| mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013 | 793 | 2013 |
| mTOR coordinates protein synthesis, mitochondrial activity and proliferation M Morita, SP Gravel, L Hulea, O Larsson, M Pollak, J St-Pierre, ... Cell cycle 14 (4), 473-480, 2015 | 506 | 2015 |
| AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species RC Rabinovitch, B Samborska, B Faubert, EH Ma, SP Gravel, ... Cell reports 21 (1), 1-9, 2017 | 470 | 2017 |
| Metformin directly acts on mitochondria to alter cellular bioenergetics S Andrzejewski, SP Gravel, M Pollak, J St-Pierre Cancer & metabolism 2, 1-14, 2014 | 456 | 2014 |
| nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs V Gandin, L Masvidal, L Hulea, SP Gravel, M Cargnello, S McLaughlan, ... Genome research 26 (5), 636-648, 2016 | 219 | 2016 |
| PGC-1α supports glutamine metabolism in breast cancer S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ... Cancer & metabolism 1, 1-11, 2013 | 170 | 2013 |
| Serine Deprivation Enhances Antineoplastic Activity of Biguanides SP Gravel, L Hulea, N Toban, E Birman, MJ Blouin, M Zakikhani, Y Zhao, ... Cancer research 74 (24), 7521-7533, 2014 | 140 | 2014 |
| ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ... Nature communications 7 (1), 12156, 2016 | 118 | 2016 |
| Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation A Bibeau-Poirier, SP Gravel, JF Clément, S Rolland, G Rodier, ... The Journal of Immunology 177 (8), 5059-5067, 2006 | 118 | 2006 |
| Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association JF Clément, A Bibeau-Poirier, SP Gravel, N Grandvaux, É Bonneil, ... Journal of virology 82 (8), 3984-3996, 2008 | 114 | 2008 |
| The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IκB kinase complex A Douillette, A Bibeau-Poirier, SP Gravel, JF Clément, V Chénard, ... Journal of Biological Chemistry 281 (19), 13275-13284, 2006 | 101 | 2006 |
| The PGC-1α/ERRα axis represses one-carbon metabolism and promotes sensitivity to anti-folate therapy in breast cancer E Audet-Walsh, DJ Papadopoli, SP Gravel, T Yee, G Bridon, M Caron, ... Cell reports 14 (4), 920-931, 2016 | 89 | 2016 |
| Translational and HIF-1α-dependent metabolic reprogramming underpin metabolic plasticity and responses to kinase inhibitors and biguanides L Hulea, SP Gravel, M Morita, M Cargnello, O Uchenunu, YK Im, ... Cell metabolism 28 (6), 817-832. e8, 2018 | 73 | 2018 |
| RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma PPR Thibault Houles, Simon-Pierre Gravel, Geneviève Lavoie, Sejeong Shin ... Cancer Research, 2018 | 59 | 2018 |
| The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and … O Mamer, SP Gravel, L Choiniere, V Chénard, J St-Pierre, D Avizonis Metabolomics 9, 1019-1030, 2013 | 55 | 2013 |
| LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis MC Poffenberger, A Metcalfe-Roach, E Aguilar, J Chen, BE Hsu, ... Science 361 (6400), 406-411, 2018 | 53 | 2018 |
| Roles of an IκB kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells: a molecular link in pathogen-induced proatherosclerotic conditions SP Gravel, MJ Servant Journal of Biological Chemistry 280 (9), 7477-7486, 2005 | 50 | 2005 |
| Stable isotope tracer analysis in isolated mitochondria from mammalian systems SP Gravel, S Andrzejewski, D Avizonis, J St-Pierre Metabolites 4 (2), 166-183, 2014 | 37 | 2014 |
| Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs C Thivierge, HW Tseng, VK Mayya, C Lussier, SP Gravel, TF Duchaine Nucleic acids research 46 (19), 10340-10352, 2018 | 30 | 2018 |
| Deciphering the dichotomous effects of PGC-1α on tumorigenesis and metastasis SP Gravel Frontiers in Oncology 8, 75, 2018 | 30 | 2018 |
Michael PollakMcGill UniversityVerified email at mcgill.ca
