| Engineered LINE-1 retrotransposition in nondividing human neurons A Macia, TJ Widmann, SR Heras, V Ayllon, L Sanchez, ... Genome research 27 (3), 335-348, 2017 | 161 | 2017 |
| The Microprocessor controls the activity of mammalian retrotransposons SR Heras, S Macias, M Plass, N Fernandez, D Cano, E Eyras, ... Nature structural & molecular biology 20 (10), 1173-1181, 2013 | 129 | 2013 |
| The translational landscape of the splicing factor SRSF1 and its role in mitosis MM Maslon, SR Heras, N Bellora, E Eyras, JF Cáceres Elife 3, e02028, 2014 | 128 | 2014 |
| LINE-1 evasion of epigenetic repression in humans FJ Sanchez-Luque, MJHC Kempen, P Gerdes, DB Vargas-Landin, ... Molecular cell 75 (3), 590-604. e12, 2019 | 122 | 2019 |
| Genome-wide de novo L1 retrotransposition connects endonuclease activity with replication DA Flasch, Á Macia, L Sánchez, M Ljungman, SR Heras, JL García-Pérez, ... Cell 177 (4), 837-851. e28, 2019 | 114 | 2019 |
| RNase H2, mutated in Aicardi‐Goutières syndrome, promotes LINE‐1 retrotransposition M Benitez‐Guijarro, C Lopez‐Ruiz, Ž Tarnauskaitė, O Murina, ... The EMBO Journal 37 (15), e98506, 2018 | 74 | 2018 |
| Identification of non-autonomous non-LTR retrotransposons in the genome of Trypanosoma cruzi F Bringaud, JL Garcı́a-Pérez, SR Heras, E Ghedin, NM El-Sayed, ... Molecular and biochemical parasitology 124 (1-2), 73-78, 2002 | 59 | 2002 |
| Transcriptional profiling of HERV-K (HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins J Mayer, C Harz, L Sanchez, GC Pereira, E Maldener, SR Heras, ... Molecular neurodegeneration 13, 1-25, 2018 | 57 | 2018 |
| Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor A Morales-Hernández, FJ González-Rico, AC Román, E Rico-Leo, ... Nucleic acids research 44 (10), 4665-4683, 2016 | 51 | 2016 |
| L1Tc non-LTR retrotransposons from Trypanosoma cruzi contain a functional viral-like self-cleaving 2A sequence in frame with the active proteins they encode SR Heras, MC Thomas, M Garcia-Canadas, P Felipe, JL Garcia-Perez, ... Cellular and Molecular Life Sciences CMLS 63, 1449-1460, 2006 | 49 | 2006 |
| Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis GC Pereira, L Sanchez, PM Schaughency, A Rubio-Roldán, JA Choi, ... Mobile Dna 9, 1-30, 2018 | 47 | 2018 |
| The L1Tc non-LTR retrotransposon of Trypanosoma cruzi contains an internal RNA-pol II-dependent promoter that strongly activates gene transcription and … SR Heras, MC Lopez, M Olivares, MC Thomas Nucleic acids research 35 (7), 2199-2214, 2007 | 46 | 2007 |
| The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition P Tristán-Ramos, A Rubio-Roldan, G Peris, L Sánchez, S Amador-Cubero, ... Nature Communications 11 (1), 5712, 2020 | 45 | 2020 |
| Sensing of transposable elements by the antiviral innate immune system A Gázquez-Gutiérrez, J Witteveldt, SR Heras, S Macias Rna 27 (7), 735-752, 2021 | 36 | 2021 |
| The Non-LTR (Long Terminal Repeat) Retrotransposon L1Tc fromTrypanosoma cruzi Codes for a Protein with RNase H Activity M Olivares, JL Garcı́a-Pérez, MC Thomas, SR Heras, MC López Journal of Biological Chemistry 277 (31), 28025-28030, 2002 | 34 | 2002 |
| Control of mammalian retrotransposons by cellular RNA processing activities SR Heras, S Macias, JF Cáceres, JL Garcia-Perez Mobile genetic elements 4 (2), 1173-81, 2014 | 33 | 2014 |
| Synthesis and characterization of specific reverse transcriptase inhibitors for mammalian LINE-1 retrotransposons G Banuelos-Sanchez, L Sanchez, M Benitez-Guijarro, ... Cell Chemical Biology 26 (8), 1095-1109. e14, 2019 | 28 | 2019 |
| The L1Tc C-terminal domain from Trypanosoma cruzi non-long terminal repeat retrotransposon codes for a protein that bears two C2H2 zinc finger motifs and is endowed with … SR Heras, MC López, JL García-Pérez, SL Martin, MC Thomas Molecular and cellular biology, 2005 | 26 | 2005 |
| The impact of transposable element activity on therapeutically relevant human stem cells GG Schumann, NV Fuchs, P Tristán-Ramos, A Sebe, Z Ivics, SR Heras Mobile DNA 10, 1-23, 2019 | 22 | 2019 |
| Nucleic-acid-binding properties of the C2-L1Tc nucleic acid chaperone encoded by L1Tc retrotransposon SR Heras, MC Thomas, F Macias, ME Patarroyo, C Alonso, MC López Biochemical Journal 424 (3), 479-490, 2009 | 15 | 2009 |
Javier F. CaceresMRC Human Genetics UnitVerified email at ed.ac.uk
