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Alex Agelidis, MD, PhD
Alex Agelidis, MD, PhD
Medical Oncology Fellow at Scripps Health
Verified email at scrippshealth.org
Title
Cited by
Cited by
Year
The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis
M Onizawa, S Oshima, U Schulze-Topphoff, JA Oses-Prieto, T Lu, ...
Nature Immunology, 2015
2692015
Cell entry mechanisms of HSV: what we have learned in recent years
AM Agelidis, D Shukla
Future virology 10 (10), 1145-1154, 2015
2062015
Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme
TT Lu, M Onizawa, GE Hammer, EE Turer, Q Yin, E Damko, A Agelidis, ...
Immunity 38 (5), 896-905, 2013
1632013
Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation
AM Lobo, AM Agelidis, D Shukla
The ocular surface 17 (1), 40-49, 2019
1602019
Heparanase is a host enzyme required for herpes simplex virus-1 release from cells
SR Hadigal, AM Agelidis, GA Karasneh, TE Antoine, AM Yakoub, ...
Nature Communications 6, 2015
1352015
Viral activation of heparanase drives pathogenesis of herpes simplex virus-1
AM Agelidis, SR Hadigal, D Jaishankar, D Shukla
Cell reports 20 (2), 439-450, 2017
872017
Dysregulation of cell signaling by SARS-CoV-2
RK Suryawanshi, R Koganti, A Agelidis, CD Patil, D Shukla
Trends in microbiology 29 (3), 224-237, 2021
862021
An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye
D Jaishankar, AM Yakoub, T Yadavalli, A Agelidis, N Thakkar, S Hadigal, ...
Science translational medicine 10 (428), eaan5861, 2018
762018
Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery
T Yadavalli, J Ames, A Agelidis, R Suryawanshi, D Jaishankar, J Hopkins, ...
Science advances 5 (8), eaax0780, 2019
592019
Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells
JA Callahan, GE Hammer, A Agelides, BH Duong, S Oshima, J North, ...
The Journal of Immunology 191 (2), 535-539, 2013
592013
Targeting herpes simplex virus-1 gD by a DNA aptamer can be an effective new strategy to curb viral infection
T Yadavalli, A Agelidis, D Jaishankar, K Mangano, N Thakkar, ...
Molecular Therapy-Nucleic Acids 9, 365-378, 2017
492017
An intra-vaginal zinc oxide tetrapod nanoparticles (ZOTEN) and genital herpesvirus cocktail can provide a novel platform for live virus vaccine
A Agelidis, L Koujah, R Suryawanshi, T Yadavalli, YK Mishra, R Adelung, ...
Frontiers in immunology 10, 435429, 2019
482019
Heparanase, heparan sulfate and viral infection
A Agelidis, D Shukla
Heparanase: From Basic Research to Clinical Applications, 759-770, 2020
422020
Host enzymes heparanase and cathepsin L promote herpes simplex virus 2 release from cells
J Hopkins, T Yadavalli, AM Agelidis, D Shukla
Journal of Virology 92 (23), 10.1128/jvi. 01179-18, 2018
422018
Heparanase-regulated syndecan-1 shedding facilitates herpes simplex virus 1 egress
S Hadigal, R Koganti, T Yadavalli, A Agelidis, R Suryawanshi, D Shukla
Journal of Virology 94 (6), 10.1128/jvi. 01672-19, 2020
342020
OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection
J Ames, T Yadavalli, R Suryawanshi, J Hopkins, A Agelidis, C Patil, ...
Nature communications 12 (1), 5401, 2021
312021
Bacterial pigment prodigiosin demonstrates a unique antiherpesvirus activity that is mediated through inhibition of prosurvival signal transducers
RK Suryawanshi, L Koujah, CD Patil, JM Ames, A Agelidis, T Yadavalli, ...
Journal of Virology 94 (13), 10.1128/jvi. 00251-20, 2020
262020
Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival
A Agelidis, BA Turturice, RK Suryawanshi, T Yadavalli, D Jaishankar, ...
JCI insight 6 (7), 2021
152021
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing
T Yadavalli, R Suryawanshi, R Koganti, J Hopkins, J Ames, L Koujah, ...
Science Advances 6 (49), eabd9443, 2020
142020
Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells
N Thakkar, D Jaishankar, A Agelidis, T Yadavalli, K Mangano, S Patel, ...
Scientific reports 7 (1), 42559, 2017
142017
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Articles 1–20