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Peter Blume-Jensen
Peter Blume-Jensen
CEO, President, Founder at Acrivon Therapeutics
Verified email at acrivon.com - Homepage
Title
Cited by
Cited by
Year
Oncogenic kinase signalling
P Blume-Jensen, T Hunter
Nature 411 (6835), 355-365, 2001
52562001
The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136
P Blume-Jensen, R Janknecht, T Hunter
Current biology 8 (13), 779-785, 1998
4781998
Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase
Z Lu, G Jiang, P Blume-Jensen, T Hunter
Molecular and cellular biology, 2001
4282001
Activation of the human c‐kit product by ligand‐induced dimerization mediates circular actin reorganization and chemotaxis.
P Blume‐Jensen, L Claesson‐Welsh, A Siegbahn, KM Zsebo, ...
The EMBO journal 10 (13), 4121-4128, 1991
3991991
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3′-kinase is essential for male fertility
P Blume-Jensen, G Jiang, R Hyman, KF Lee, S O'Gorman, T Hunter
Nature genetics 24 (2), 157-162, 2000
3662000
Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction
J Lennartsson, P Blume-Jensen, M Hermanson, E Pontén, M Carlberg, ...
Oncogene 18 (40), 5546-5553, 1999
2391999
Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors
JN Andersen, S Sathyanarayanan, A Di Bacco, A Chi, T Zhang, AH Chen, ...
Science translational medicine 2 (43), 43ra55-43ra55, 2010
2232010
Development and Clinical Validation of an In Situ Biopsy-Based Multimarker Assay for Risk Stratification in Prostate Cancer
P Blume-Jensen, DM Berman, DL Rimm, M Shipitsin, M Putzi, TP Nifong, ...
Clinical cancer research 21 (11), 2591-2600, 2015
1992015
Identification of proteomic biomarkers predicting prostate cancer aggressiveness and lethality despite biopsy-sampling error
M Shipitsin, C Small, S Choudhury, E Giladi, S Friedlander, J Nardone, ...
British journal of cancer 111 (6), 1201-1212, 2014
1642014
Fibroblast growth factor receptor-1 regulation of Src family kinases.
E Landgren, P Blume-Jensen, SA Courtneidge, L Claesson-Welsh
Oncogene 10 (10), 2027-2035, 1995
1321995
Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C.
P Blume‐Jensen, A Siegbahn, S Stabel, CH Heldin, L Rönnstrand
The EMBO journal 12 (11), 4199-4209, 1993
1301993
Modulation of Kit/stem cell factor receptor-induced signaling by protein kinase C.
P Blume-Jensen, L Rönnstrand, I Gout, MD Waterfield, CH Heldin
Journal of Biological Chemistry 269 (34), 21793-21802, 1994
1271994
Identification of the Major Phosphorylation Sites for Protein Kinase C in Kit/Stem Cell Factor Receptor in Vitro and in Intact Cells∗
P Blume-Jensen, C Wernstedt, CH Heldin, L Rönnstrand
Journal of Biological Chemistry 270 (23), 14192-14200, 1995
1211995
Genetic and pharmacological inhibition of PDK1 in cancer cells: characterization of a selective allosteric kinase inhibitor
K Nagashima, SD Shumway, S Sathyanarayanan, AH Chen, B Dolinski, ...
Journal of biological chemistry 286 (8), 6433-6448, 2011
772011
Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate …
M Shipitsin, C Small, E Giladi, S Siddiqui, S Choudhury, S Hussain, ...
Proteome Science 12, 1-13, 2014
682014
Discovery of PDK1 kinase inhibitors with a novel mechanism of action by ultrahigh throughput screening
EV Bobkova, MJ Weber, Z Xu, YL Zhang, J Jung, P Blume-Jensen, ...
Journal of biological chemistry 285 (24), 18838-18846, 2010
582010
Involvement of phosphatidylinositol 3′‐kinase in stem‐cell‐factor‐induced phospholipase D activation and arachidonic acid release
O Kozawa, P Blume‐Jensen, CH Heldin, L Rönnstrand
European journal of biochemistry 248 (1), 149-155, 1997
531997
PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models
K Ellwood-Yen, H Keilhack, K Kunii, B Dolinski, Y Connor, K Hu, ...
Cancer research 71 (8), 3052-3065, 2011
352011
The platelet-derived growth factor beta-receptor kinase insert confers specific signaling properties to a chimeric fibroblast growth factor receptor.
S Wennström, E Landgren, P Blume-Jensen, L Claesson-Welsh
Journal of Biological Chemistry 267 (19), 13749-13756, 1992
321992
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs
MR Golder, J Liu, JN Andersen, MV Shipitsin, F Vohidov, HVT Nguyen, ...
Nature biomedical engineering 2 (11), 822-830, 2018
292018
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