| SARS-CoV-2 infection of pluripotent stem cell-derived human lung alveolar type 2 cells elicits a rapid epithelial-intrinsic inflammatory response J Huang, AJ Hume, KM Abo, RB Werder, C Villacorta-Martin, ... Cell stem cell 27 (6), 962-973. e7, 2020 | 322 | 2020 |
| SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes Y Li, DM Renner, CE Comar, JN Whelan, HM Reyes, FL Cardenas-Diaz, ... Proceedings of the National Academy of Sciences 118 (16), e2022643118, 2021 | 213 | 2021 |
| Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 C Mirabelli, JW Wotring, CJ Zhang, SM McCarty, R Fursmidt, CD Pretto, ... Proceedings of the National Academy of Sciences 118 (36), e2105815118, 2021 | 193 | 2021 |
| Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells T Shiraishi, JE Verdone, J Huang, UD Kahlert, JR Hernandez, G Torga, ... Oncotarget 6 (1), 130, 2015 | 180 | 2015 |
| Reconstructed single-cell fate trajectories define lineage plasticity windows during differentiation of human PSC-derived distal lung progenitors K Hurley, J Ding, C Villacorta-Martin, MJ Herriges, A Jacob, M Vedaie, ... Cell Stem Cell 26 (4), 593-608. e8, 2020 | 118 | 2020 |
| Mechanical stress determines the configuration of TGFβ activation in articular cartilage G Zhen, Q Guo, Y Li, C Wu, S Zhu, R Wang, XE Guo, BC Kim, J Huang, ... Nature communications 12 (1), 1706, 2021 | 106 | 2021 |
| Defining an olfactory receptor function in airway smooth muscle cells WH Aisenberg, J Huang, W Zhu, P Rajkumar, R Cruz, L Santhanam, ... Scientific reports 6 (1), 38231, 2016 | 100 | 2016 |
| Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells AFM Dost, AL Moye, M Vedaie, LM Tran, E Fung, D Heinze, ... Cell Stem Cell 27 (4), 663-678. e8, 2020 | 97 | 2020 |
| Actionable cytopathogenic host responses of human alveolar type 2 cells to SARS-CoV-2 RM Hekman, AJ Hume, RK Goel, KM Abo, J Huang, BC Blum, RB Werder, ... Molecular cell 80 (6), 1104-1122. e9, 2020 | 94 | 2020 |
| An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma SS An, W Mitzner, WY Tang, K Ahn, AR Yoon, J Huang, O Kilic, HM Yong, ... Journal of Allergy and Clinical Immunology 138 (1), 294-297. e4, 2016 | 60 | 2016 |
| Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors KM Abo, L Ma, T Matte, J Huang, KD Alysandratos, RB Werder, A Mithal, ... Biorxiv, 2020 | 58 | 2020 |
| Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors KM Abo, L Ma, T Matte, J Huang, KD Alysandratos, RB Werder, A Mithal, ... Biorxiv, 2020 | 58 | 2020 |
| Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression RM Hughes, BW Simons, H Khan, R Miller, V Kugler, S Torquato, ... Cancer research 79 (14), 3636-3650, 2019 | 55 | 2019 |
| YAP and TAZ regulate cell volume NA Perez-Gonzalez, ND Rochman, K Yao, J Tao, MTT Le, S Flanary, ... Journal of Cell Biology 218 (10), 3472-3488, 2019 | 44 | 2019 |
| TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness W Zhu, BC Kim, M Wang, J Huang, A Isak, NM Bexiga, R Monticone, T Ha, ... Scientific reports 8 (1), 2668, 2018 | 37 | 2018 |
| Germline variants in asporin vary by race, modulate the tumor microenvironment, and are differentially associated with metastatic prostate cancer PJ Hurley, D Sundi, B Shinder, BW Simons, RM Hughes, RM Miller, ... Clinical cancer research 22 (2), 448-458, 2016 | 37 | 2016 |
| Reproducible uniform equibiaxial stretch of precision-cut lung slices N Davidovich, J Huang, SS Margulies Am J Physiol Lung Cell Mol Physiol 304, L210–L220, 2013 | 30 | 2013 |
| Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells KD Alysandratos, C Garcia-de-Alba, C Yao, P Pessina, J Huang, ... JCI insight 8 (1), 2023 | 27 | 2023 |
| Androgen-regulated SPARCL1 in the tumor microenvironment inhibits metastatic progression PJ Hurley, RM Hughes, BW Simons, J Huang, RM Miller, B Shinder, ... Cancer research 75 (20), 4322-4334, 2015 | 26 | 2015 |
| Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium KM Abo, JS de Aja, J Lindstrom-Vautrin, KD Alysandratos, A Richards, ... JCI insight 7 (6), 2022 | 22 | 2022 |
