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Commensal bacteria make GPCR ligands that mimic human signalling molecules LJ Cohen, D Esterhazy, SH Kim, C Lemetre, RR Aguilar, EA Gordon, ... Nature 549 (7670), 48-53, 2017 | 416 | 2017 |
Microbiota modulate sympathetic neurons via a gut–brain circuit PA Muller, M Schneeberger, F Matheis, P Wang, Z Kerner, A Ilanges, ... Nature 583 (7816), 441-446, 2020 | 273 | 2020 |
Lactose drives Enterococcus expansion to promote graft-versus-host disease CK Stein-Thoeringer, KB Nichols, A Lazrak, MD Docampo, ... Science 366 (6469), 1143-1149, 2019 | 256 | 2019 |
Impact of gut colonization with butyrate-producing microbiota on respiratory viral infection following allo-HCT BW Haak, ER Littmann, JL Chaubard, AJ Pickard, E Fontana, F Adhi, ... Blood, The Journal of the American Society of Hematology 131 (26), 2978-2986, 2018 | 223 | 2018 |
Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification MT Sorbara, K Dubin, ER Littmann, TU Moody, E Fontana, R Seok, ... Journal of Experimental Medicine 216 (1), 84-98, 2019 | 173 | 2019 |
Mapping interactions of microbial metabolites with human G-protein-coupled receptors DA Colosimo, JA Kohn, PM Luo, FJ Piscotta, SM Han, AJ Pickard, A Rao, ... Cell host & microbe 26 (2), 273-282. e7, 2019 | 125 | 2019 |
The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD KA Markey, J Schluter, ALC Gomes, ER Littmann, AJ Pickard, BP Taylor, ... Blood 136 (1), 130-136, 2020 | 110 | 2020 |
Nutritional support from the intestinal microbiota improves hematopoietic reconstitution after bone marrow transplantation in mice A Staffas, MB da Silva, AE Slingerland, A Lazrak, CJ Bare, CD Holman, ... Cell host & microbe 23 (4), 447-457. e4, 2018 | 108 | 2018 |
Comparison of topical and intravenous tranexamic acid for total knee replacement: a randomized double-blinded controlled study of effects on tranexamic acid levels and … KM Jules-Elysee, A Tseng, TP Sculco, LR Baaklini, AS McLawhorn, ... The Journal of bone and joint surgery. American volume 101 (23), 2120, 2019 | 72 | 2019 |
Functionalized tyrosine kinase inhibitors modified with precious metal electrophiles and methods associated therewith U Bierbach, M Yang, AJ Pickard US Patent App. 10/047,057, 2018 | 63* | 2018 |
The cell’s nucleolus: an emerging target for chemotherapeutic intervention AJ Pickard, U Bierbach ChemMedChem 8 (9), 1441-1449, 2013 | 58 | 2013 |
Redesigning the DNA‐Targeted Chromophore in Platinum–Acridine Anticancer Agents: A Structure–Activity Relationship Study AJ Pickard, F Liu, TF Bartenstein, LG Haines, KE Levine, GL Kucera, ... Chemistry–A European Journal 20 (49), 16174-16187, 2014 | 52 | 2014 |
Replacement of a Thiourea with an Amidine Group in a Monofunctional Platinum–Acridine Antitumor Agent. Effect on DNA Interactions, DNA Adduct Recognition and Repair H Kostrhunova, J Malina, AJ Pickard, J Stepankova, M Vojtiskova, ... Molecular pharmaceutics 8 (5), 1941-1954, 2011 | 41 | 2011 |
Synthesis, Reactivity, and Biological Activity of Gold (I) Complexes Modified with Thiourea-Functionalized Tyrosine Kinase Inhibitors M Yang, AJ Pickard, X Qiao, MJ Gueble, CS Day, GL Kucera, U Bierbach Inorganic chemistry 54 (7), 3316-3324, 2015 | 34 | 2015 |
Histone Methylation by Temozolomide; A Classic DNA Methylating Anticancer Drug T WANG, AJ PICKARD, JM GALLO Anticancer Research 36 (7), 3289-3299, 2016 | 32 | 2016 |
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity JGC van Hasselt, R Rahman, J Hansen, A Stern, JV Shim, Y Xiong, ... Nature communications 11 (1), 1-12, 2020 | 31 | 2020 |
Design of Enzymatically Cleavable Prodrugs of a Potent Platinum‐Containing Anticancer Agent S Ding, AJ Pickard, GL Kucera, U Bierbach Chemistry-A European Journal 20 (49), 16164-16173, 2014 | 30 | 2014 |
Intracerebral Distribution of the Oncometabolite d-2-Hydroxyglutarate in Mice Bearing Mutant Isocitrate Dehydrogenase Brain Tumors: Implications for Tumorigenesis AJ Pickard, ASW Sohn, TF Bartenstein, S He, Y Zhang, JM Gallo Frontiers in Oncology 6, 211, 2016 | 9 | 2016 |
Clinically-weighted transcriptomic signatures for protein kinase inhibitor associated cardiotoxicity JGC van Hasselt, J Hansen, Y Xiong, J Shim, A Pickard, G Jayaraman, ... bioRxiv, 075754, 2016 | 5 | 2016 |