CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines AM Pesenacker, D Bending, S Ursu, Q Wu, K Nistala, LR Wedderburn Blood, The Journal of the American Society of Hematology 121 (14), 2647-2658, 2013 | 185 | 2013 |
Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis E Omoyinmi, R Hamaoui, A Pesenacker, K Nistala, H Moncrieffe, S Ursu, ... Rheumatology 51 (10), 1881-1886, 2012 | 88 | 2012 |
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation A Kennedy, E Waters, B Rowshanravan, C Hinze, C Williams, D Janman, ... Nature immunology 23 (9), 1365-1378, 2022 | 84 | 2022 |
Brief Report: T Cell Expression of Granulocyte–Macrophage Colony‐Stimulating Factor in Juvenile Arthritis Is Contingent Upon Th17 Plasticity C Piper, AM Pesenacker, D Bending, B Thirugnanabalan, H Varsani, ... Arthritis & Rheumatology 66 (7), 1955-1960, 2014 | 84 | 2014 |
Brief Report: T Cell Expression of Granulocyte–Macrophage Colony‐Stimulating Factor in Juvenile Arthritis Is Contingent Upon Th17 Plasticity C Piper, AM Pesenacker, D Bending, B Thirugnanabalan, H Varsani, ... Arthritis & rheumatology 66 (7), 1955-1960, 2014 | 84 | 2014 |
Hypomethylation at the regulatory T cell–specific demethylated region in CD25hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis D Bending, AM Pesenacker, S Ursu, Q Wu, H Lom, B Thirugnanabalan, ... The Journal of Immunology 193 (6), 2699-2708, 2014 | 83 | 2014 |
T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression SJ Patterson, AM Pesenacker, AY Wang, J Gillies, M Mojibian, K Morishita, ... The Journal of clinical investigation 126 (3), 1039-1051, 2016 | 76 | 2016 |
A regulatory T-cell gene signature is a specific and sensitive biomarker to identify children with new-onset type 1 diabetes AM Pesenacker, AY Wang, A Singh, J Gillies, Y Kim, CA Piccirillo, ... Diabetes 65 (4), 1031-1039, 2016 | 73 | 2016 |
Control of tissue‐localized immune responses by human regulatory T cells AM Pesenacker, R Broady, MK Levings European journal of immunology 45 (2), 333-343, 2015 | 67 | 2015 |
Tailoring the homing capacity of human Tregs for directed migration to sites of Th1‐inflammation or intestinal regions RE Hoeppli, KN MacDonald, P Leclair, VCW Fung, M Mojibian, J Gillies, ... American Journal of Transplantation 19 (1), 62-76, 2019 | 66 | 2019 |
CD86 is a selective CD28 ligand supporting FoxP3+ regulatory T cell homeostasis in the presence of high levels of CTLA-4 N Halliday, C Williams, A Kennedy, E Waters, AM Pesenacker, B Soskic, ... Frontiers in immunology 11, 600000, 2020 | 57 | 2020 |
Innate control of tissue-reparative human regulatory T cells AJ Lam, KN MacDonald, AM Pesenacker, SC Juvet, KA Morishita, ... The Journal of Immunology 202 (8), 2195-2209, 2019 | 41 | 2019 |
Characterization of regulatory T cells in obese omental adipose tissue in humans D Wu, JM Han, X Yu, AJ Lam, RE Hoeppli, AM Pesenacker, Q Huang, ... European journal of immunology 49 (2), 336-347, 2019 | 41 | 2019 |
Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity AJ Lam, DTS Lin, JK Gillies, P Uday, AM Pesenacker, MS Kobor, ... Cell Reports 36 (5), 2021 | 39 | 2021 |
T regulatory cells in childhood arthritis–novel insights AM Pesenacker, LR Wedderburn Expert Reviews in Molecular Medicine 15, e13, 2013 | 37 | 2013 |
Treg gene signatures predict and measure type 1 diabetes trajectory AM Pesenacker, V Chen, J Gillies, C Speake, AK Marwaha, A Sun, ... JCI insight 4 (6), 2019 | 35 | 2019 |
The role of FOXP3 in autoimmunity AM Pesenacker, L Cook, MK Levings Current opinion in immunology 43, 16-23, 2016 | 34 | 2016 |
Immunological characteristics and T‐cell receptor clonal diversity in children with systemic juvenile idiopathic arthritis undergoing T‐cell‐depleted autologous stem cell … Q Wu, AM Pesenacker, A Stansfield, D King, D Barge, HE Foster, ... Immunology 142 (2), 227-236, 2014 | 28 | 2014 |
A composite immune signature parallels disease progression across T1D subjects C Speake, SO Skinner, D Berel, E Whalen, MJ Dufort, WC Young, ... JCI insight 4 (23), 2019 | 15 | 2019 |
Therapeutic gene editing of T cells to correct CTLA-4 insufficiency TA Fox, BC Houghton, L Petersone, E Waters, NM Edner, A McKenna, ... Science Translational Medicine 14 (668), eabn5811, 2022 | 14 | 2022 |