Suppression-Replacement KCNQ1 Gene Therapy for Type 1 Long QT Syndrome SM Dotzler, CSJ Kim, WAC Gendron, W Zhou, D Ye, JM Bos, DJ Tester, ... Circulation 143 (14), 1411-1425, 2021 | 43 | 2021 |
Characterization of the CACNA1C-R518C missense mutation in the pathobiology of long-QT syndrome using human induced pluripotent stem cell cardiomyocytes shows action potential … SI Estes, D Ye, W Zhou, SM Dotzler, DJ Tester, JM Bos, CSJ Kim, ... Circulation: Genomic and Precision Medicine 12 (8), e002534, 2019 | 24 | 2019 |
Corrected QT interval–polygenic risk score and its contribution to type 1, type 2, and type 3 long-QT syndrome in probands and genotype-positive family members KL Turkowski, SM Dotzler, DJ Tester, JR Giudicessi, JM Bos, AD Speziale, ... Circulation: Genomic and Precision Medicine 13 (4), e002922, 2020 | 22 | 2020 |
MRAS Variants Cause Cardiomyocyte Hypertrophy in Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Additional Evidence for MRAS as a … EM Higgins, JM Bos, SM Dotzler, CS John Kim, MJ Ackerman Circulation: Genomic and Precision Medicine 12 (11), e002648, 2019 | 18 | 2019 |
Defensive perimeter in the central nervous system: predominance of astrocytes and astrogliosis during recovery from varicella-zoster virus encephalitis JE Carpenter, AC Clayton, KC Halling, DJ Bonthius, EM Buckingham, ... Journal of virology 90 (1), 379-391, 2016 | 17 | 2016 |
A phenotype-enhanced variant classification framework to decrease the burden of missense variants of uncertain significance in type 1 long QT syndrome S Bains, SM Dotzler, C Krijger, JR Giudicessi, D Ye, H Bikker, RK Rohatgi, ... Heart Rhythm 19 (3), 435-442, 2022 | 11 | 2022 |
Suppression and Replacement Gene Therapy for KCNH2-Mediated Arrhythmias S Bains, W Zhou, SM Dotzler, K Martinez, CSJ Kim, DJ Tester, D Ye, ... Circulation: Genomic and Precision Medicine 15 (6), e003719, 2022 | 4 | 2022 |
Triadin knockout syndrome is absent in a multi-center molecular autopsy cohort of sudden infant death syndrome and sudden unexplained death in the young and is extremely rare … DJ Clemens, B Gray, RD Bagnall, DJ Tester, SM Dotzler, JR Giudicessi, ... Circulation: Genomic and Precision Medicine 13 (4), e002731, 2020 | 4 | 2020 |
Cellular and electrophysiological characterization of triadin knockout syndrome using induced pluripotent stem cell-derived cardiomyocytes DJ Clemens, D Ye, L Wang, CSJ Kim, W Zhou, SM Dotzler, DJ Tester, ... Stem Cell Reports 18 (5), 1075-1089, 2023 | 2 | 2023 |
Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential MJ Stutzman, CSJ Kim, DJ Tester, SK Hamrick, SM Dotzler, JR Giudicessi, ... Stem Cell Reports 17 (9), 2023-2036, 2022 | 1 | 2022 |
BS-400-40 SUPPRESSION AND REPLACEMENT GENE THERAPY FOR KCNH2-MEDIATED ARRHYTHMIAS S Bains, W Zhou, SM Dotzler, K Martinez, CJ Kim, D Tester, MJ Ackerman Heart Rhythm 19 (5), S512-S513, 2022 | | 2022 |
EN-580-03 SUPPRESSION AND REPLACEMENT GENE THERAPY FOR KCNH2-MEDIATED ARRHYTHMIAS S Bains, W Zhou, SM Dotzler, K Martinez, CJ Kim, D Tester, MJ Ackerman Heart Rhythm 19 (5), S51, 2022 | | 2022 |
EN-510-02 SUPPRESSION AND REPLACEMENT GENE THERAPY FOR KCNH2-MEDIATED ARRHYTHMIAS S Bains, W Zhou, SM Dotzler, K Martinez, CJ Kim, D Tester, MJ Ackerman Heart Rhythm 19 (5), S99, 2022 | | 2022 |
Suppression and Replacement Gene Therapy for Type 2 Long QT Syndrome S Bains, S Dotzler, W Zhou, CSJ Kim, DJ Tester, MJ Ackerman Circulation 144 (Suppl_1), A14260-A14260, 2021 | | 2021 |
B-PO04-001 CHARACTERIZATION OF EXTREME N-TERMINAL RYR2 VARIANTS FOUND OUTSIDE CPVT1 VARIANT CLUSTER REGIONS SHOW CA2+ HANDLING ABNORMALITIES CONSISTENT WITH CLASSICAL CPVT MJ Stutzman, CJ Kim, SK Hamrick, DJ Clemens, SM Dotzler, D Ye, ... Heart Rhythm 18 (8), S280, 2021 | | 2021 |
B-AB08-02 SUPPRESSION-REPLACEMENT KCNQ1 GENE THERAPY FOR JERVELL AND LANGE-NIELSEN SYNDROME SM Dotzler, CJ Kim, WAC Gendron, W Zhou, D Ye, JM Bos, D Tester, ... Heart Rhythm 18 (8), S14, 2021 | | 2021 |
B-YIA2-02 CELLULAR AND ELECTROPHYSIOLOGICAL CHARACTERIZATION OF TRIADIN KNOCKOUT SYNDROME USING HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES DJ Clemens, D Ye, L Wang, CJ Kim, W Zhou, SM Dotzler, D Tester, ... Heart Rhythm 18 (8), S50, 2021 | | 2021 |
The QTc-Polygenic Risk Score (QTc-PRS) and its Contribution to Type 1, Type 2, and Type 3 Long QT Syndrome in Probands and Genotype-Positive Family Members. KL Turkowski, SM Dotzler, DJ Tester, JR Giudicessi, JM Bos, AD Speziale, ... Circulation. Genomic and Precision Medicine, 2020 | | 2020 |
Varicella Zoster: Virus and Disease SM Dotzler, C Grose eLS, 0 | | |