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Yuanyuan Si
Yuanyuan Si
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Cell-Free Biosynthesis to Evaluate Lasso Peptide Formation and Enzyme–Substrate Tolerance
Y Si, AM Kretsch, LM Daigh, MJ Burk, DA Mitchell
Journal of the American Chemical Society 143 (15), 5917-5927, 2021
482021
Antibacterial activity and mode of action of a sulfonamide-based class of oxaborole leucyl-tRNA-synthetase inhibitors
Y Si, S Basak, Y Li, J Merino, JN Iuliano, SG Walker, PJ Tonge
ACS infectious diseases 5 (7), 1231-1238, 2019
302019
Functional elucidation of TfuA in peptide backbone thioamidation
A Liu, Y Si, SH Dong, N Mahanta, HN Penkala, SK Nair, DA Mitchell
Nature chemical biology 17 (5), 585-592, 2021
222021
Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[18F]F-p-Aminobenzoic Acid
Y Li, F Daryaee, GE Yoon, D Noh, PM Smith-Jones, Y Si, SG Walker, ...
ACS infectious diseases 6 (8), 2249-2259, 2020
152020
Peptidase activation by a leader peptide-bound RiPP recognition element
AM Kretsch, MG Gadgil, AJ DiCaprio, SE Barrett, BL Kille, Y Si, L Zhu, ...
Biochemistry 62 (4), 956-967, 2023
112023
Structure-based design, synthesis, and biological evaluation of non-acyl sulfamate inhibitors of the adenylate-forming enzyme MenE
CE Evans, Y Si, JS Matarlo, Y Yin, JB French, PJ Tonge, DS Tan
Biochemistry 58 (14), 1918-1930, 2019
42019
Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity
MT Cifone, YL He, R Basu, N Wang, S Davoodi, LA Spagnuolo, Y Si, ...
Journal of medicinal chemistry 65 (24), 16510-16525, 2022
2022
Inhibitors of adenylate-forming enzyme mene
DS Tan, CE Evans, PJ Tonge, ML Boby, Y Si
US Patent App. 17/429,319, 2022
2022
Development and MOA Study of Antimicrobial Agents Inhibiting Selected Protein Targets
Y Si
State University of New York at Stony Brook, 2018
2018
Analogs of methyl 4-(4-chlorophenyl)-4-oxobut-2-enoate that inhibit MenB in the bacterial menaquinone biosynthesis pathway
Y Si, J Matarlo, F Daryaee, P Tonge
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
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Articles 1–10