| Structure of a c-kit product complex reveals the basis for kinase transactivation CD Mol, KB Lim, V Sridhar, H Zou, EYT Chien, BC Sang, J Nowakowski, ... Journal of Biological Chemistry 278 (34), 31461-31464, 2003 | 314 | 2003 |
| Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus RA Love, O Brodsky, MJ Hickey, PA Wells, CN Cronin Journal of virology 83 (9), 4395-4403, 2009 | 301 | 2009 |
| Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1 ME Schnute, MD McReynolds, T Kasten, M Yates, G Jerome, JW Rains, ... Biochemical Journal 444 (1), 79-88, 2012 | 291 | 2012 |
| Axitinib effectively inhibits BCR-ABL1 (T315I) with a distinct binding conformation T Pemovska, E Johnson, M Kontro, GA Repasky, J Chen, P Wells, ... Nature 519 (7541), 102-105, 2015 | 267 | 2015 |
| Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography J Nowakowski, CN Cronin, DE McRee, MW Knuth, CG Nelson, ... Structure 10 (12), 1659-1667, 2002 | 251 | 2002 |
| Role of arginine-292 in the substrate specificity of aspartate aminotransferase as examined by site-directed mutagenesis CN Cronin, JF Kirsch Biochemistry 27 (12), 4572-4579, 1988 | 132 | 1988 |
| Structures of the flavocytochrome p-cresol methylhydroxylase and its enzyme-substrate complex: gated substrate entry and proton relays support the proposed catalytic mechanism LM Cunane, ZW Chen, N Shamala, FS Mathews, CN Cronin, WS McIntire Journal of molecular biology 295 (2), 357-374, 2000 | 101 | 2000 |
| The enzymes of the classical pentose phosphate pathway display differential activities in procyclic and bloodstream forms of Trypanosoma brucei CN Cronín, DP Nolan, HP Voorheis FEBS letters 244 (1), 26-30, 1989 | 96 | 1989 |
| Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity AA Thompson, A Zou, J Yan, R Duggal, W Hao, D Molina, CN Cronin, ... Biochemistry 48 (5), 906-916, 2009 | 78 | 2009 |
| Purification and regulatory properties of phosphofructokinase from Trypanosoma (Trypanozoon) brucei brucei CN Cronin, KF Tipton Biochemical Journal 227 (1), 113-124, 1985 | 76 | 1985 |
| Reversal of substrate charge specificity by site-directed mutagenesis of aspartate aminotransferase CN Cronin, BA Malcolm, JF Kirsch Journal of the American Chemical Society 109 (7), 2222-2223, 1987 | 70 | 1987 |
| Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders Y Cai, CN Cronin, AG Engel, K Ohno, LB Hersh, DW Rodgers The EMBO journal 23 (10), 2047-2058, 2004 | 69 | 2004 |
| Isolation and characterization of an evolutionary precursor of human monoamine oxidases A and B SO Sablin, V Yankovskaya, S Bernard, CN Cronin, TP Singer European journal of biochemistry 253 (1), 270-279, 1998 | 62 | 1998 |
| Production of selenomethionyl‐derivatized proteins in baculovirus‐infected insect cells CN Cronin, KB Lim, J Rogers Protein Science 16 (9), 2023-2029, 2007 | 54 | 2007 |
| Discovery of allosteric, potent, subtype selective, and peripherally restricted TrkA kinase inhibitors SK Bagal, K Omoto, DC Blakemore, PJ Bungay, JG Bilsland, PJ Clarke, ... Journal of medicinal chemistry 62 (1), 247-265, 2018 | 49 | 2018 |
| cDNA Cloning, Recombinant Expression, and Site‐Directed Mutagenesis of Bovine Liver Carnitine Octanoyltransferase: Arg505 Binds the Carboxylate Group of Carnitine CN Cronin European journal of biochemistry 247 (3), 1029-1037, 1997 | 47 | 1997 |
| Effects of Noncovalent and Covalent FAD Binding on the Redox and Catalytic Properties of p-Cresol Methylhydroxylase I Efimov, CN Cronin, WS McIntire Biochemistry 40 (7), 2155-2166, 2001 | 45 | 2001 |
| Genomic Cloning and Sequence Analyses of the Bovine α‐, βA‐ and βB‐Inhibin/activin Genes: Identification of Transcription Factor AP‐2‐Binding Sites in the 5 … DA Thompson, CN Cronin, F Martin European Journal of Biochemistry 226 (3), 751-764, 1994 | 43 | 1994 |
| Redesign of choline acetyltransferase specificity by protein engineering CN Cronin Journal of Biological Chemistry 273 (38), 24465-24469, 1998 | 42 | 1998 |
| Organization and sequences of p-hydroxybenzaldehyde dehydrogenase and other plasmid-encoded genes for early enzymes of the p-cresol degradative pathway in Pseudomonas putida … CN Cronin, J Kim, JH Fuller, X Zhang, WS Mcintire DNA Sequence 10 (1), 7-17, 1999 | 40 | 1999 |
