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Karl R Koehler
Karl R Koehler
Boston Children's Hospital/Harvard Medical School
Verified email at childrens.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
KR Koehler, AM Mikosz, AI Molosh, D Patel, E Hashino
Nature 500 (7461), 217-221, 2013
4102013
Hair-bearing human skin generated entirely from pluripotent stem cells
J Lee, CC Rabbani, H Gao, MR Steinhart, BM Woodruff, ZE Pflum, A Kim, ...
Nature 582 (7812), 399-404, 2020
2792020
Generation of inner ear organoids containing functional hair cells from human pluripotent stem cells
KR Koehler, J Nie, E Longworth-Mills, XP Liu, J Lee, JR Holt, E Hashino
Nature biotechnology 35 (6), 583-589, 2017
2762017
3D mouse embryonic stem cell culture for generating inner ear organoids
KR Koehler, E Hashino
Nature protocols 9 (6), 1229-1244, 2014
1442014
Hair follicle development in mouse pluripotent stem cell-derived skin organoids
J Lee, R Bӧscke, PC Tang, BH Hartman, S Heller, KR Koehler
Cell reports 22 (1), 242-254, 2018
1412018
Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3
T Kondo, AJ Matsuoka, A Shimomura, KR Koehler, RJ Chan, JM Miller, ...
Stem cells 29 (5), 836-846, 2011
1042011
Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells
XP Liu, KR Koehler, AM Mikosz, E Hashino, JR Holt
Nature communications 7 (1), 11508, 2016
972016
Modulation of Wnt signaling enhances inner ear organoid development in 3D culture
RE DeJonge, XP Liu, CR Deig, S Heller, KR Koehler, E Hashino
PloS one 11 (9), e0162508, 2016
632016
Defective Tmprss3-associated hair cell degeneration in inner ear organoids
PC Tang, J Nie, J Lee, AA Roth, KT Booth, KR Koehler, E Hashino, ...
Stem Cell Reports 13 (1), 147-162, 2019
592019
Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells
KR Koehler, P Tropel, JW Theile, T Kondo, TR Cummins, S Viville, ...
BMC neuroscience 12, 1-14, 2011
552011
Building inner ears: recent advances and future challenges for in vitro organoid systems
WH van der Valk, MR Steinhart, J Zhang, KR Koehler
Cell Death & Differentiation 28 (1), 24-34, 2021
422021
Generating inner ear organoids from mouse embryonic stem cells
E Longworth-Mills, KR Koehler, E Hashino
Embryonic Stem Cell Protocols, 391-406, 2016
412016
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53
S Vemula, J Shi, RS Mali, P Ma, Y Liu, P Hanneman, KR Koehler, ...
Blood, The Journal of the American Society of Hematology 120 (14), 2868-2878, 2012
412012
Skin organoids: A new human model for developmental and translational research
J Lee, KR Koehler
Experimental dermatology 30 (4), 613-620, 2021
392021
Management of mandible fracture in 150 children across 7 years in a US tertiary care hospital
R Kao, CC Rabbani, JM Patel, SM Parkhurst, AV Mantravadi, JY Ting, ...
JAMA Facial Plastic Surgery 21 (5), 414-418, 2019
352019
Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells
J Lee, WH Van Der Valk, SA Serdy, CC Deakin, J Kim, AP Le, KR Koehler
Nature protocols 17 (5), 1266-1305, 2022
332022
Directed differentiation of mouse embryonic stem cells into inner ear sensory epithelia in 3D culture
J Nie, KR Koehler, E Hashino
Organ Regeneration: 3D Stem Cell Culture & Manipulation, 67-83, 2017
242017
Stem cells and gene therapy in progressive hearing loss: the state of the art
A Nourbakhsh, BM Colbert, E Nisenbaum, A El-Amraoui, DM Dykxhoorn, ...
Journal of the Association for Research in Otolaryngology 22, 95-105, 2021
232021
Review of genotype-phenotype correlations in Usher syndrome
E Nisenbaum, TP Thielhelm, A Nourbakhsh, D Yan, SH Blanton, Y Shu, ...
Ear and hearing 43 (1), 1-8, 2022
202022
Dynamic click hydrogels for xeno‐free culture of induced pluripotent stem cells
MR Arkenberg, NH Dimmitt, HC Johnson, KR Koehler, CC Lin
Advanced biosystems 4 (11), 2000129, 2020
182020
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