| Unique CD14+ intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-γ axis N Kamada, T Hisamatsu, S Okamoto, H Chinen, T Kobayashi, T Sato, ... The Journal of clinical investigation 118 (6), 2269-2280, 2008 | 832 | 2008 |
| IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn’s disease T Kobayashi, S Okamoto, T Hisamatsu, N Kamada, H Chinen, R Saito, ... Gut 57 (12), 1682-1689, 2008 | 711 | 2008 |
| Evidence-based clinical practice guidelines for inflammatory bowel disease K Matsuoka, T Kobayashi, F Ueno, T Matsui, F Hirai, N Inoue, J Kato, ... Journal of gastroenterology 53 (3), 305-353, 2018 | 501 | 2018 |
| Evidence-based clinical practice guidelines for inflammatory bowel disease 2020 H Nakase, M Uchino, S Shinzaki, M Matsuura, K Matsuoka, T Kobayashi, ... Journal of gastroenterology 56 (6), 489-526, 2021 | 285 | 2021 |
| Th17 plasticity and its relevance to inflammatory bowel disease A Ueno, L Jeffery, T Kobayashi, T Hibi, S Ghosh, H Jijon Journal of autoimmunity 87, 38-49, 2018 | 245 | 2018 |
| Efficacy and safety of vedolizumab subcutaneous formulation in a randomized trial of patients with ulcerative colitis WJ Sandborn, F Baert, S Danese, Ž Krznarić, T Kobayashi, X Yao, J Chen, ... Gastroenterology 158 (3), 562-572. e12, 2020 | 243 | 2020 |
| Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis S Serada, M Fujimoto, F Terabe, H Iijima, S Shinzaki, S Matsuzaki, ... Inflammatory bowel diseases 18 (11), 2169-2179, 2012 | 208 | 2012 |
| Efficacy of indigo naturalis in a multicenter randomized controlled trial of patients with ulcerative colitis M Naganuma, S Sugimoto, K Mitsuyama, T Kobayashi, N Yoshimura, ... Gastroenterology 154 (4), 935-947, 2018 | 179 | 2018 |
| An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis SZ Sheikh, RA Hegazi, T Kobayashi, JC Onyiah, SM Russo, K Matsuoka, ... The Journal of Immunology 186 (9), 5506-5513, 2011 | 171 | 2011 |
| Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages A Andou, T Hisamatsu, S Okamoto, H Chinen, N Kamada, T Kobayashi, ... Gastroenterology 136 (2), 564-574. e2, 2009 | 162 | 2009 |
| Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10–producing regulatory macrophage subset Y Takada, T Hisamatsu, N Kamada, MT Kitazume, H Honda, Y Oshima, ... The Journal of Immunology 184 (5), 2671-2676, 2010 | 159 | 2010 |
| Measurement of the production cross section of prompt J/ψ mesons in association with a W ± boson in pp collisions at = 7 TeV with the ATLAS detector G Aad, T Abajyan, B Abbott, J Abdallah, S Abdel Khalek, R Aben, B Abi, ... Journal of High Energy Physics 2014 (4), 1-37, 2014 | 158 | 2014 |
| TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease N Kamada, T Hisamatsu, H Honda, T Kobayashi, H Chinen, T Takayama, ... Inflammatory bowel diseases 16 (4), 568-575, 2010 | 140 | 2010 |
| Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability N Kamada, T Hisamatsu, H Honda, T Kobayashi, H Chinen, MT Kitazume, ... The Journal of Immunology 183 (3), 1724-1731, 2009 | 128 | 2009 |
| Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance JC Onyiah, SZ Sheikh, N Maharshak, EC Steinbach, SM Russo, ... Gastroenterology 144 (4), 789-798, 2013 | 125 | 2013 |
| First trough level of infliximab at week 2 predicts future outcomes of induction therapy in ulcerative colitis—results from a multicenter prospective randomized controlled … T Kobayashi, Y Suzuki, S Motoya, F Hirai, H Ogata, H Ito, N Sato, K Ozaki, ... Journal of gastroenterology 51, 241-251, 2016 | 119 | 2016 |
| NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity T Kobayashi, K Matsuoka, SZ Sheikh, HZ Elloumi, N Kamada, ... The Journal of Immunology 186 (8), 4649-4655, 2011 | 114 | 2011 |
| NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter … Y Kakuta, Y Kawai, D Okamoto, T Takagawa, K Ikeya, H Sakuraba, ... Journal of gastroenterology 53, 1065-1078, 2018 | 111 | 2018 |
| Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells H Chinen, K Matsuoka, T Sato, N Kamada, S Okamoto, T Hisamatsu, ... Gastroenterology 133 (2), 559-573, 2007 | 110 | 2007 |
| Exclusive increase of CX3CR1+CD28−CD4+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes T Kobayashi, S Okamoto, Y Iwakami, A Nakazawa, T Hisamatsu, ... Inflammatory bowel diseases 13 (7), 837-846, 2007 | 105 | 2007 |
Shinichiro ShinzakiProfessor and Chair, Hyogo Medical University, Nishinomiya, Hyogo, Japan
