Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models RU Svensson, SJ Parker, LJ Eichner, MJ Kolar, M Wallace, SN Brun, ... Nature medicine 22 (10), 1108-1119, 2016 | 425 | 2016 |
Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex JJ Howell, K Hellberg, M Turner, G Talbott, MJ Kolar, DS Ross, G Hoxhaj, ... Cell metabolism 25 (2), 463-471, 2017 | 351 | 2017 |
Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis P Chen, H Zuo, H Xiong, MJ Kolar, Q Chu, A Saghatelian, DJ Siegwart, ... Proceedings of the National Academy of Sciences 114 (3), 580-585, 2017 | 333 | 2017 |
Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence G Sulli, A Rommel, X Wang, MJ Kolar, F Puca, A Saghatelian, MV Plikus, ... Nature 553 (7688), 351-355, 2018 | 313 | 2018 |
SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism Y Oishi, NJ Spann, VM Link, ED Muse, T Strid, C Edillor, MJ Kolar, ... Cell metabolism 25 (2), 412-427, 2017 | 288 | 2017 |
Serine restriction alters sphingolipid diversity to constrain tumour growth T Muthusamy, T Cordes, MK Handzlik, L You, EW Lim, J Gengatharan, ... Nature 586 (7831), 790-795, 2020 | 176 | 2020 |
Palmitic acid hydroxystearic acids activate GPR40, which is involved in their beneficial effects on glucose homeostasis I Syed, J Lee, PM Moraes-Vieira, CJ Donaldson, A Sontheimer, P Aryal, ... Cell metabolism 27 (2), 419-427. e4, 2018 | 158 | 2018 |
Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals MJ Kolar, S Konduri, T Chang, H Wang, C McNerlin, L Ohlsson, M Härröd, ... Journal of Biological Chemistry 294 (27), 10698-10707, 2019 | 87 | 2019 |
AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs WH Parsons, MJ Kolar, SS Kamat, ABC III, JJ Hulce, E Saez, BB Kahn, ... Nature chemical biology 12 (5), 367-372, 2016 | 78 | 2016 |
Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ... Scientific reports 8 (1), 1218, 2018 | 76 | 2018 |
The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina D Chen, DL Chao, L Rocha, M Kolar, VA Nguyen Huu, M Krawczyk, ... Aging cell 19 (2), e13100, 2020 | 73 | 2020 |
A LC-MS–based workflow for measurement of branched fatty acid esters of hydroxy fatty acids T Zhang, S Chen, I Syed, M Ståhlman, MJ Kolar, EA Homan, Q Chu, ... Nature protocols 11 (4), 747-763, 2016 | 73 | 2016 |
Stereochemistry of endogenous palmitic acid ester of 9-hydroxystearic acid and relevance of absolute configuration to regulation AT Nelson, MJ Kolar, Q Chu, I Syed, BB Kahn, A Saghatelian, D Siegel Journal of the American Chemical Society 139 (13), 4943-4947, 2017 | 64 | 2017 |
Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipase MJ Kolar, SS Kamat, WH Parsons, EA Homan, T Maher, OD Peroni, ... Biochemistry 55 (33), 4636-4641, 2016 | 62 | 2016 |
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer S Mitra, JE Montgomery, MJ Kolar, G Li, KJ Jeong, B Peng, GL Verdine, ... Nature communications 8 (1), 660, 2017 | 56 | 2017 |
Faster protocol for endogenous fatty acid esters of hydroxy fatty acid (FAHFA) measurements MJ Kolar, AT Nelson, T Chang, ME Ertunc, MP Christy, L Ohlsson, ... Analytical chemistry 90 (8), 5358-5365, 2018 | 49 | 2018 |
FGF1 and insulin control lipolysis by convergent pathways G Sancar, S Liu, E Gasser, JG Alvarez, C Moutos, K Kim, T van Zutphen, ... Cell metabolism 34 (1), 171-183. e6, 2022 | 43 | 2022 |
Commensal Cutibacterium acnes induce epidermal lipid synthesis important for skin barrier function S Almoughrabie, L Cau, K Cavagnero, AM O’Neill, F Li, A Roso-Mares, ... Science Advances 9 (33), eadg6262, 2023 | 13 | 2023 |
Stereochemistry of linoleic acid esters of hydroxy linoleic acids H Wang, MJ Kolar, T Chang, J Rizo, S Konduri, C McNerlin, ... Organic letters 21 (19), 8080-8084, 2019 | 9 | 2019 |
Author correction: Blocking Zika virus vertical transmission P Mesci, A Macia, SM Moore, SA Shiryaev, A Pinto, CT Huang, L Tejwani, ... Scientific reports 8, 2018 | 3 | 2018 |