A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation … J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ... CANCER RESEARCH 83 (24), 4180-4180, 2023 | | 2023 |
| Retraction: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ... Cancer research 83 (24), 4180-4180, 2023 | | 2023 |
| RETRACTED: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ... Cancer Research 69 (10), 4277-4285, 2009 | | 2009 |
