| The support of human genetic evidence for approved drug indications MR Nelson, H Tipney, JL Painter, J Shen, P Nicoletti, Y Shen, A Floratos, ... Nature genetics 47 (8), 856-860, 2015 | 1301 | 2015 |
| An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people MR Nelson, D Wegmann, MG Ehm, D Kessner, P St. Jean, C Verzilli, ... Science 337 (6090), 100-104, 2012 | 799 | 2012 |
| HIBAG—HLA genotype imputation with attribute bagging X Zheng, J Shen, C Cox, JC Wakefield, MG Ehm, MR Nelson, BS Weir The pharmacogenomics journal 14 (2), 192-200, 2014 | 418 | 2014 |
| Multi-population classical HLA type imputation A Dilthey, S Leslie, L Moutsianas, J Shen, C Cox, MR Nelson, G McVean PLoS computational biology 9 (2), e1002877, 2013 | 198 | 2013 |
| Determination of cluster number in clustering microarray data J Shen, SI Chang, ES Lee, Y Deng, SJ Brown Applied Mathematics and Computation 169 (2), 1172-1185, 2005 | 117 | 2005 |
| Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1* 07: 01 LR Parham, LP Briley, L Li, J Shen, PJ Newcombe, KS King, AJ Slater, ... The pharmacogenomics journal 16 (2), 180-185, 2016 | 63 | 2016 |
| Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation LL Warren, L Li, MR Nelson, MG Ehm, J Shen, DJ Fraser, JL Aponte, ... Diabetes 61 (5), 1297-1301, 2012 | 49 | 2012 |
| Multi-trait analysis of rare-variant association summary statistics using MTAR L Luo, J Shen, H Zhang, A Chhibber, DV Mehrotra, ZZ Tang Nature Communications 11 (1), 2850, 2020 | 47 | 2020 |
| No evidence of large genetic effects on steroid response in asthma patients M Mosteller, L Hosking, K Murphy, J Shen, K Song, M Nelson, S Ghosh Journal of Allergy and Clinical Immunology 139 (3), 797-803. e7, 2017 | 44 | 2017 |
| Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe JP Rubio, S Topp, L Warren, PL St. Jean, D Wegmann, D Kessner, ... Human mutation 33 (7), 1087-1098, 2012 | 36 | 2012 |
| STOPGAP: a database for systematic target opportunity assessment by genetic association predictions J Shen, K Song, AJ Slater, E Ferrero, MR Nelson Bioinformatics 33 (17), 2784-2786, 2017 | 29 | 2017 |
| Effect of Endogenous Clostridioides difficile Toxin Antibodies on Recurrence of C. difficile Infection CP Kelly, IR Poxton, J Shen, MH Wilcox, DN Gerding, X Zhao, OF Laterza, ... Clinical infectious diseases 71 (1), 81-86, 2020 | 25 | 2020 |
| Pharmacogenomics polygenic risk score for drug response prediction using PRS-PGx methods S Zhai, H Zhang, DV Mehrotra, J Shen Nature Communications 13 (1), 5278, 2022 | 23 | 2022 |
| Germline HLA landscape does not predict efficacy of pembrolizumab monotherapy across solid tumor types A Chhibber, L Huang, H Zhang, J Xu, R Cristescu, X Liu, DV Mehrotra, ... Immunity 55 (1), 56-64. e4, 2022 | 22 | 2022 |
| Global Landscape of Clostridioides Difficile Phylogeography, Antibiotic Susceptibility, and Toxin Polymorphisms by Post-Hoc Whole-Genome Sequencing from the … H Zhao, DC Nickle, Z Zeng, PYT Law, MH Wilcox, L Chen, Y Peng, ... Infectious Diseases and Therapy 10, 853-870, 2021 | 21 | 2021 |
| Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT) E Urrutia, S Lee, A Maity, N Zhao, J Shen, Y Li, MC Wu Statistics and its interface 8 (4), 495, 2015 | 16 | 2015 |
| Support vector fuzzy adaptive network in regression analysis J Shen, YR Syau, ES Lee Computers & Mathematics with Applications 54 (11-12), 1353-1366, 2007 | 16 | 2007 |
| Genetic Association Reveals Protection against Recurrence of Clostridium difficile Infection with Bezlotoxumab Treatment J Shen, DV Mehrotra, MB Dorr, Z Zeng, J Li, X Xu, D Nickle, ER Holzinger, ... MSphere 5 (3), 10.1128/msphere. 00232-20, 2020 | 15 | 2020 |
| GWAS of longitudinal trajectories at biobank scale S Ko, CA German, A Jensen, J Shen, A Wang, DV Mehrotra, YV Sun, ... The American Journal of Human Genetics 109 (3), 433-445, 2022 | 13 | 2022 |
| Modelling and analysis of waviness reduction in soft-pad grinding of wire-sawn silicon wafers by support vector regression J Shen, ZJ Pei, GR Fisher, ES Lee International journal of production research 44 (13), 2605-2623, 2006 | 13 | 2006 |
