| Serotonin 5-HT7 receptor agents: structure-activity relationships and potential therapeutic applications in central nervous system disorders M Leopoldo, E Lacivita, F Berardi, R Perrone, PB Hedlund Pharmacology & therapeutics 129 (2), 120-148, 2011 | 220 | 2011 |
| International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function NM Barnes, GP Ahern, C Becamel, J Bockaert, M Camilleri, ... Pharmacological reviews 73 (1), 310-520, 2021 | 157 | 2021 |
| Interplay between Serotonin 5‐HT1A and 5‐HT7 Receptors in Depressive Disorders VS Naumenko, NK Popova, E Lacivita, M Leopoldo, EG Ponimaskin CNS neuroscience & therapeutics 20 (7), 582-590, 2014 | 148 | 2014 |
| Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome L Costa, M Spatuzza, S D'Antoni, CM Bonaccorso, C Trovato, ... Biological psychiatry 72 (11), 924-933, 2012 | 135 | 2012 |
| Developments in fluorescent probes for receptor research M Leopoldo, E Lacivita, F Berardi, R Perrone Drug discovery today 14 (13-14), 706-712, 2009 | 105 | 2009 |
| Structure−Affinity Relationship Study on N-[4-(4-Arylpiperazin-1-yl)butyl]arylcarboxamides as Potent and Selective Dopamine D3 Receptor Ligands M Leopoldo, F Berardi, NA Colabufo, P De Giorgio, E Lacivita, R Perrone, ... Journal of medicinal chemistry 45 (26), 5727-5735, 2002 | 104 | 2002 |
| 5-HT1A receptor, an old target for new therapeutic agents E Lacivita, M Leopoldo, F Berardi, R Perrone Current Topics in Medicinal Chemistry 8 (12), 1024-1034, 2008 | 99 | 2008 |
| Structural Modifications of N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-piperazinehexanamides: Influence on Lipophilicity and 5-HT7 Receptor Activity. Part III M Leopoldo, E Lacivita, P De Giorgio, C Fracasso, S Guzzetti, S Caccia, ... Journal of medicinal chemistry 51 (18), 5813-5822, 2008 | 90 | 2008 |
| LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor PB Hedlund, M Leopoldo, S Caccia, G Sarkisyan, C Fracasso, G Martelli, ... Neuroscience letters 481 (1), 12-16, 2010 | 87 | 2010 |
| Serotonin 5‐HT 7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons L Speranza, J Labus, F Volpicelli, D Guseva, E Lacivita, M Leopoldo, ... Journal of Neurochemistry 141 (5), 647-661, 2017 | 83 | 2017 |
| Structure−Affinity Relationship Study on N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-Piperazinealkylamides, a New Class of 5-Hydroxytryptamine7 Receptor … M Leopoldo, F Berardi, NA Colabufo, M Contino, E Lacivita, M Niso, ... Journal of medicinal chemistry 47 (26), 6616-6624, 2004 | 83 | 2004 |
| Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome B De Filippis, P Nativio, A Fabbri, L Ricceri, W Adriani, E Lacivita, ... Neuropsychopharmacology 39 (11), 2506-2518, 2014 | 80 | 2014 |
| Structure−Activity Relationship Study on N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a Class of 5-HT7 Receptor Agents. 2 M Leopoldo, E Lacivita, M Contino, NA Colabufo, F Berardi, R Perrone Journal of medicinal chemistry 50 (17), 4214-4221, 2007 | 77 | 2007 |
| Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice W Adriani, D Travaglini, E Lacivita, L Saso, M Leopoldo, G Laviola Neuropharmacology 62 (2), 833-842, 2012 | 72 | 2012 |
| Synthesis and Structure−Affinity Relationships of 1-[ω-(4-Aryl-1-piperazinyl)alkyl]-1-aryl Ketones as 5-HT7 Receptor Ligands R Perrone, F Berardi, NA Colabufo, E Lacivita, M Leopoldo, V Tortorella Journal of medicinal chemistry 46 (4), 646-649, 2003 | 72 | 2003 |
| Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 … L Costa, LM Sardone, E Lacivita, M Leopoldo, L Ciranna Frontiers in behavioral neuroscience 9, 65, 2015 | 64 | 2015 |
| Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview P Di Pilato, M Niso, W Adriani, E Romano, D Travaglini, F Berardi, ... Reviews in the Neurosciences 25 (3), 401-415, 2014 | 64 | 2014 |
| 4-[ω-[4-Arylpiperazin-1-yl] alkoxy] phenyl) imidazo [1, 2-a] pyridine derivatives: fluorescent high-affinity dopamine D3 receptor ligands as potential probes for receptor … M Leopoldo, E Lacivita, E Passafiume, M Contino, NA Colabufo, F Berardi, ... Journal of medicinal chemistry 50 (20), 5043-5047, 2007 | 62 | 2007 |
| Targets for drug therapy for autism spectrum disorder: challenges and future directions E Lacivita, R Perrone, L Margari, M Leopoldo Journal of medicinal chemistry 60 (22), 9114-9141, 2017 | 61 | 2017 |
| Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome B De Filippis, V Chiodi, W Adriani, E Lacivita, C Mallozzi, M Leopoldo, ... Frontiers in Behavioral Neuroscience 9, 86, 2015 | 57 | 2015 |
