| Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1 JF Reichard, GT Motz, A Puga Nucleic acids research 35 (21), 7074-7086, 2007 | 420 | 2007 |
| The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 391 | 2018 |
| Effects of arsenic exposure on DNA methylation and epigenetic gene regulation JF Reichard, A Puga Epigenomics 2 (1), 87-104, 2010 | 356 | 2010 |
| Long term low-dose arsenic exposure induces loss of DNA methylation JF Reichard, M Schnekenburger, A Puga Biochemical and biophysical research communications 352 (1), 188-192, 2007 | 350 | 2007 |
| Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data A Koleti, R Terryn, V Stathias, C Chung, DJ Cooper, JP Turner, D Vidović, ... Nucleic acids research 46 (D1), D558-D566, 2018 | 168 | 2018 |
| 4-Hydroxynonenal and malondialdehyde hepatic protein adducts in rats treated with carbon tetrachloride: immunochemical detection and lobular localization DP Hartley, KL Kolaja, J Reichard, DR Petersen Toxicology and applied pharmacology 161 (1), 23-33, 1999 | 147 | 1999 |
| Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs MA Sartor, M Schnekenburger, JL Marlowe, JF Reichard, Y Wang, Y Fan, ... Environmental Health Perspectives 117 (7), 1139-1146, 2009 | 114 | 2009 |
| Arsenic toxicology: translating between experimental models and human pathology JC States, A Barchowsky, IL Cartwright, JF Reichard, BW Futscher, ... Environmental health perspectives 119 (10), 1356-1363, 2011 | 94 | 2011 |
| BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite JF Reichard, MA Sartor, A Puga Journal of biological chemistry 283 (33), 22363-22370, 2008 | 85 | 2008 |
| Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study RA Budinsky, D Schrenk, T Simon, M Van den Berg, JF Reichard, ... Critical reviews in toxicology 44 (1), 83-119, 2014 | 84 | 2014 |
| Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes S Kann, M Huang, C Estes, JF Reichard, MA Sartor, Y Xia, A Puga Molecular pharmacology 68 (2), 336-346, 2005 | 80 | 2005 |
| Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor JF Reichard, TP Dalton, HG Shertzer, A Puga Dose-Response 3 (3), dose-response. 003.03. 003, 2005 | 80 | 2005 |
| Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status S Kann, C Estes, JF Reichard, M Huang, MA Sartor, S Schwemberger, ... Toxicological sciences 87 (2), 365-384, 2005 | 67 | 2005 |
| Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver JF Reichard, V Vasiliou, DR Petersen Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000 | 54 | 2000 |
| Toxicokinetic and toxicodynamic considerations when deriving health-based exposure limits for pharmaceuticals JF Reichard, MA Maier, BD Naumann, AM Pecquet, T Pfister, R Sandhu, ... Regulatory Toxicology and Pharmacology 79, S67-S78, 2016 | 45 | 2016 |
| Connecting omics signatures of diseases, drugs, and mechanisms of actions with iLINCS M Pilarczyk, M Kouril, B Shamsaei, J Vasiliauskas, W Niu, N Mahi, ... BioRxiv, 826271, 2019 | 41 | 2019 |
| Connecting omics signatures and revealing biological mechanisms with iLINCS M Pilarczyk, M Fazel-Najafabadi, M Kouril, B Shamsaei, J Vasiliauskas, ... Nature communications 13 (1), 4678, 2022 | 35 | 2022 |
| Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules J Chen, Z Hu, M Phatak, J Reichard, JM Freudenberg, S Sivaganesan, ... PLoS computational biology 9 (9), e1003198, 2013 | 32 | 2013 |
| Characterization of multidrug resistance-associated protein 2 in the hepatocellular disposition of 4-hydroxynonenal JF Reichard, JA Doorn, F Simon, MS Taylor, DR Petersen Archives of biochemistry and biophysics 411 (2), 243-250, 2003 | 32 | 2003 |
| Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1, 4-dioxane ML Dourson, J Higginbotham, J Crum, H Burleigh-Flayer, P Nance, ... Regulatory Toxicology and Pharmacology 88, 45-55, 2017 | 31 | 2017 |
