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Miklos Sahin-Toth
Miklos Sahin-Toth
Professor of Surgery, UCLA
Verified email at mednet.ucla.edu
Title
Cited by
Cited by
Year
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis
J Rosendahl, H Witt, R Szmola, E Bhatia, B Ózsvári, O Landt, HU Schulz, ...
Nature genetics 40 (1), 78-82, 2008
5042008
Cys‐scanning mutagenesis: a novel approach to structure—function relationships in polytopic membrane proteins
S Frillingos, M Sahin‐Tóth, J Wu, HR Kaback
The FASEB Journal 12 (13), 1281-1299, 1998
4301998
The kamikaze approach to membrane transport
HR Kaback, M Sahin-Tóth, AB Weinglass
Nature reviews Molecular cell biology 2 (8), 610-620, 2001
3482001
Variants in CPA1 are strongly associated with early onset chronic pancreatitis
H Witt, S Beer, J Rosendahl, JM Chen, GR Chandak, A Masamune, ...
Nature genetics 45 (10), 1216-1220, 2013
3222013
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis
H Witt, M Sahin-Tóth, O Landt, JM Chen, T Kähne, JPH Drenth, Z Kukor, ...
Nature genetics 38 (6), 668-673, 2006
2842006
Prospective, multicentre, nationwide clinical data from 600 cases of acute pancreatitis
A Párniczky, B Kui, A Szentesi, A Balázs, Á Szűcs, D Mosztbacher, ...
PloS one 11 (10), e0165309, 2016
2652016
Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen
M Sahin-Tóth, M Tóth
Biochemical and biophysical research communications 278 (2), 286-289, 2000
2582000
Genetics, cell biology, and pathophysiology of pancreatitis
J Mayerle, M Sendler, E Hegyi, G Beyer, MM Lerch, M Sahin-Tóth
Gastroenterology 156 (7), 1951-1968. e1, 2019
2542019
Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis
J Maléth, A Balázs, P Pallagi, Z Balla, B Kui, M Katona, L Judák, I Németh, ...
Gastroenterology 148 (2), 427-439. e16, 2015
2102015
Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y
R Szmola, M Sahin-Tóth
Proceedings of the National Academy of Sciences 104 (27), 11227-11232, 2007
1972007
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122→ Cys) that alters autoactivation and autodegradation of cationic trypsinogen
P Simon, FU Weiss, M Sahin-Tóth, M Parry, O Nayler, B Lenfers, ...
Journal of Biological Chemistry 277 (7), 5404-5410, 2002
1812002
Human cationic trypsinogen: role of Asn-21 in zymogen activation and implications in hereditary pancreatitis
M Sahin-Tóth
Journal of Biological Chemistry 275 (30), 22750-22755, 2000
1802000
Hereditary pancreatitis caused by mutation‐induced misfolding of human cationic trypsinogen: a novel disease mechanism
É Kereszturi, R Szmola, Z Kukor, P Simon, F Ulrich Weiss, MM Lerch, ...
Human mutation 30 (4), 575-582, 2009
1762009
Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors
R Szmola, Z Kukor, M Sahin-Tóth
Journal of Biological Chemistry 278 (49), 48580-48589, 2003
1702003
Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of …
JM Löhr, R Faissner, D Koczan, P Bewerunge, C Bassi, B Brors, R Eils, ...
Official journal of the American College of Gastroenterology| ACG 105 (9 …, 2010
1692010
Functional interactions between putative intramembrane charged residues in the lactose permease of Escherichia coli.
M Sahin-Toth, RL Dunten, A Gonzalez, HR Kaback
Proceedings of the National Academy of Sciences 89 (21), 10547-10551, 1992
1671992
Genetic risk in chronic pancreatitis: the trypsin-dependent pathway
E Hegyi, M Sahin-Tóth
Digestive diseases and sciences 62 (7), 1692-1701, 2017
1662017
Properties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli.
M Sahin-Toth, MC Lawrence, HR Kaback
Proceedings of the National Academy of Sciences 91 (12), 5421-5425, 1994
1641994
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice
T Wartmann, J Mayerle, T Kähne, M Sahin–Tóth, M Ruthenbürger, ...
Gastroenterology 138 (2), 726-737, 2010
1562010
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis
N Teich, J Rosendahl, M Tóth, J Mössner, M Sahin‐Tóth
Human mutation 27 (8), 721-730, 2006
1542006
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