Inhibition of RAS function through targeting an allosteric regulatory site R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ... Nature chemical biology 13 (1), 62-68, 2017 | 276 | 2017 |
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome EF Fang, Y Hou, S Lautrup, MB Jensen, B Yang, T SenGupta, D Caponio, ... Nature communications 10 (1), 5284, 2019 | 188 | 2019 |
Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair H Lu, RA Shamanna, JK de Freitas, M Okur, P Khadka, T Kulikowicz, ... Nature communications 8 (1), 2039, 2017 | 80 | 2017 |
Toward understanding genomic instability, mitochondrial dysfunction and aging NB Fakouri, Y Hou, TG Demarest, LS Christiansen, MN Okur, JG Mohanty, ... The FEBS Journal 286 (6), 1058-1073, 2019 | 67 | 2019 |
Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks KA Wong, J Wilson, A Russo, L Wang, MN Okur, X Wang, NP Martin, ... PLoS One 7 (4), e36023, 2012 | 67 | 2012 |
NAD+ Metabolism in Aging and Cancer TG Demarest, M Babbar, MN Okur, X Dan, DL Croteau, NB Fakouri, ... Annual Review of Cancer Biology 3, 105-130, 2019 | 66 | 2019 |
The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2 D Ash, V Sudhahar, SW Youn, MN Okur, A Das, JP O’Bryan, ... Nature communications 12 (1), 3091, 2021 | 49 | 2021 |
Proliferation defects and genome instability in cells lacking Cul4A D Kopanja, T Stoyanova, MN Okur, E Huang, S Bagchi, P Raychaudhuri Oncogene 28 (26), 2456-2465, 2009 | 45 | 2009 |
Current and emerging roles of Cockayne syndrome group B (CSB) protein V Tiwari, BA Baptiste, MN Okur, VA Bohr Nucleic acids research 49 (5), 2418-2434, 2021 | 39 | 2021 |
Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation MN Okur, JH Lee, W Osmani, R Kimura, TG Demarest, DL Croteau, ... Nucleic acids research 48 (5), 2473-2485, 2020 | 37 | 2020 |
Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome MN Okur, B Mao, R Kimura, S Haraczy, T Fitzgerald, ... npj Aging and Mechanisms of Disease 6 (1), 1, 2020 | 37* | 2020 |
Akt2 Stabilizes ATP7A, a Copper Transporter for SOD3 (Extracellular Superoxide Dismutase), in Vascular Smooth Muscles: Novel Mechanism to Limit Endothelial Dysfunction in Type … V Sudhahar, MN Okur, Z Bagi, JP O’bryan, N Hay, A Makino, VS Patel, ... Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA. 117.309819, 2017 | 37* | 2017 |
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling MN Okur, EF Fang, EM Fivenson, V Tiwari, DL Croteau, VA Bohr Aging Cell 19 (12), e13268, 2020 | 30 | 2020 |
Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis A Russo, MN Okur, M Bosland, JP O'Bryan Cancer letters 359 (2), 262-268, 2015 | 30 | 2015 |
Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging JH Lee, TG Demarest, M Babbar, EW Kim, MN Okur, S De, DL Croteau, ... Nucleic Acids Research 47 (16), 8548-8562, 2019 | 29 | 2019 |
Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction MN Okur, J Ooi, CW Fong, N Martinez, C Garcia-Dominguez, JM Rojas, ... Molecular and cellular biology 32 (4), 817-825, 2012 | 27 | 2012 |
Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase MN Okur, A Russo, JP O'Bryan Molecular and cellular biology 34 (2), 271-279, 2014 | 21 | 2014 |
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function V Sudhahar, MN Okur, JP O’Bryan, RD Minshall, D Fulton, M Ushio-Fukai, ... American Journal of Physiology-Cell Physiology 319 (5), C933-C944, 2020 | 18 | 2020 |
Regulation of the intranuclear distribution of the cockayne syndrome proteins T Iyama, MN Okur, T Golato, DR McNeill, H Lu, R Hamilton, A Raja, ... Scientific reports 8 (1), 17490, 2018 | 15* | 2018 |
Long‐term NAD+ supplementation prevents the progression of age‐related hearing loss in mice MN Okur, BD Sahbaz, R Kimura, U Manor, J Patel, JH Park, L Andrade, ... Aging Cell 22 (9), e13909, 2023 | 7 | 2023 |