| Modular organization and assembly of SWI/SNF family chromatin remodeling complexes N Mashtalir, AR D’Avino, BC Michel, J Luo, J Pan, JE Otto, HJ Zullow, ... Cell 175 (5), 1272-1288. e20, 2018 | 554 | 2018 |
| A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation BC Michel, AR D’Avino, SH Cassel, N Mashtalir, ZM McKenzie, ... Nature cell biology 20 (12), 1410-1420, 2018 | 310 | 2018 |
| SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters RT Nakayama, JL Pulice, AM Valencia, MJ McBride, ZM McKenzie, ... Nature genetics 49 (11), 1613-1623, 2017 | 258 | 2017 |
| Long-term maturation of human cortical organoids matches key early postnatal transitions A Gordon, SJ Yoon, SS Tran, CD Makinson, JY Park, J Andersen, ... Nature neuroscience 24 (3), 331-342, 2021 | 223 | 2021 |
| Chromatin regulatory mechanisms and therapeutic opportunities in cancer AM Valencia, C Kadoch Nature cell biology 21 (2), 152-161, 2019 | 183 | 2019 |
| Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence JA Belk, W Yao, N Ly, KA Freitas, YT Chen, Q Shi, AM Valencia, E Shifrut, ... Cancer Cell 40 (7), 768-786. e7, 2022 | 122 | 2022 |
| A structural model of the endogenous human BAF complex informs disease mechanisms N Mashtalir, H Suzuki, DP Farrell, A Sankar, J Luo, M Filipovski, ... Cell 183 (3), 802-817. e24, 2020 | 117 | 2020 |
| Recurrent SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF complex chromatin remodeling AM Valencia, CK Collings, HT Dao, RS Pierre, YC Cheng, J Huang, ... Cell 179 (6), 1342-1356. e23, 2019 | 85 | 2019 |
| Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome F Birey, MY Li, A Gordon, MV Thete, AM Valencia, O Revah, AM Paşca, ... Cell Stem Cell 29 (2), 248-264. e7, 2022 | 72 | 2022 |
| BICRA, a SWI/SNF complex member, is associated with BAF-disorder related phenotypes in humans and model organisms S Barish, TS Barakat, BC Michel, N Mashtalir, JB Phillips, AM Valencia, ... The American Journal of Human Genetics 107 (6), 1096-1112, 2020 | 38 | 2020 |
| The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma MJ McBride, N Mashtalir, EB Winter, HT Dao, M Filipovski, AR D’Avino, ... Nature structural & molecular biology 27 (9), 836-845, 2020 | 36 | 2020 |
| Chromatin dynamics in human brain development and disease AM Valencia, SP Pașca Trends in cell biology 32 (2), 98-101, 2022 | 13 | 2022 |
| Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders AM Valencia, A Sankar, PJ van der Sluijs, FK Satterstrom, J Fu, ... Nature Genetics 55 (8), 1400-1412, 2023 | 12 | 2023 |
| The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression G Mas, N Man, Y Nakata, C Martinez-Caja, D Karl, F Beckedorff, F Tamiro, ... The Journal of clinical investigation 133 (13), 2023 | 3 | 2023 |
| Intellectual disability-associated SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF chromatin remodeling AM Valencia, CK Collings, HT Dao, RS Pierre, YC Cheng, J Huang, ... Cell 179 (6), 1342, 2019 | 1 | 2019 |
| Compositions comprising modified smarcb1 and uses thereof C Kadoch, AM Valencia US Patent App. 17/770,464, 2022 | | 2022 |
| The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma (vol 27, pg 836, 2020) MJ McBride, N Mashtalir, EB Winter, HT Dao, M Filipovski, AR D'Avino, ... NATURE STRUCTURAL & MOLECULAR BIOLOGY 28 (1), 118-118, 2021 | | 2021 |
| The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks GM Martin, N Man, D Karl, C Martinez, S Duffort, H Itonaga, AK Mookhtiar, ... Blood 136, 13, 2020 | | 2020 |
| Biochemistry, Structure, and Function of SMARCB1-mutant mSWI/SNF Chromatin Remodeling Complexes in Human Disease AM Valencia | | 2020 |
| Genome-wide mistargeting of oncogenic SWI/SNF complexes in SMARCB1-deficient cancers R Nakayama, JL Pulice, AM Valencia, C Kadoch, M Matsumoto, ... CANCER SCIENCE 109, 1113-1113, 2018 | | 2018 |
Cigall KadochDana-Farber Cancer Institute, Harvard Medical School, Broad Institute of MIT and HarvardVerified email at dfci.harvard.edu
