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Ramya Kumar
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Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman, CV Bruggen, CJ Grimme, ...
Chemical Reviews 121 (18), 11527-11652, 2021
1552021
Efficient polymer-mediated delivery of gene-editing ribonucleoprotein payloads through combinatorial design, parallelized experimentation, and machine learning
R Kumar, N Le, Z Tan, ME Brown, S Jiang, TM Reineke
ACS nano 14 (12), 17626-17639, 2020
692020
Block polymer micelles enable CRISPR/Cas9 ribonucleoprotein delivery: physicochemical properties affect packaging mechanisms and gene editing efficiency
Z Tan, Y Jiang, MS Ganewatta, R Kumar, A Keith, K Twaroski, T Pengo, ...
Macromolecules 52 (21), 8197-8206, 2019
512019
Enhancement of the propagation of human embryonic stem cells by modifications in the gel architecture of PMEDSAH polymer coatings
X Qian, LG Villa-Diaz, R Kumar, J Lahann, PH Krebsbach
Biomaterials 35 (36), 9581-9590, 2014
392014
Cationic bottlebrush polymers outperform linear polycation analogues for pDNA delivery and gene expression
RJ Dalal, R Kumar, M Ohnsorg, M Brown, TM Reineke
ACS Macro Letters 10 (7), 886-893, 2021
372021
Combinatorial polycation synthesis and causal machine learning reveal divergent polymer design rules for effective pDNA and ribonucleoprotein delivery
R Kumar, N Le, F Oviedo, ME Brown, TM Reineke
Jacs Au 2 (2), 428-442, 2022
272022
Predictive Model for the Design of Zwitterionic Polymer Brushes: A Statistical Design of Experiments Approach
R Kumar, J Lahann
ACS applied materials & interfaces, 2016
142016
Polylutidines: Multifunctional Surfaces through Vapor‐Based Polymerization of Substituted Pyridinophanes
F Bally‐Le Gall, C Hussal, J Kramer, K Cheng, R Kumar, T Eyster, A Baek, ...
Chemistry–A European Journal 23 (54), 13342-13350, 2017
122017
Substrate-independent micropatterning of polymer brushes based on photolytic deactivation of chemical vapor deposition based surface-initiated atom-transfer radical …
R Kumar, A Welle, F Becker, I Kopyeva, J Lahann
ACS applied materials & interfaces 10 (38), 31965-31976, 2018
102018
pH-Responsive Aminomethyl Functionalized Poly(p-xylylene) Coatings by Chemical Vapor Deposition Polymerization
M. Koenig, R. Kumar, C. Hussal, V. Trouillet, L. Barner, J. Lahann
Macromolecular Chemistry and Physics, 2017
82017
Carbohydrate‐based polymer brushes prevent viral adsorption on electrostatically heterogeneous interfaces
R Kumar, D Kratzer, K Cheng, J Prisby, J Sugai, WV Giannobile, J Lahann
Macromolecular Rapid Communications 40 (1), 1800530, 2019
72019
Materiomically designed polymeric vehicles for nucleic acids: quo vadis?
R Kumar
ACS Applied Bio Materials 5 (6), 2507-2535, 2022
62022
Examining Nanoparticle Adsorption on Electrostatically “Patchy” Glycopolymer Brushes Using Real-Time ζ-Potential Measurements
R Kumar, I Kopyeva, K Cheng, K Liu, J Lahann
Langmuir 33 (25), 6322-6332, 2017
52017
Facile synthesis of GalNAc monomers and block polycations for hepatocyte gene delivery
MR Bockman, RJ Dalal, R Kumar, TM Reineke
Polymer Chemistry 12 (28), 4063-4071, 2021
42021
Machine Learning Elucidates Design Features of Plasmid DNA Lipid Nanoparticles for Cell Type-Preferential Transfection
L Cheng, Y Zhu, J Ma, A Aggarwal, WH Toh, C Shin, ...
bioRxiv, 2023.12. 07.570602, 2023
12023
Identification of a novel, MSC-induced macrophage subtype via single-cell sequencing: implications for intervertebral disc degeneration therapy
J Koroth, C Chitwood, R Kumar, WH Lin, BT Reves, T Boyce, TM Reineke, ...
Frontiers in Cell and Developmental Biology 11, 1286011, 2024
2024
Poly (L-glutamic acid) augments the transfection performance of lipophilic polycations by overcoming tradeoffs among cytotoxicity, pDNA delivery efficiency, and serum stability
RP Sekar, JL Lawson, ARE Wright, C McGrath, C Schadeck, P Kumar, ...
2024
Copolymers for intracellular therapeutic nucleic acid payload delivery
T Reineke, N Le, Z Tan, R Kumar
US Patent App. 18/000,258, 2023
2023
Biomaterials: Graduate Student Award Session
K Lampe, R Kumar, N Shah
2022 AIChE Annual Meeting, 2022
2022
Substrate-Independent Micropatterning of Polymer Brushes Based on Photolytic Deactivation of Chemical Vapor Deposition Based Surface-Initiated Atom-Transfer Radical …
R Kumar, A Welle, F Becker, I Kopyeva, J Lahann
ACS APPLIED MATERIALS & INTERFACES 10 (44), 38656-38658, 2018
2018
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