| Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease SL Bernstein, NF Dupuis, ND Lazo, T Wyttenbach, MM Condron, G Bitan, ... Nature chemistry 1 (4), 326, 2009 | 1030 | 2009 |
| Ion mobility–mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation C Bleiholder, NF Dupuis, T Wyttenbach, MT Bowers Nature chemistry 3 (2), 172, 2011 | 399 | 2011 |
| Human islet amyloid polypeptide monomers form ordered β-hairpins: a possible direct amyloidogenic precursor NF Dupuis, C Wu, JE Shea, MT Bowers Journal of the American Chemical Society 131 (51), 18283-18292, 2009 | 250 | 2009 |
| The amyloid formation mechanism in human IAPP: dimers have β-strand monomer− monomer interfaces NF Dupuis, C Wu, JE Shea, MT Bowers Journal of the American Chemical Society 133 (19), 7240-7243, 2011 | 236 | 2011 |
| A new, higher resolution, ion mobility mass spectrometer PR Kemper, NF Dupuis, MT Bowers International Journal of Mass Spectrometry 287 (1-3), 46-57, 2009 | 227 | 2009 |
| Molecular-crowding effects on single-molecule RNA folding/unfolding thermodynamics and kinetics NF Dupuis, ED Holmstrom, DJ Nesbitt Proceedings of the National Academy of Sciences 111 (23), 8464-8469, 2014 | 155 | 2014 |
| Single-molecule kinetics reveal cation-promoted DNA duplex formation through ordering of single-stranded helices NF Dupuis, ED Holmstrom, DJ Nesbitt Biophysical journal 105 (3), 756-766, 2013 | 109 | 2013 |
| Biomarkers predict enhanced clinical outcomes with afatinib versus methotrexate in patients with second-line recurrent and/or metastatic head and neck cancer EEW Cohen, LF Licitra, B Burtness, J Fayette, T Gauler, PM Clement, ... Annals of Oncology 28 (10), 2526-2532, 2017 | 85 | 2017 |
| Defining the molecular basis of amyloid inhibitors: human islet amyloid polypeptide–insulin interactions AC Susa, C Wu, SL Bernstein, NF Dupuis, H Wang, DP Raleigh, JE Shea, ... Journal of the American Chemical Society 136 (37), 12912-12919, 2014 | 81 | 2014 |
| Spermine binding to Parkinson’s protein α-synuclein and its disease-related A30P and A53T mutants M Grabenauer, SL Bernstein, JC Lee, T Wyttenbach, NF Dupuis, HB Gray, ... The journal of physical chemistry B 112 (35), 11147-11154, 2008 | 74 | 2008 |
| DNA hairpin, pseudoknot, and cruciform stability in a solvent-free environment ES Baker, NF Dupuis, MT Bowers The Journal of Physical Chemistry B 113 (6), 1722-1727, 2009 | 47 | 2009 |
| Development and clinical utility of a blood-based test service for the rapid identification of actionable mutations in non–small cell lung carcinoma H Mellert, T Foreman, L Jackson, D Maar, S Thurston, K Koch, A Weaver, ... The Journal of Molecular Diagnostics 19 (3), 404-416, 2017 | 41 | 2017 |
| Kinetic and thermodynamic origins of osmolyte-influenced nucleic acid folding ED Holmstrom, NF Dupuis, DJ Nesbitt The Journal of Physical Chemistry B 119 (9), 3687-3696, 2015 | 33 | 2015 |
| Evaluation of the VeriStrat® serum protein test in patients with advanced squamous cell carcinoma of the lung treated with second-line afatinib or erlotinib in the phase III … S Gadgeel, G Goss, JC Soria, E Felip, V Georgoulias, S Lu, M Cobo, ... Lung Cancer 109, 101-108, 2017 | 31 | 2017 |
| Probing Shapes of Bichromophoric Metal− Organic Complexes Using Ion Mobility Mass Spectrometry ES Baker, JE Bushnell, SR Wecksler, MD Lim, MJ Manard, NF Dupuis, ... Journal of the American Chemical Society 127 (51), 18222-18228, 2005 | 31 | 2005 |
| Pulsed IR heating studies of single-molecule DNA duplex dissociation kinetics and thermodynamics ED Holmstrom, NF Dupuis, DJ Nesbitt Biophysical journal 106 (1), 220-231, 2014 | 28 | 2014 |
| Laser control of product electronic state: Desorption from alkali halides KM Beck, AG Joly, NF Dupuis, P Perozzo, WP Hess, PV Sushko, ... The Journal of chemical physics 120 (5), 2456-2463, 2004 | 18 | 2004 |
| Tests of Kramers’ theory at the single-molecule level: evidence for folding of an isolated RNA tertiary interaction at the viscous speed limit NF Dupuis, ED Holmstrom, DJ Nesbitt The Journal of Physical Chemistry B 122 (38), 8796-8804, 2018 | 16 | 2018 |
| Biomarker analysis in recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) patients (pts) treated with second-line afatinib versus methotrexate (MTX … EEW Cohen, LF Licitra, J Fayette, TC Gauler, PM Clement, JJ Grau, ... Journal of Clinical Oncology 33 (15_suppl), 6023-6023, 2015 | 14 | 2015 |
| Dimerization of chirally mutated enkephalin neurotransmitters: implications for peptide and protein aggregation mechanisms C Bleiholder, NF Dupuis, MT Bowers The Journal of Physical Chemistry B 117 (6), 1770-1779, 2013 | 12 | 2013 |
